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CORO1C (coronin 1C)

Identity

Alias_namescoronin
Alias_symbol (synonym)coronin-3
HCRNN4
Other alias
HGNC (Hugo) CORO1C
LocusID (NCBI) 23603
Atlas_Id 51722
Location 12q24.11  [Link to chromosome band 12q24]
Location_base_pair Starts at 108645111 and ends at 108702998 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CORO1C (12q24.11) / ANKS1B (12q23.1)CORO1C (12q24.11) / C12orf42 (12q23.2)CORO1C (12q24.11) / PPIA (7p13)
CORO1C (12q24.11) / ZNF664 (12q24.31)HLA-DQB1 (6p21.32) / CORO1C (12q24.11)NAALADL2 (3q26.31) / CORO1C (12q24.11)
SART3 (12q23.3) / CORO1C (12q24.11)TBC1D9 (4q31.21) / CORO1C (12q24.11)CORO1C 12q24.11 / ANKS1B 12q23.1
CORO1C 12q24.11 / C12orf42 12q23.2CORO1C 12q24.11 / ZNF664 12q24.31SART3 12q23.3 / CORO1C 12q24.11
TBC1D9 4q31.21 / CORO1C 12q24.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CORO1C   2254
Cards
Entrez_Gene (NCBI)CORO1C  23603  coronin 1C
AliasesHCRNN4
GeneCards (Weizmann)CORO1C
Ensembl hg19 (Hinxton)ENSG00000110880 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110880 [Gene_View]  chr12:108645111-108702998 [Contig_View]  CORO1C [Vega]
ICGC DataPortalENSG00000110880
TCGA cBioPortalCORO1C
AceView (NCBI)CORO1C
Genatlas (Paris)CORO1C
WikiGenes23603
SOURCE (Princeton)CORO1C
Genetics Home Reference (NIH)CORO1C
Genomic and cartography
GoldenPath hg38 (UCSC)CORO1C  -     chr12:108645111-108702998 -  12q24.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CORO1C  -     12q24.11   [Description]    (hg19-Feb_2009)
EnsemblCORO1C - 12q24.11 [CytoView hg19]  CORO1C - 12q24.11 [CytoView hg38]
Mapping of homologs : NCBICORO1C [Mapview hg19]  CORO1C [Mapview hg38]
OMIM605269   
Gene and transcription
Genbank (Entrez)AB030656 AB209909 AK023205 AK096363 AK223073
RefSeq transcript (Entrez)NM_001105237 NM_001276471 NM_014325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CORO1C
Cluster EST : UnigeneHs.330384 [ NCBI ]
CGAP (NCI)Hs.330384
Alternative Splicing GalleryENSG00000110880
Gene ExpressionCORO1C [ NCBI-GEO ]   CORO1C [ EBI - ARRAY_EXPRESS ]   CORO1C [ SEEK ]   CORO1C [ MEM ]
Gene Expression Viewer (FireBrowse)CORO1C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23603
GTEX Portal (Tissue expression)CORO1C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULV4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULV4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULV4
Splice isoforms : SwissVarQ9ULV4
PhosPhoSitePlusQ9ULV4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)CORO1C    Coronin    DUF1899    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)DUF1899 (PF08953)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam08953    pfam00400   
Domain families : Smart (EMBL)DUF1899 (SM01166)  WD40 (SM00320)  
Conserved Domain (NCBI)CORO1C
DMDM Disease mutations23603
Blocks (Seattle)CORO1C
SuperfamilyQ9ULV4
Human Protein AtlasENSG00000110880
Peptide AtlasQ9ULV4
HPRD09244
IPIIPI00943173   IPI00867509   IPI01011988   IPI01022477   IPI01022652   IPI01022161   IPI01021235   IPI01021228   IPI01021090   IPI01020922   IPI01022107   IPI01021948   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULV4
IntAct (EBI)Q9ULV4
FunCoupENSG00000110880
BioGRIDCORO1C
STRING (EMBL)CORO1C
ZODIACCORO1C
Ontologies - Pathways
QuickGOQ9ULV4
Ontology : AmiGOneural crest cell migration  regulation of protein phosphorylation  negative regulation of protein phosphorylation  protein binding  cytoplasm  focal adhesion  focal adhesion  phagocytosis  signal transduction  regulation of epithelial cell migration  negative regulation of epithelial cell migration  regulation of fibroblast migration  actin cytoskeleton  lateral plasma membrane  flotillin complex  lamellipodium  actin cytoskeleton organization  vesicle  negative regulation of protein kinase activity by regulation of protein phosphorylation  establishment of protein localization  Rac GTPase binding  actin filament binding  regulation of focal adhesion assembly  negative regulation of focal adhesion assembly  activation of GTPase activity  regulation of substrate adhesion-dependent cell spreading  negative regulation of substrate adhesion-dependent cell spreading  regulation of ruffle assembly  positive regulation of lamellipodium morphogenesis  
