COBLL1 (cordon-bleu WH2 repeat protein like 1)

2011-10-01  

Identity

HGNC
COBLL1
LOCATION
2q24.3
LOCUSID
22837
ALIAS
COBLR1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22837
MIM: 610318
HGNC: 23571
Ensembl: ENSG00000082438

Variants:

dbSNP: 22837
ClinVar: 22837
TCGA: ENSG00000082438
COSMIC: COBLL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000082438ENST00000342193Q53SF7
ENSG00000082438ENST00000375458Q53SF7
ENSG00000082438ENST00000392717A0A590PXD8
ENSG00000082438ENST00000409184A0A0X1KG75
ENSG00000082438ENST00000414843C9JWZ0
ENSG00000082438ENST00000439313C9J5Y6
ENSG00000082438ENST00000444537C9JK90
ENSG00000082438ENST00000445474F8WEK0
ENSG00000082438ENST00000448708C9JAU3
ENSG00000082438ENST00000452626H7C1G2
ENSG00000082438ENST00000456171A0A0B4J1Z0
ENSG00000082438ENST00000456693C9J8C4
ENSG00000082438ENST00000629362A0A0D9SG04
ENSG00000082438ENST00000652658Q53SF7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
194015442009Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.25
204680712010Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.17
215695262011Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro.7
282327432017Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia.7
234634962013The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children.6
271853772017COBLL1, LPL and ZAP70 expression defines prognostic subgroups of chronic lymphocytic leukemia patients with high accuracy and correlates with IGHV mutational status.3
296861052018COBLL1 modulates cell morphology and facilitates androgen receptor genomic binding in advanced prostate cancer.3
267579822016Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project.1
282580262017Replication of newly identified type 2 diabetes susceptible loci in Northwest Indian population.1

Citation

Dessen P

COBLL1 (cordon-bleu WH2 repeat protein like 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52445/cobll1