CORO1B (coronin 1B)

2012-09-01  

Identity

HGNC
LOCATION
11q13.2
LOCUSID
ALIAS
CORONIN-2

Other Information

Locus ID:

NCBI: 57175
MIM: 609849
HGNC: 2253
Ensembl: ENSG00000172725

Variants:

dbSNP: 57175
ClinVar: 57175
TCGA: ENSG00000172725
COSMIC: CORO1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172725ENST00000341356Q9BR76
ENSG00000172725ENST00000341356A0A024R5K1
ENSG00000172725ENST00000393893Q9BR76
ENSG00000172725ENST00000393893A0A024R5K1
ENSG00000172725ENST00000537042F5H390
ENSG00000172725ENST00000545016F5H0D2
ENSG00000172725ENST00000616321A0A087WW53
ENSG00000172725ENST00000627576F5H390

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
173505762007Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge.104
160271582005Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility.47
270468322016Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions.24
225630752012Novel mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility.12
99158401999Isolation, cloning, and characterization of a new mammalian coronin family member, coroninse, which is regulated within the protein kinase C signaling pathway.7
236675612013Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction.6
276509612016Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II.4
275920292016Coronin 1B serine 2 phosphorylation by p38α is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells.2
286259212017Binding of coronin 1B to TβRI negatively regulates the TGFβ1 signaling pathway.0

Citation

Dessen P

CORO1B (coronin 1B)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52893/coro1b