Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

COPS7A (COP9 signalosome subunit 7A)

Identity

Alias (NCBI)CSN7
CSN7A
SGN7a
HGNC (Hugo) COPS7A
HGNC Alias symbCSN7A
HGNC Previous nameCOP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 7A
 COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
LocusID (NCBI) 50813
Atlas_Id 47241
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 6724046 and ends at 6731864 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C9orf3 (9q22.32) / COPS7A (12p13.31)COPS7A (12p13.31) / COPS7A (12p13.31)COPS7A (12p13.31) / GRINA (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COPS7A   16758
Cards
Entrez_Gene (NCBI)COPS7A  50813  COP9 signalosome subunit 7A
AliasesCSN7; CSN7A; SGN7a
GeneCards (Weizmann)COPS7A
Ensembl hg19 (Hinxton)ENSG00000111652 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111652 [Gene_View]  ENSG00000111652 [Sequence]  chr12:6724046-6731864 [Contig_View]  COPS7A [Vega]
ICGC DataPortalENSG00000111652
TCGA cBioPortalCOPS7A
AceView (NCBI)COPS7A
Genatlas (Paris)COPS7A
WikiGenes50813
SOURCE (Princeton)COPS7A
Genetics Home Reference (NIH)COPS7A
Genomic and cartography
GoldenPath hg38 (UCSC)COPS7A  -     chr12:6724046-6731864 +  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COPS7A  -     12p13.31   [Description]    (hg19-Feb_2009)
GoldenPathCOPS7A - 12p13.31 [CytoView hg19]  COPS7A - 12p13.31 [CytoView hg38]
ImmunoBaseENSG00000111652
genome Data Viewer NCBICOPS7A [Mapview hg19]  
OMIM616009   
Gene and transcription
Genbank (Entrez)AB014764 AB033603 AF193844 AF210052 AK001318
RefSeq transcript (Entrez)NM_001164093 NM_001164094 NM_001164095 NM_016319
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COPS7A
Alternative Splicing GalleryENSG00000111652
Gene ExpressionCOPS7A [ NCBI-GEO ]   COPS7A [ EBI - ARRAY_EXPRESS ]   COPS7A [ SEEK ]   COPS7A [ MEM ]
Gene Expression Viewer (FireBrowse)COPS7A [ Firebrowse - Broad ]
GenevisibleExpression of COPS7A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50813
GTEX Portal (Tissue expression)COPS7A
Human Protein AtlasENSG00000111652-COPS7A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBW8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBW8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBW8
Splice isoforms : SwissVarQ9UBW8
PhosPhoSitePlusQ9UBW8
Domaine pattern : Prosite (Expaxy)PCI (PS50250)   
Domains : Interpro (EBI)COPS7A    CSN7_helixI    PCI_dom   
Domain families : Pfam (Sanger)CSN7a_helixI (PF18392)    PCI (PF01399)   
Domain families : Pfam (NCBI)pfam18392    pfam01399   
Domain families : Smart (EMBL)PINT (SM00088)  
Conserved Domain (NCBI)COPS7A
DMDM Disease mutations50813
Blocks (Seattle)COPS7A
PDB (RSDB)4D10    4D18    4WSN   
PDB Europe4D10    4D18    4WSN   
PDB (PDBSum)4D10    4D18    4WSN   
PDB (IMB)4D10    4D18    4WSN   
Structural Biology KnowledgeBase4D10    4D18    4WSN   
SCOP (Structural Classification of Proteins)4D10    4D18    4WSN   
CATH (Classification of proteins structures)4D10    4D18    4WSN   
SuperfamilyQ9UBW8
Human Protein Atlas [tissue]ENSG00000111652-COPS7A [tissue]
Peptide AtlasQ9UBW8
HPRD16736
IPIIPI00301419   IPI01019078   IPI00902665   IPI01010040   IPI01015612   IPI01009347   IPI01014125   IPI01013196   IPI01013606   IPI01012686   IPI01011772   IPI01012201   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBW8
IntAct (EBI)Q9UBW8
FunCoupENSG00000111652
BioGRIDCOPS7A
STRING (EMBL)COPS7A
ZODIACCOPS7A
Ontologies - Pathways
QuickGOQ9UBW8
Ontology : AmiGOprotein deneddylation  nucleotide-excision repair, DNA damage recognition  protein binding  nucleoplasm  nucleoplasm  cytosol  cytosol  transcription-coupled nucleotide-excision repair  COP9 signalosome  COP9 signalosome  COP9 signalosome assembly  viral process  post-translational protein modification  
Ontology : EGO-EBIprotein deneddylation  nucleotide-excision repair, DNA damage recognition  protein binding  nucleoplasm  nucleoplasm  cytosol  cytosol  transcription-coupled nucleotide-excision repair  COP9 signalosome  COP9 signalosome  COP9 signalosome assembly  viral process  post-translational protein modification  
NDEx NetworkCOPS7A
Atlas of Cancer Signalling NetworkCOPS7A
Wikipedia pathwaysCOPS7A
Orthology - Evolution
OrthoDB50813
GeneTree (enSembl)ENSG00000111652
Phylogenetic Trees/Animal Genes : TreeFamCOPS7A
HOGENOMQ9UBW8
Homologs : HomoloGeneCOPS7A
Homology/Alignments : Family Browser (UCSC)COPS7A
Gene fusions - Rearrangements
Fusion : QuiverCOPS7A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOPS7A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COPS7A
dbVarCOPS7A
ClinVarCOPS7A
1000_GenomesCOPS7A 
Exome Variant ServerCOPS7A
GNOMAD BrowserENSG00000111652
Varsome BrowserCOPS7A
Genetic variants : HAPMAP50813
Genomic Variants (DGV)COPS7A [DGVbeta]
DECIPHERCOPS7A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOPS7A 
Mutations
ICGC Data PortalCOPS7A 
TCGA Data PortalCOPS7A 
Broad Tumor PortalCOPS7A
OASIS PortalCOPS7A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOPS7A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCOPS7A
Mutations and Diseases : HGMDCOPS7A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch COPS7A
DgiDB (Drug Gene Interaction Database)COPS7A
DoCM (Curated mutations)COPS7A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COPS7A (select a term)
intoGenCOPS7A
Cancer3DCOPS7A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616009   
Orphanet
DisGeNETCOPS7A
MedgenCOPS7A
Genetic Testing Registry COPS7A
NextProtQ9UBW8 [Medical]
TSGene50813
GENETestsCOPS7A
Target ValidationCOPS7A
Huge Navigator COPS7A [HugePedia]
snp3D : Map Gene to Disease50813
BioCentury BCIQCOPS7A
ClinGenCOPS7A
Clinical trials, drugs, therapy
Protein Interactions : CTD50813
Pharm GKB GenePA26758
Clinical trialCOPS7A
Miscellaneous
canSAR (ICR)COPS7A (select the gene name)
HarmonizomeCOPS7A
DataMed IndexCOPS7A
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOPS7A
EVEXCOPS7A
GoPubMedCOPS7A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:08:43 CEST 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.