Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COQ7 (coenzyme Q7, hydroxylase)

Identity

Alias (NCBI)CAT5
CLK-1
CLK1
COQ10D8
HGNC (Hugo) COQ7
HGNC Alias symbCLK-1
CAT5
HGNC Alias name5-demethoxyubiquinone hydroxylase
HGNC Previous namecoenzyme Q, 7 (rat, yeast) homolog
 coenzyme Q7 homolog, ubiquinone (yeast)
LocusID (NCBI) 10229
Atlas_Id 62029
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 19067595 and ends at 19080095 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COQ7   2244
Cards
Entrez_Gene (NCBI)COQ7  10229  coenzyme Q7, hydroxylase
AliasesCAT5; CLK-1; CLK1; COQ10D8
GeneCards (Weizmann)COQ7
Ensembl hg19 (Hinxton)ENSG00000167186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167186 [Gene_View]  ENSG00000167186 [Sequence]  chr16:19067595-19080095 [Contig_View]  COQ7 [Vega]
ICGC DataPortalENSG00000167186
TCGA cBioPortalCOQ7
AceView (NCBI)COQ7
Genatlas (Paris)COQ7
WikiGenes10229
SOURCE (Princeton)COQ7
Genetics Home Reference (NIH)COQ7
Genomic and cartography
GoldenPath hg38 (UCSC)COQ7  -     chr16:19067595-19080095 +  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COQ7  -     16p12.3   [Description]    (hg19-Feb_2009)
GoldenPathCOQ7 - 16p12.3 [CytoView hg19]  COQ7 - 16p12.3 [CytoView hg38]
ImmunoBaseENSG00000167186
genome Data Viewer NCBICOQ7 [Mapview hg19]  
OMIM601683   616733   
Gene and transcription
Genbank (Entrez)AF032900 AF098948 AF374413 AI279093 AI424412
RefSeq transcript (Entrez)NM_001190983 NM_001370489 NM_001370490 NM_001370491 NM_001370492 NM_001370493 NM_001370494 NM_001370495 NM_016138
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COQ7
Alternative Splicing GalleryENSG00000167186
Gene ExpressionCOQ7 [ NCBI-GEO ]   COQ7 [ EBI - ARRAY_EXPRESS ]   COQ7 [ SEEK ]   COQ7 [ MEM ]
Gene Expression Viewer (FireBrowse)COQ7 [ Firebrowse - Broad ]
GenevisibleExpression of COQ7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10229
GTEX Portal (Tissue expression)COQ7
Human Protein AtlasENSG00000167186-COQ7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99807   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99807  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99807
Splice isoforms : SwissVarQ99807
PhosPhoSitePlusQ99807
Domains : Interpro (EBI)Ferritin-like_SF    Ubq_synth_Coq7   
Domain families : Pfam (Sanger)COQ7 (PF03232)   
Domain families : Pfam (NCBI)pfam03232   
Conserved Domain (NCBI)COQ7
DMDM Disease mutations10229
Blocks (Seattle)COQ7
SuperfamilyQ99807
Human Protein Atlas [tissue]ENSG00000167186-COQ7 [tissue]
Peptide AtlasQ99807
HPRD03401
IPIIPI00294073   IPI00645720   
Protein Interaction databases
DIP (DOE-UCLA)Q99807
IntAct (EBI)Q99807
FunCoupENSG00000167186
BioGRIDCOQ7
STRING (EMBL)COQ7
ZODIACCOQ7
Ontologies - Pathways
QuickGOQ99807
Ontology : AmiGOprotein binding  nucleus  nucleus  mitochondrial inner membrane  ubiquinone biosynthetic process  ubiquinone biosynthetic process  determination of adult lifespan  2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity  regulation of gene expression  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  extrinsic component of mitochondrial inner membrane  metal ion binding  oxidation-reduction process  regulation of reactive oxygen species metabolic process  
Ontology : EGO-EBIprotein binding  nucleus  nucleus  mitochondrial inner membrane  ubiquinone biosynthetic process  ubiquinone biosynthetic process  determination of adult lifespan  2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity  regulation of gene expression  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  extrinsic component of mitochondrial inner membrane  metal ion binding  oxidation-reduction process  regulation of reactive oxygen species metabolic process  
Pathways : KEGGUbiquinone biosynthesis   
NDEx NetworkCOQ7
Atlas of Cancer Signalling NetworkCOQ7
Wikipedia pathwaysCOQ7
Orthology - Evolution
OrthoDB10229
GeneTree (enSembl)ENSG00000167186
Phylogenetic Trees/Animal Genes : TreeFamCOQ7
HOGENOMQ99807
Homologs : HomoloGeneCOQ7
Homology/Alignments : Family Browser (UCSC)COQ7
Gene fusions - Rearrangements
Fusion : QuiverCOQ7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOQ7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COQ7
dbVarCOQ7
ClinVarCOQ7
1000_GenomesCOQ7 
Exome Variant ServerCOQ7
GNOMAD BrowserENSG00000167186
Varsome BrowserCOQ7
Genetic variants : HAPMAP10229
Genomic Variants (DGV)COQ7 [DGVbeta]
DECIPHERCOQ7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOQ7 
Mutations
ICGC Data PortalCOQ7 
TCGA Data PortalCOQ7 
Broad Tumor PortalCOQ7
OASIS PortalCOQ7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOQ7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCOQ7
Mutations and Diseases : HGMDCOQ7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COQ7
DgiDB (Drug Gene Interaction Database)COQ7
DoCM (Curated mutations)COQ7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COQ7 (select a term)
intoGenCOQ7
Cancer3DCOQ7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601683    616733   
Orphanet
DisGeNETCOQ7
MedgenCOQ7
Genetic Testing Registry COQ7
NextProtQ99807 [Medical]
TSGene10229
GENETestsCOQ7
Target ValidationCOQ7
Huge Navigator COQ7 [HugePedia]
snp3D : Map Gene to Disease10229
BioCentury BCIQCOQ7
ClinGenCOQ7
Clinical trials, drugs, therapy
Protein Interactions : CTD10229
Pharm GKB GenePA26761
Clinical trialCOQ7
Miscellaneous
canSAR (ICR)COQ7 (select the gene name)
HarmonizomeCOQ7
DataMed IndexCOQ7
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOQ7
EVEXCOQ7
GoPubMedCOQ7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:52:08 CEST 2020

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