Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COPZ1 (coatomer protein complex subunit zeta 1)

Identity

Alias_namesCOPZ
coatomer protein complex, subunit zeta
coatomer protein complex, subunit zeta 1
Alias_symbol (synonym)CGI-120
Other aliasHSPC181
zeta-COP
zeta1-COP
HGNC (Hugo) COPZ1
LocusID (NCBI) 22818
Atlas_Id 52450
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 54325090 and ends at 54351851 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NCOA5 (20q13.12) / COPZ1 (12q13.13)PRRC2B (9q34.13) / COPZ1 (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COPZ1   2243
Cards
Entrez_Gene (NCBI)COPZ1  22818  coatomer protein complex subunit zeta 1
AliasesCGI-120; COPZ; HSPC181; zeta-COP; 
zeta1-COP
GeneCards (Weizmann)COPZ1
Ensembl hg19 (Hinxton)ENSG00000111481 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111481 [Gene_View]  chr12:54325090-54351851 [Contig_View]  COPZ1 [Vega]
ICGC DataPortalENSG00000111481
TCGA cBioPortalCOPZ1
AceView (NCBI)COPZ1
Genatlas (Paris)COPZ1
WikiGenes22818
SOURCE (Princeton)COPZ1
Genetics Home Reference (NIH)COPZ1
Genomic and cartography
GoldenPath hg38 (UCSC)COPZ1  -     chr12:54325090-54351851 +  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COPZ1  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblCOPZ1 - 12q13.13 [CytoView hg19]  COPZ1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBICOPZ1 [Mapview hg19]  COPZ1 [Mapview hg38]
OMIM615472   
Gene and transcription
Genbank (Entrez)AB047848 AF086911 AF151878 AF161529 AK025956
RefSeq transcript (Entrez)NM_001271734 NM_001271735 NM_001271736 NM_016057
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COPZ1
Cluster EST : UnigeneHs.505652 [ NCBI ]
CGAP (NCI)Hs.505652
Alternative Splicing GalleryENSG00000111481
Gene ExpressionCOPZ1 [ NCBI-GEO ]   COPZ1 [ EBI - ARRAY_EXPRESS ]   COPZ1 [ SEEK ]   COPZ1 [ MEM ]
Gene Expression Viewer (FireBrowse)COPZ1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22818
GTEX Portal (Tissue expression)COPZ1
Human Protein AtlasENSG00000111481-COPZ1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61923   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61923  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61923
Splice isoforms : SwissVarP61923
PhosPhoSitePlusP61923
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_S (PS00989)   
Domains : Interpro (EBI)AP_mu_sigma_su    Clathrin_sm-chain_CS    Longin-like_dom   
Domain families : Pfam (Sanger)Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam01217   
Conserved Domain (NCBI)COPZ1
DMDM Disease mutations22818
Blocks (Seattle)COPZ1
PDB (SRS)2HF6    5MC7   
PDB (PDBSum)2HF6    5MC7   
PDB (IMB)2HF6    5MC7   
PDB (RSDB)2HF6    5MC7   
Structural Biology KnowledgeBase2HF6    5MC7   
SCOP (Structural Classification of Proteins)2HF6    5MC7   
CATH (Classification of proteins structures)2HF6    5MC7   
SuperfamilyP61923
Human Protein Atlas [tissue]ENSG00000111481-COPZ1 [tissue]
Peptide AtlasP61923
HPRD16738
IPIIPI00032851   IPI00792095   IPI00791413   IPI01022220   IPI01022067   IPI01021904   IPI01021736   IPI01023034   IPI01022875   IPI01022720   IPI01022559   IPI01020932   IPI01020803   IPI01023037   
Protein Interaction databases
DIP (DOE-UCLA)P61923
IntAct (EBI)P61923
FunCoupENSG00000111481
BioGRIDCOPZ1
STRING (EMBL)COPZ1
ZODIACCOPZ1
Ontologies - Pathways
QuickGOP61923
Ontology : AmiGOGolgi membrane  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  intra-Golgi vesicle-mediated transport  intra-Golgi vesicle-mediated transport  COPI vesicle coat  COPI vesicle coat  transport vesicle  toxin transport  
Ontology : EGO-EBIGolgi membrane  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  intra-Golgi vesicle-mediated transport  intra-Golgi vesicle-mediated transport  COPI vesicle coat  COPI vesicle coat  transport vesicle  toxin transport  
NDEx NetworkCOPZ1
Atlas of Cancer Signalling NetworkCOPZ1
Wikipedia pathwaysCOPZ1
Orthology - Evolution
OrthoDB22818
GeneTree (enSembl)ENSG00000111481
Phylogenetic Trees/Animal Genes : TreeFamCOPZ1
HOVERGENP61923
HOGENOMP61923
Homologs : HomoloGeneCOPZ1
Homology/Alignments : Family Browser (UCSC)COPZ1
Gene fusions - Rearrangements
Tumor Fusion PortalCOPZ1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOPZ1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COPZ1
dbVarCOPZ1
ClinVarCOPZ1
1000_GenomesCOPZ1 
Exome Variant ServerCOPZ1
ExAC (Exome Aggregation Consortium)ENSG00000111481
GNOMAD BrowserENSG00000111481
Genetic variants : HAPMAP22818
Genomic Variants (DGV)COPZ1 [DGVbeta]
DECIPHERCOPZ1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOPZ1 
Mutations
ICGC Data PortalCOPZ1 
TCGA Data PortalCOPZ1 
Broad Tumor PortalCOPZ1
OASIS PortalCOPZ1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOPZ1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOPZ1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch COPZ1
DgiDB (Drug Gene Interaction Database)COPZ1
DoCM (Curated mutations)COPZ1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COPZ1 (select a term)
intoGenCOPZ1
Cancer3DCOPZ1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615472   
Orphanet
DisGeNETCOPZ1
MedgenCOPZ1
Genetic Testing Registry COPZ1
NextProtP61923 [Medical]
TSGene22818
GENETestsCOPZ1
Target ValidationCOPZ1
Huge Navigator COPZ1 [HugePedia]
snp3D : Map Gene to Disease22818
BioCentury BCIQCOPZ1
ClinGenCOPZ1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22818
Chemical/Pharm GKB GenePA26760
Clinical trialCOPZ1
Miscellaneous
canSAR (ICR)COPZ1 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOPZ1
EVEXCOPZ1
GoPubMedCOPZ1
iHOPCOPZ1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:08:38 CET 2017

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