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COMTD1 (catechol-O-methyltransferase domain containing 1)

Identity

Alias_symbol (synonym)FLJ23841
Other alias-
HGNC (Hugo) COMTD1
LocusID (NCBI) 118881
Atlas_Id 62019
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 75233971 and ends at 75236012 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPATCH8 (17q21.31) / COMTD1 (10q22.2)TCAP (17q12) / COMTD1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COMTD1   26309
Cards
Entrez_Gene (NCBI)COMTD1  118881  catechol-O-methyltransferase domain containing 1
Aliases
GeneCards (Weizmann)COMTD1
Ensembl hg19 (Hinxton)ENSG00000165644 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165644 [Gene_View]  chr10:75233971-75236012 [Contig_View]  COMTD1 [Vega]
ICGC DataPortalENSG00000165644
TCGA cBioPortalCOMTD1
AceView (NCBI)COMTD1
Genatlas (Paris)COMTD1
WikiGenes118881
SOURCE (Princeton)COMTD1
Genetics Home Reference (NIH)COMTD1
Genomic and cartography
GoldenPath hg38 (UCSC)COMTD1  -     chr10:75233971-75236012 -  10q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COMTD1  -     10q22.2   [Description]    (hg19-Feb_2009)
EnsemblCOMTD1 - 10q22.2 [CytoView hg19]  COMTD1 - 10q22.2 [CytoView hg38]
Mapping of homologs : NCBICOMTD1 [Mapview hg19]  COMTD1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK074421 AK290452 AK302283 AY358476 BC023663
RefSeq transcript (Entrez)NM_144589
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COMTD1
Cluster EST : UnigeneHs.355333 [ NCBI ]
CGAP (NCI)Hs.355333
Alternative Splicing GalleryENSG00000165644
Gene ExpressionCOMTD1 [ NCBI-GEO ]   COMTD1 [ EBI - ARRAY_EXPRESS ]   COMTD1 [ SEEK ]   COMTD1 [ MEM ]
Gene Expression Viewer (FireBrowse)COMTD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118881
GTEX Portal (Tissue expression)COMTD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VU5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VU5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VU5
Splice isoforms : SwissVarQ86VU5
PhosPhoSitePlusQ86VU5
Domaine pattern : Prosite (Expaxy)SAM_OMT_I (PS51682)   
Domains : Interpro (EBI)O-MeTrfase_3    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_3 (PF01596)   
Domain families : Pfam (NCBI)pfam01596   
Conserved Domain (NCBI)COMTD1
DMDM Disease mutations118881
Blocks (Seattle)COMTD1
PDB (SRS)2AVD   
PDB (PDBSum)2AVD   
PDB (IMB)2AVD   
PDB (RSDB)2AVD   
Structural Biology KnowledgeBase2AVD   
SCOP (Structural Classification of Proteins)2AVD   
CATH (Classification of proteins structures)2AVD   
SuperfamilyQ86VU5
Human Protein AtlasENSG00000165644
Peptide AtlasQ86VU5
HPRD08678
IPIIPI00642041   IPI00910238   
Protein Interaction databases
DIP (DOE-UCLA)Q86VU5
IntAct (EBI)Q86VU5
FunCoupENSG00000165644
BioGRIDCOMTD1
STRING (EMBL)COMTD1
ZODIACCOMTD1
Ontologies - Pathways
QuickGOQ86VU5
Ontology : AmiGOprotein binding  mitochondrion  O-methyltransferase activity  integral component of membrane  methylation  
Ontology : EGO-EBIprotein binding  mitochondrion  O-methyltransferase activity  integral component of membrane  methylation  
NDEx NetworkCOMTD1
Atlas of Cancer Signalling NetworkCOMTD1
Wikipedia pathwaysCOMTD1
Orthology - Evolution
OrthoDB118881
GeneTree (enSembl)ENSG00000165644
Phylogenetic Trees/Animal Genes : TreeFamCOMTD1
HOVERGENQ86VU5
HOGENOMQ86VU5
Homologs : HomoloGeneCOMTD1
Homology/Alignments : Family Browser (UCSC)COMTD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOMTD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COMTD1
dbVarCOMTD1
ClinVarCOMTD1
1000_GenomesCOMTD1 
Exome Variant ServerCOMTD1
ExAC (Exome Aggregation Consortium)COMTD1 (select the gene name)
Genetic variants : HAPMAP118881
Genomic Variants (DGV)COMTD1 [DGVbeta]
DECIPHERCOMTD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOMTD1 
Mutations
ICGC Data PortalCOMTD1 
TCGA Data PortalCOMTD1 
Broad Tumor PortalCOMTD1
OASIS PortalCOMTD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOMTD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOMTD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COMTD1
DgiDB (Drug Gene Interaction Database)COMTD1
DoCM (Curated mutations)COMTD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COMTD1 (select a term)
intoGenCOMTD1
Cancer3DCOMTD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCOMTD1
Genetic Testing Registry COMTD1
NextProtQ86VU5 [Medical]
TSGene118881
GENETestsCOMTD1
Huge Navigator COMTD1 [HugePedia]
snp3D : Map Gene to Disease118881
BioCentury BCIQCOMTD1
ClinGenCOMTD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD118881
Chemical/Pharm GKB GenePA134961676
Clinical trialCOMTD1
Miscellaneous
canSAR (ICR)COMTD1 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOMTD1
EVEXCOMTD1
GoPubMedCOMTD1
iHOPCOMTD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:06:39 CEST 2017

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