Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COASY (Coenzyme A synthase)

Identity

Alias_namesCoA synthase
Alias_symbol (synonym)DPCK
NBP
CoASY
PPAT
Other aliasNBIA6
UKR1
pOV-2
HGNC (Hugo) COASY
LocusID (NCBI) 80347
Atlas_Id 61974
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 42562074 and ends at 42566281 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COASY (17q21.2) / COASY (17q21.2)COASY (17q21.2) / DTD1 (20p11.23)COASY (17q21.2) / LOC100507412 (-)
COASY (17q21.2) / PPAN (19p13.2)TAF1D (11q21) / COASY (17q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COASY   29932
Cards
Entrez_Gene (NCBI)COASY  80347  Coenzyme A synthase
AliasesDPCK; NBIA6; NBP; PPAT; 
UKR1; pOV-2
GeneCards (Weizmann)COASY
Ensembl hg19 (Hinxton)ENSG00000068120 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000068120 [Gene_View]  chr17:42562074-42566281 [Contig_View]  COASY [Vega]
ICGC DataPortalENSG00000068120
TCGA cBioPortalCOASY
AceView (NCBI)COASY
Genatlas (Paris)COASY
WikiGenes80347
SOURCE (Princeton)COASY
Genetics Home Reference (NIH)COASY
Genomic and cartography
GoldenPath hg38 (UCSC)COASY  -     chr17:42562074-42566281 +  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COASY  -     17q21.2   [Description]    (hg19-Feb_2009)
EnsemblCOASY - 17q21.2 [CytoView hg19]  COASY - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBICOASY [Mapview hg19]  COASY [Mapview hg38]
OMIM609855   615643   
Gene and transcription
Genbank (Entrez)AF208536 AF453478 AK075415 AK092498 AK225485
RefSeq transcript (Entrez)NM_001042529 NM_001042530 NM_001042531 NM_001042532 NM_025233
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COASY
Cluster EST : UnigeneHs.742262 [ NCBI ]
CGAP (NCI)Hs.742262
Alternative Splicing GalleryENSG00000068120
Gene ExpressionCOASY [ NCBI-GEO ]   COASY [ EBI - ARRAY_EXPRESS ]   COASY [ SEEK ]   COASY [ MEM ]
Gene Expression Viewer (FireBrowse)COASY [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80347
GTEX Portal (Tissue expression)COASY
Human Protein AtlasENSG00000068120-COASY [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13057   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13057  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13057
Splice isoforms : SwissVarQ13057
Catalytic activity : Enzyme2.7.7.3 [ Enzyme-Expasy ]   2.7.7.32.7.7.3 [ IntEnz-EBI ]   2.7.7.3 [ BRENDA ]   2.7.7.3 [ KEGG ]   
PhosPhoSitePlusQ13057
Domaine pattern : Prosite (Expaxy)DPCK (PS51219)   
Domains : Interpro (EBI)Cyt_trans-like    Depp_CoAkinase    P-loop_NTPase    Rossmann-like_a/b/a_fold   
Domain families : Pfam (Sanger)CoaE (PF01121)    CTP_transf_like (PF01467)   
Domain families : Pfam (NCBI)pfam01121    pfam01467   
Conserved Domain (NCBI)COASY
DMDM Disease mutations80347
Blocks (Seattle)COASY
SuperfamilyQ13057
Human Protein Atlas [tissue]ENSG00000068120-COASY [tissue]
Peptide AtlasQ13057
HPRD13080
IPIIPI00184821   IPI00909064   IPI00909062   IPI00783178   
Protein Interaction databases
DIP (DOE-UCLA)Q13057
IntAct (EBI)Q13057
FunCoupENSG00000068120
BioGRIDCOASY
STRING (EMBL)COASY
ZODIACCOASY
Ontologies - Pathways
QuickGOQ13057
Ontology : AmiGOdephospho-CoA kinase activity  dephospho-CoA kinase activity  pantetheine-phosphate adenylyltransferase activity  pantetheine-phosphate adenylyltransferase activity  protein binding  ATP binding  mitochondrial outer membrane  mitochondrial matrix  coenzyme biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  phosphorylation  extracellular exosome  
Ontology : EGO-EBIdephospho-CoA kinase activity  dephospho-CoA kinase activity  pantetheine-phosphate adenylyltransferase activity  pantetheine-phosphate adenylyltransferase activity  protein binding  ATP binding  mitochondrial outer membrane  mitochondrial matrix  coenzyme biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  phosphorylation  extracellular exosome  
Pathways : KEGGPantothenate and CoA biosynthesis   
NDEx NetworkCOASY
Atlas of Cancer Signalling NetworkCOASY
Wikipedia pathwaysCOASY
Orthology - Evolution
OrthoDB80347
GeneTree (enSembl)ENSG00000068120
Phylogenetic Trees/Animal Genes : TreeFamCOASY
HOVERGENQ13057
HOGENOMQ13057
Homologs : HomoloGeneCOASY
Homology/Alignments : Family Browser (UCSC)COASY
Gene fusions - Rearrangements
Fusion: Tumor Portal COASY
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOASY [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COASY
dbVarCOASY
ClinVarCOASY
1000_GenomesCOASY 
Exome Variant ServerCOASY
ExAC (Exome Aggregation Consortium)ENSG00000068120
GNOMAD BrowserENSG00000068120
Genetic variants : HAPMAP80347
Genomic Variants (DGV)COASY [DGVbeta]
DECIPHERCOASY [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOASY 
Mutations
ICGC Data PortalCOASY 
TCGA Data PortalCOASY 
Broad Tumor PortalCOASY
OASIS PortalCOASY [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOASY  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOASY
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch COASY
DgiDB (Drug Gene Interaction Database)COASY
DoCM (Curated mutations)COASY (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COASY (select a term)
intoGenCOASY
Cancer3DCOASY(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609855    615643   
Orphanet22696   
MedgenCOASY
Genetic Testing Registry COASY
NextProtQ13057 [Medical]
TSGene80347
GENETestsCOASY
Target ValidationCOASY
Huge Navigator COASY [HugePedia]
snp3D : Map Gene to Disease80347
BioCentury BCIQCOASY
ClinGenCOASY
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80347
Chemical/Pharm GKB GenePA134867942
Clinical trialCOASY
Miscellaneous
canSAR (ICR)COASY (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOASY
EVEXCOASY
GoPubMedCOASY
iHOPCOASY
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:43:02 CET 2017

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