CORO7 (coronin 7)

2014-08-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
0610011B16Rik,CRN7,POD1
FUSION GENES

Other Information

Locus ID:

NCBI: 79585
MIM: 611668
HGNC: 26161
Ensembl: ENSG00000262246

Variants:

dbSNP: 79585
ClinVar: 79585
TCGA: ENSG00000262246
COSMIC: CORO7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000262246ENST00000251166P57737
ENSG00000262246ENST00000537233P57737
ENSG00000262246ENST00000570645I3L423
ENSG00000262246ENST00000570779I3L442
ENSG00000262246ENST00000570928I3L359
ENSG00000262246ENST00000571052I3L1T5
ENSG00000262246ENST00000571059I3L2Y6
ENSG00000262246ENST00000571227I3L0Z7
ENSG00000262246ENST00000571756I3L1G9
ENSG00000262246ENST00000572044I3L0X8
ENSG00000262246ENST00000572153I3L482
ENSG00000262246ENST00000572549I3L212
ENSG00000262246ENST00000572898I3L1M1
ENSG00000262246ENST00000573165I3L258
ENSG00000262246ENST00000574025P57737
ENSG00000262246ENST00000574311E7EP81
ENSG00000262246ENST00000575038I3NI06
ENSG00000262246ENST00000575850I3L426
ENSG00000262246ENST00000576051I3L2S7
ENSG00000262246ENST00000576437I3L1Z1
ENSG00000262246ENST00000576637I3L351

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447197Attention Deficit Disorder with HyperactivityDiseaseClinicalAnnotation, VariantAnnotationassociatedPD29382897
PA450464methylphenidateChemicalClinicalAnnotation, VariantAnnotationassociatedPD29382897

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
247685392014K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking.34
153279922004Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.19
169057712006Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.9
185810492008Molecular mechanism underlying the association of Coronin-7 with Golgi membranes.3
258875382015Implication of coronin 7 in body weight regulation in humans, mice and flies.2
211307662011Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.0

Citation

Dessen P

CORO7 (coronin 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54230/coro7