Atlas of Genetics and Cytogenetics in Oncology and Haematology

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COPB1 (coatomer protein complex subunit beta 1)

Identity

Alias_namesCOPB
coatomer protein complex, subunit beta
coatomer protein complex, subunit beta 1
Other alias
HGNC (Hugo) COPB1
LocusID (NCBI) 1315
Atlas_Id 62020
Location 11p15.2  [Link to chromosome band 11p15]
Location_base_pair Starts at 14457503 and ends at 14499895 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COPB1 (11p15.2) / COPB1 (11p15.2)RRAS2 (11p15.2) / COPB1 (11p15.2)SEC22C (3p22.1) / COPB1 (11p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)COPB1   2231
Cards
Entrez_Gene (NCBI)COPB1  1315  coatomer protein complex subunit beta 1
AliasesCOPB
GeneCards (Weizmann)COPB1
Ensembl hg19 (Hinxton)ENSG00000129083 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129083 [Gene_View]  ENSG00000129083 [Sequence]  chr11:14457503-14499895 [Contig_View]  COPB1 [Vega]
ICGC DataPortalENSG00000129083
TCGA cBioPortalCOPB1
AceView (NCBI)COPB1
Genatlas (Paris)COPB1
WikiGenes1315
SOURCE (Princeton)COPB1
Genetics Home Reference (NIH)COPB1
Genomic and cartography
GoldenPath hg38 (UCSC)COPB1  -     chr11:14457503-14499895 -  11p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COPB1  -     11p15.2   [Description]    (hg19-Feb_2009)
GoldenPathCOPB1 - 11p15.2 [CytoView hg19]  COPB1 - 11p15.2 [CytoView hg38]
ImmunoBaseENSG00000129083
Mapping of homologs : NCBICOPB1 [Mapview hg19]  COPB1 [Mapview hg38]
OMIM600959   
Gene and transcription
Genbank (Entrez)AA443270 AF084457 AF111807 AK001203 AK128844
RefSeq transcript (Entrez)NM_001144061 NM_001144062 NM_016451
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COPB1
Cluster EST : UnigeneHs.339278 [ NCBI ]
CGAP (NCI)Hs.339278
Alternative Splicing GalleryENSG00000129083
Gene ExpressionCOPB1 [ NCBI-GEO ]   COPB1 [ EBI - ARRAY_EXPRESS ]   COPB1 [ SEEK ]   COPB1 [ MEM ]
Gene Expression Viewer (FireBrowse)COPB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1315
GTEX Portal (Tissue expression)COPB1
Human Protein AtlasENSG00000129083-COPB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53618   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53618  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53618
Splice isoforms : SwissVarP53618
PhosPhoSitePlusP53618
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Clathrin/coatomer_adapt-like_N    Coatomer_bsu_C    COPB1    COPB1_appendage_platform_dom   
Domain families : Pfam (Sanger)Adaptin_N (PF01602)    Coatamer_beta_C (PF07718)    Coatomer_b_Cpla (PF14806)   
Domain families : Pfam (NCBI)pfam01602    pfam07718    pfam14806   
Conserved Domain (NCBI)COPB1
DMDM Disease mutations1315
Blocks (Seattle)COPB1
SuperfamilyP53618
Human Protein Atlas [tissue]ENSG00000129083-COPB1 [tissue]
Peptide AtlasP53618
HPRD02981
IPIIPI00295851   IPI00982417   IPI00981105   IPI00980624   
Protein Interaction databases
DIP (DOE-UCLA)P53618
IntAct (EBI)P53618
FunCoupENSG00000129083
BioGRIDCOPB1
STRING (EMBL)COPB1
ZODIACCOPB1
Ontologies - Pathways
QuickGOP53618
Ontology : AmiGOGolgi membrane  structural molecule activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  Golgi-associated vesicle  cytosol  cytosol  plasma membrane  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  intra-Golgi vesicle-mediated transport  intra-Golgi vesicle-mediated transport  membrane  viral process  COPI vesicle coat  COPI vesicle coat  transport vesicle  COPI-coated vesicle  secretory granule membrane  intracellular membrane-bounded organelle  neutrophil degranulation  tertiary granule membrane  ficolin-1-rich granule membrane  
Ontology : EGO-EBIGolgi membrane  structural molecule activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  Golgi-associated vesicle  cytosol  cytosol  plasma membrane  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  intra-Golgi vesicle-mediated transport  intra-Golgi vesicle-mediated transport  membrane  viral process  COPI vesicle coat  COPI vesicle coat  transport vesicle  COPI-coated vesicle  secretory granule membrane  intracellular membrane-bounded organelle  neutrophil degranulation  tertiary granule membrane  ficolin-1-rich granule membrane  
NDEx NetworkCOPB1
Atlas of Cancer Signalling NetworkCOPB1
Wikipedia pathwaysCOPB1
Orthology - Evolution
OrthoDB1315
GeneTree (enSembl)ENSG00000129083
Phylogenetic Trees/Animal Genes : TreeFamCOPB1
HOGENOMP53618
Homologs : HomoloGeneCOPB1
Homology/Alignments : Family Browser (UCSC)COPB1
Gene fusions - Rearrangements
Fusion : QuiverCOPB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOPB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COPB1
dbVarCOPB1
ClinVarCOPB1
1000_GenomesCOPB1 
Exome Variant ServerCOPB1
ExAC (Exome Aggregation Consortium)ENSG00000129083
GNOMAD BrowserENSG00000129083
Varsome BrowserCOPB1
Genetic variants : HAPMAP1315
Genomic Variants (DGV)COPB1 [DGVbeta]
DECIPHERCOPB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOPB1 
Mutations
ICGC Data PortalCOPB1 
TCGA Data PortalCOPB1 
Broad Tumor PortalCOPB1
OASIS PortalCOPB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOPB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOPB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch COPB1
DgiDB (Drug Gene Interaction Database)COPB1
DoCM (Curated mutations)COPB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COPB1 (select a term)
intoGenCOPB1
Cancer3DCOPB1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600959   
Orphanet
DisGeNETCOPB1
MedgenCOPB1
Genetic Testing Registry COPB1
NextProtP53618 [Medical]
TSGene1315
GENETestsCOPB1
Target ValidationCOPB1
Huge Navigator COPB1 [HugePedia]
snp3D : Map Gene to Disease1315
BioCentury BCIQCOPB1
ClinGenCOPB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1315
Chemical/Pharm GKB GenePA26747
Clinical trialCOPB1
Miscellaneous
canSAR (ICR)COPB1 (select the gene name)
DataMed IndexCOPB1
Probes
Litterature
PubMed100 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOPB1
EVEXCOPB1
GoPubMedCOPB1
iHOPCOPB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 7 17:14:39 CEST 2019
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