Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CORO1B (coronin 1B)

Identity

Alias_namescoronin, actin-binding protein, 1B
Alias_symbol (synonym)coronin-2
Other aliasCORONIN-2
HGNC (Hugo) CORO1B
LocusID (NCBI) 57175
Atlas_Id 52893
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67438047 and ends at 67443512 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CORO1B   2253
Cards
Entrez_Gene (NCBI)CORO1B  57175  coronin 1B
AliasesCORONIN-2
GeneCards (Weizmann)CORO1B
Ensembl hg19 (Hinxton)ENSG00000172725 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172725 [Gene_View]  ENSG00000172725 [Sequence]  chr11:67438047-67443512 [Contig_View]  CORO1B [Vega]
ICGC DataPortalENSG00000172725
TCGA cBioPortalCORO1B
AceView (NCBI)CORO1B
Genatlas (Paris)CORO1B
WikiGenes57175
SOURCE (Princeton)CORO1B
Genetics Home Reference (NIH)CORO1B
Genomic and cartography
GoldenPath hg38 (UCSC)CORO1B  -     chr11:67438047-67443512 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CORO1B  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathCORO1B - 11q13.2 [CytoView hg19]  CORO1B - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000172725
Mapping of homologs : NCBICORO1B [Mapview hg19]  CORO1B [Mapview hg38]
OMIM609849   
Gene and transcription
Genbank (Entrez)AK000860 AK295782 AK309267 AK315399 AL162072
RefSeq transcript (Entrez)NM_001018070 NM_020441
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CORO1B
Alternative Splicing GalleryENSG00000172725
Gene ExpressionCORO1B [ NCBI-GEO ]   CORO1B [ EBI - ARRAY_EXPRESS ]   CORO1B [ SEEK ]   CORO1B [ MEM ]
Gene Expression Viewer (FireBrowse)CORO1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57175
GTEX Portal (Tissue expression)CORO1B
Human Protein AtlasENSG00000172725-CORO1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BR76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BR76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BR76
Splice isoforms : SwissVarQ9BR76
PhosPhoSitePlusQ9BR76
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Coro1b    Coronin    DUF1899    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)DUF1899 (PF08953)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam08953    pfam00400   
Domain families : Smart (EMBL)DUF1899 (SM01166)  WD40 (SM00320)  
Conserved Domain (NCBI)CORO1B
DMDM Disease mutations57175
Blocks (Seattle)CORO1B
SuperfamilyQ9BR76
Human Protein Atlas [tissue]ENSG00000172725-CORO1B [tissue]
Peptide AtlasQ9BR76
HPRD16743
IPIIPI00007058   IPI00979820   IPI00867659   IPI00908316   IPI01013525   
Protein Interaction databases
DIP (DOE-UCLA)Q9BR76
IntAct (EBI)Q9BR76
FunCoupENSG00000172725
BioGRIDCORO1B
STRING (EMBL)CORO1B
ZODIACCORO1B
Ontologies - Pathways
QuickGOQ9BR76
Ontology : AmiGOstress fiber  protein binding  cytoplasm  cytosol  actin filament  plasma membrane  focal adhesion  actin filament organization  cell migration  cell migration  lamellipodium  actin cytoskeleton organization  cell leading edge  ruffle organization  regulation of Arp2/3 complex-mediated actin nucleation  negative regulation of Arp2/3 complex-mediated actin nucleation  endothelial cell chemotaxis  endothelial cell chemotaxis  cellular response to platelet-derived growth factor stimulus  wound healing  identical protein binding  cadherin binding  perinuclear region of cytoplasm  actin filament binding  actin filament binding  actin filament binding  actin filament bundle assembly  extracellular exosome  negative regulation of smooth muscle cell chemotaxis  Arp2/3 complex binding  Arp2/3 complex binding  cell periphery  actin filament branching  protein localization to cell leading edge  positive regulation of lamellipodium morphogenesis  
Ontology : EGO-EBIstress fiber  protein binding  cytoplasm  cytosol  actin filament  plasma membrane  focal adhesion  actin filament organization  cell migration  cell migration  lamellipodium  actin cytoskeleton organization  cell leading edge  ruffle organization  regulation of Arp2/3 complex-mediated actin nucleation  negative regulation of Arp2/3 complex-mediated actin nucleation  endothelial cell chemotaxis  endothelial cell chemotaxis  cellular response to platelet-derived growth factor stimulus  wound healing  identical protein binding  cadherin binding  perinuclear region of cytoplasm  actin filament binding  actin filament binding  actin filament binding  actin filament bundle assembly  extracellular exosome  negative regulation of smooth muscle cell chemotaxis  Arp2/3 complex binding  Arp2/3 complex binding  cell periphery  actin filament branching  protein localization to cell leading edge  positive regulation of lamellipodium morphogenesis  
NDEx NetworkCORO1B
Atlas of Cancer Signalling NetworkCORO1B
Wikipedia pathwaysCORO1B
Orthology - Evolution
OrthoDB57175
GeneTree (enSembl)ENSG00000172725
Phylogenetic Trees/Animal Genes : TreeFamCORO1B
HOGENOMQ9BR76
Homologs : HomoloGeneCORO1B
Homology/Alignments : Family Browser (UCSC)CORO1B
Gene fusions - Rearrangements
Fusion : QuiverCORO1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCORO1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CORO1B
dbVarCORO1B
ClinVarCORO1B
1000_GenomesCORO1B 
Exome Variant ServerCORO1B
ExAC (Exome Aggregation Consortium)ENSG00000172725
GNOMAD BrowserENSG00000172725
Varsome BrowserCORO1B
Genetic variants : HAPMAP57175
Genomic Variants (DGV)CORO1B [DGVbeta]
DECIPHERCORO1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCORO1B 
Mutations
ICGC Data PortalCORO1B 
TCGA Data PortalCORO1B 
Broad Tumor PortalCORO1B
OASIS PortalCORO1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCORO1B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCORO1B
Mutations and Diseases : HGMDCORO1B
BioMutasearch CORO1B
DgiDB (Drug Gene Interaction Database)CORO1B
DoCM (Curated mutations)CORO1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CORO1B (select a term)
intoGenCORO1B
Cancer3DCORO1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609849   
Orphanet
DisGeNETCORO1B
MedgenCORO1B
Genetic Testing Registry CORO1B
NextProtQ9BR76 [Medical]
TSGene57175
GENETestsCORO1B
Target ValidationCORO1B
Huge Navigator CORO1B [HugePedia]
snp3D : Map Gene to Disease57175
BioCentury BCIQCORO1B
ClinGenCORO1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57175
Chemical/Pharm GKB GenePA26769
Clinical trialCORO1B
Miscellaneous
canSAR (ICR)CORO1B (select the gene name)
HarmonizomeCORO1B
DataMed IndexCORO1B
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCORO1B
EVEXCORO1B
GoPubMedCORO1B
iHOPCORO1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 10 12:11:14 CEST 2020
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