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COMTD1 (catechol-O-methyltransferase domain containing 1)

Identity

Alias (NCBI)-
HGNC (Hugo) COMTD1
HGNC Alias symbFLJ23841
LocusID (NCBI) 118881
Atlas_Id 62019
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 75233641 and ends at 75235957 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPATCH8 (17q21.31) / COMTD1 (10q22.2)TCAP (17q12) / COMTD1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)COMTD1   26309
Cards
Entrez_Gene (NCBI)COMTD1    catechol-O-methyltransferase domain containing 1
Aliases
GeneCards (Weizmann)COMTD1
Ensembl hg19 (Hinxton)ENSG00000165644 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165644 [Gene_View]  ENSG00000165644 [Sequence]  chr10:75233641-75235957 [Contig_View]  COMTD1 [Vega]
ICGC DataPortalENSG00000165644
TCGA cBioPortalCOMTD1
AceView (NCBI)COMTD1
Genatlas (Paris)COMTD1
SOURCE (Princeton)COMTD1
Genetics Home Reference (NIH)COMTD1
Genomic and cartography
GoldenPath hg38 (UCSC)COMTD1  -     chr10:75233641-75235957 -  10q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COMTD1  -     10q22.2   [Description]    (hg19-Feb_2009)
GoldenPathCOMTD1 - 10q22.2 [CytoView hg19]  COMTD1 - 10q22.2 [CytoView hg38]
ImmunoBaseENSG00000165644
Genome Data Viewer NCBICOMTD1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK074421 AK290452 AK302283 AY358476 BC023663
RefSeq transcript (Entrez)NM_144589
Consensus coding sequences : CCDS (NCBI)COMTD1
Gene ExpressionCOMTD1 [ NCBI-GEO ]   COMTD1 [ EBI - ARRAY_EXPRESS ]   COMTD1 [ SEEK ]   COMTD1 [ MEM ]
Gene Expression Viewer (FireBrowse)COMTD1 [ Firebrowse - Broad ]
GenevisibleExpression of COMTD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118881
GTEX Portal (Tissue expression)COMTD1
Human Protein AtlasENSG00000165644-COMTD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VU5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VU5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VU5
PhosPhoSitePlusQ86VU5
Domaine pattern : Prosite (Expaxy)SAM_OMT_I (PS51682)   
Domains : Interpro (EBI)SAM-dependent_MTases    SAM_O-MeTrfase   
Domain families : Pfam (Sanger)Methyltransf_3 (PF01596)   
Domain families : Pfam (NCBI)pfam01596   
Conserved Domain (NCBI)COMTD1
PDB (RSDB)2AVD   
PDB Europe2AVD   
PDB (PDBSum)2AVD   
PDB (IMB)2AVD   
Structural Biology KnowledgeBase2AVD   
SCOP (Structural Classification of Proteins)2AVD   
CATH (Classification of proteins structures)2AVD   
SuperfamilyQ86VU5
AlphaFold pdb e-kbQ86VU5   
Human Protein Atlas [tissue]ENSG00000165644-COMTD1 [tissue]
HPRD08678
Protein Interaction databases
DIP (DOE-UCLA)Q86VU5
IntAct (EBI)Q86VU5
BioGRIDCOMTD1
STRING (EMBL)COMTD1
ZODIACCOMTD1
Ontologies - Pathways
QuickGOQ86VU5
Ontology : AmiGOprotein binding  O-methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  integral component of membrane  methylation  
Ontology : EGO-EBIprotein binding  O-methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  integral component of membrane  methylation  
NDEx NetworkCOMTD1
Atlas of Cancer Signalling NetworkCOMTD1
Wikipedia pathwaysCOMTD1
Orthology - Evolution
OrthoDB118881
GeneTree (enSembl)ENSG00000165644
Phylogenetic Trees/Animal Genes : TreeFamCOMTD1
Homologs : HomoloGeneCOMTD1
Homology/Alignments : Family Browser (UCSC)COMTD1
Gene fusions - Rearrangements
Fusion : QuiverCOMTD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOMTD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COMTD1
dbVarCOMTD1
ClinVarCOMTD1
MonarchCOMTD1
1000_GenomesCOMTD1 
Exome Variant ServerCOMTD1
GNOMAD BrowserENSG00000165644
Varsome BrowserCOMTD1
ACMGCOMTD1 variants
VarityQ86VU5
Genomic Variants (DGV)COMTD1 [DGVbeta]
DECIPHERCOMTD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOMTD1 
Mutations
ICGC Data PortalCOMTD1 
TCGA Data PortalCOMTD1 
Broad Tumor PortalCOMTD1
OASIS PortalCOMTD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOMTD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCOMTD1
Mutations and Diseases : HGMDCOMTD1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCOMTD1
DgiDB (Drug Gene Interaction Database)COMTD1
DoCM (Curated mutations)COMTD1
CIViC (Clinical Interpretations of Variants in Cancer)COMTD1
Cancer3DCOMTD1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETCOMTD1
MedgenCOMTD1
Genetic Testing Registry COMTD1
NextProtQ86VU5 [Medical]
GENETestsCOMTD1
Target ValidationCOMTD1
Huge Navigator COMTD1 [HugePedia]
ClinGenCOMTD1
Clinical trials, drugs, therapy
MyCancerGenomeCOMTD1
Protein Interactions : CTDCOMTD1
Pharm GKB GenePA134961676
PharosQ86VU5
Clinical trialCOMTD1
Miscellaneous
canSAR (ICR)COMTD1
HarmonizomeCOMTD1
DataMed IndexCOMTD1
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCOMTD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:46:37 CEST 2021

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