Ontology : EGO-EBIneural crest cell migration  regulation of protein phosphorylation  negative regulation of protein phosphorylation  protein binding  cytoplasm  focal adhesion  focal adhesion  phagocytosis  signal transduction  regulation of epithelial cell migration  negative regulation of epithelial cell migration  regulation of fibroblast migration  actin cytoskeleton  lateral plasma membrane  flotillin complex  lamellipodium  actin cytoskeleton organization  vesicle  negative regulation of protein kinase activity by regulation of protein phosphorylation  establishment of protein localization  Rac GTPase binding  actin filament binding  regulation of focal adhesion assembly  negative regulation of focal adhesion assembly  activation of GTPase activity  regulation of substrate adhesion-dependent cell spreading  negative regulation of substrate adhesion-dependent cell spreading  regulation of ruffle assembly  positive regulation of lamellipodium morphogenesis  
NDEx NetworkCORO1C
Atlas of Cancer Signalling NetworkCORO1C
Wikipedia pathwaysCORO1C
Orthology - Evolution
OrthoDB23603
GeneTree (enSembl)ENSG00000110880
Phylogenetic Trees/Animal Genes : TreeFamCORO1C
HOVERGENQ9ULV4
HOGENOMQ9ULV4
Homologs : HomoloGeneCORO1C
Homology/Alignments : Family Browser (UCSC)CORO1C
Gene fusions - Rearrangements
Fusion : MitelmanCORO1C/ANKS1B [12q24.11/12q23.1]  
Fusion : MitelmanCORO1C/C12orf42 [12q24.11/12q23.2]  [t(12;12)(q23;q24)]  
Fusion : MitelmanCORO1C/ZNF664 [12q24.11/12q24.31]  [t(12;12)(q24;q24)]  
Fusion : MitelmanSART3/CORO1C [12q23.3/12q24.11]  [t(12;12)(q13;q24)]  
Fusion : MitelmanTBC1D9/CORO1C [4q31.21/12q24.11]  [t(4;12)(q31;q24)]  
Fusion: TCGACORO1C 12q24.11 ANKS1B 12q23.1 BRCA
Fusion: TCGACORO1C 12q24.11 C12orf42 12q23.2 BRCA
Fusion: TCGACORO1C 12q24.11 ZNF664 12q24.31 LGG
Fusion: TCGASART3 12q23.3 CORO1C 12q24.11 LUAD
Fusion: TCGATBC1D9 4q31.21 CORO1C 12q24.11 BRCA
Fusion Cancer (Beijing)CORO1C [12q24.11]  -  PPIA [7p13]  [FUSC001347]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCORO1C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CORO1C
dbVarCORO1C
ClinVarCORO1C
1000_GenomesCORO1C 
Exome Variant ServerCORO1C
ExAC (Exome Aggregation Consortium)CORO1C (select the gene name)
Genetic variants : HAPMAP23603
Genomic Variants (DGV)CORO1C [DGVbeta]
DECIPHERCORO1C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCORO1C 
Mutations
ICGC Data PortalCORO1C 
TCGA Data PortalCORO1C 
Broad Tumor PortalCORO1C
OASIS PortalCORO1C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCORO1C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCORO1C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CORO1C
DgiDB (Drug Gene Interaction Database)CORO1C
DoCM (Curated mutations)CORO1C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CORO1C (select a term)
intoGenCORO1C
Cancer3DCORO1C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605269   
Orphanet
MedgenCORO1C
Genetic Testing Registry CORO1C
NextProtQ9ULV4 [Medical]
TSGene23603
GENETestsCORO1C
Target ValidationCORO1C
Huge Navigator CORO1C [HugePedia]
snp3D : Map Gene to Disease23603
BioCentury BCIQCORO1C
ClinGenCORO1C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23603
Chemical/Pharm GKB GenePA26770
Clinical trialCORO1C
Miscellaneous
canSAR (ICR)CORO1C (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCORO1C
EVEXCORO1C
GoPubMedCORO1C
iHOPCORO1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:58:25 CEST 2017

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