Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CNTRL (centriolin)

Identity

Alias_namesCEP1
CEP110
centrosomal protein 1
centrosomal protein 110kDa
Other aliasFAN
bA165P4.1
HGNC (Hugo) CNTRL
LocusID (NCBI) 11064
Atlas_Id 232
Location 9q33.2  [Link to chromosome band 9q33]
Location_base_pair Starts at 121088296 and ends at 121177608 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CNTRL (9q33.2) / CNTRL (9q33.2)CNTRL (9q33.2) / FGFR1 (8p11.23)CNTRL (9q33.2) / KIT (4q12)
CNTRL (9q33.2) / MALAT1 (11q13.1)FGFR1 (8p11.23) / CNTRL (9q33.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 4 ]
  8p11 myeloproliferative syndrome (FGFR1)
t(8;9)(p12;q33) CNTRL/FGFR1
t(4;9)(q12;q33) CNTRL/KIT
t(8;9)(p11;q33) CNTRL/FGFR1

External links

Nomenclature
HGNC (Hugo)CNTRL   1858
Cards
Entrez_Gene (NCBI)CNTRL  11064  centriolin
AliasesCEP1; CEP110; FAN; bA165P4.1
GeneCards (Weizmann)CNTRL
Ensembl hg19 (Hinxton)ENSG00000119397 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119397 [Gene_View]  ENSG00000119397 [Sequence]  chr9:121088296-121177608 [Contig_View]  CNTRL [Vega]
ICGC DataPortalENSG00000119397
TCGA cBioPortalCNTRL
AceView (NCBI)CNTRL
Genatlas (Paris)CNTRL
WikiGenes11064
SOURCE (Princeton)CNTRL
Genetics Home Reference (NIH)CNTRL
Genomic and cartography
GoldenPath hg38 (UCSC)CNTRL  -     chr9:121088296-121177608 +  9q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNTRL  -     9q33.2   [Description]    (hg19-Feb_2009)
CNTRL - 9q33.2 [CytoView hg19]  CNTRL - 9q33.2 [CytoView hg38]
Mapping of homologs : NCBICNTRL [Mapview hg19]  CNTRL [Mapview hg38]
OMIM605496   
Gene and transcription
Genbank (Entrez)AA287401 AA398748 AF083322 AF513978 AK074079
RefSeq transcript (Entrez)NM_001330762 NM_007018
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CNTRL
Cluster EST : UnigeneHs.653263 [ NCBI ]
CGAP (NCI)Hs.653263
Alternative Splicing GalleryENSG00000119397
Gene ExpressionCNTRL [ NCBI-GEO ]   CNTRL [ EBI - ARRAY_EXPRESS ]   CNTRL [ SEEK ]   CNTRL [ MEM ]
Gene Expression Viewer (FireBrowse)CNTRL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11064
GTEX Portal (Tissue expression)CNTRL
Human Protein AtlasENSG00000119397-CNTRL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7A1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7A1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7A1
Splice isoforms : SwissVarQ7Z7A1
PhosPhoSitePlusQ7Z7A1
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)CEP110    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)CNTRL
DMDM Disease mutations11064
Blocks (Seattle)CNTRL
SuperfamilyQ7Z7A1
Human Protein Atlas [tissue]ENSG00000119397-CNTRL [tissue]
Peptide AtlasQ7Z7A1
HPRD05691
IPIIPI00657962   IPI00376383   IPI00887632   IPI00888387   IPI00646366   IPI00645181   IPI00643703   IPI00644195   IPI00646879   IPI00953121   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7A1
IntAct (EBI)Q7Z7A1
FunCoupENSG00000119397
BioGRIDCNTRL
STRING (EMBL)CNTRL
ZODIACCNTRL
Ontologies - Pathways
QuickGOQ7Z7A1
Ontology : AmiGOG2/M transition of mitotic cell cycle  protein tyrosine kinase activity  protein binding  centrosome  microtubule organizing center  cytosol  cytosol  cytoskeletal protein binding  regulation of G2/M transition of mitotic cell cycle  membrane  peptidyl-tyrosine phosphorylation  cell division  regulation of cytoskeleton organization  Flemming body  ciliary basal body-plasma membrane docking  centriolar subdistal appendage  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  protein tyrosine kinase activity  protein binding  centrosome  microtubule organizing center  cytosol  cytosol  cytoskeletal protein binding  regulation of G2/M transition of mitotic cell cycle  membrane  peptidyl-tyrosine phosphorylation  cell division  regulation of cytoskeleton organization  Flemming body  ciliary basal body-plasma membrane docking  centriolar subdistal appendage  
NDEx NetworkCNTRL
Atlas of Cancer Signalling NetworkCNTRL
Wikipedia pathwaysCNTRL
Orthology - Evolution
OrthoDB11064
GeneTree (enSembl)ENSG00000119397
Phylogenetic Trees/Animal Genes : TreeFamCNTRL
HOGENOMQ7Z7A1
Homologs : HomoloGeneCNTRL
Homology/Alignments : Family Browser (UCSC)CNTRL
Gene fusions - Rearrangements
Fusion : MitelmanCNTRL/FGFR1 [9q33.2/8p11.23]  
Fusion : MitelmanCNTRL/KIT [9q33.2/4q12]  [t(4;9)(q12;q33)]  
Fusion : QuiverCNTRL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNTRL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNTRL
dbVarCNTRL
ClinVarCNTRL
1000_GenomesCNTRL 
Exome Variant ServerCNTRL
ExAC (Exome Aggregation Consortium)ENSG00000119397
GNOMAD BrowserENSG00000119397
Varsome BrowserCNTRL
Genetic variants : HAPMAP11064
Genomic Variants (DGV)CNTRL [DGVbeta]
DECIPHERCNTRL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNTRL 
Mutations
ICGC Data PortalCNTRL 
TCGA Data PortalCNTRL 
Broad Tumor PortalCNTRL
OASIS PortalCNTRL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNTRL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNTRL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNTRL
DgiDB (Drug Gene Interaction Database)CNTRL
DoCM (Curated mutations)CNTRL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNTRL (select a term)
intoGenCNTRL
Cancer3DCNTRL(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605496   
Orphanet
DisGeNETCNTRL
MedgenCNTRL
Genetic Testing Registry CNTRL
NextProtQ7Z7A1 [Medical]
TSGene11064
GENETestsCNTRL
Target ValidationCNTRL
Huge Navigator CNTRL [HugePedia]
snp3D : Map Gene to Disease11064
BioCentury BCIQCNTRL
ClinGenCNTRL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11064
Chemical/Pharm GKB GenePA26414
Clinical trialCNTRL
Miscellaneous
canSAR (ICR)CNTRL (select the gene name)
DataMed IndexCNTRL
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNTRL
EVEXCNTRL
GoPubMedCNTRL
iHOPCNTRL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu May 2 12:44:26 CEST 2019
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