Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COTL1 (coactosin-like F-actin binding protein 1)

Identity

Other namesCLP
HGNC (Hugo) COTL1
LocusID (NCBI) 23406
Location 16q24.1
Location_base_pair Starts at 84599204 and ends at 84651702 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)COTL1   18304
Cards
Entrez_Gene (NCBI)COTL1  23406  coactosin-like F-actin binding protein 1
GeneCards (Weizmann)COTL1
Ensembl (Hinxton)ENSG00000103187 [Gene_View]  chr16:84599204-84651702 [Contig_View]  COTL1 [Vega]
ICGC DataPortalENSG00000103187
cBioPortalCOTL1
AceView (NCBI)COTL1
Genatlas (Paris)COTL1
WikiGenes23406
SOURCE (Princeton)NM_021149
Genomic and cartography
GoldenPath (UCSC)COTL1  -  16q24.1   chr16:84599204-84651702 -  16q24.1   [Description]    (hg19-Feb_2009)
EnsemblCOTL1 - 16q24.1 [CytoView]
Mapping of homologs : NCBICOTL1 [Mapview]
OMIM606748   
Gene and transcription
Genbank (Entrez)AK026033 AK093712 AK125645 AK127352 AK315675
RefSeq transcript (Entrez)NM_021149
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010498 NW_001838328 NW_004929402
Consensus coding sequences : CCDS (NCBI)COTL1
Cluster EST : UnigeneHs.289092 [ NCBI ]
CGAP (NCI)Hs.289092
Alternative Splicing : Fast-db (Paris)GSHG0012033
Alternative Splicing GalleryENSG00000103187
Gene ExpressionCOTL1 [ NCBI-GEO ]     COTL1 [ SEEK ]   COTL1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14019 (Uniprot)
NextProtQ14019  [Medical]
With graphics : InterProQ14019
Splice isoforms : SwissVarQ14019 (Swissvar)
Domaine pattern : Prosite (Expaxy)ADF_H (PS51263)   
Domains : Interpro (EBI)ADF-H [organisation]   ADF-H/Gelsolin-like_dom [organisation]  
Related proteins : CluSTrQ14019
Domain families : Pfam (Sanger)Cofilin_ADF (PF00241)   
Domain families : Pfam (NCBI)pfam00241   
Domain families : Smart (EMBL)ADF (SM00102)  
DMDM Disease mutations23406
Blocks (Seattle)Q14019
PDB (SRS)1T2L    1T3X    1T3Y    1TMW    1VFQ    1WNJ   
PDB (PDBSum)1T2L    1T3X    1T3Y    1TMW    1VFQ    1WNJ   
PDB (IMB)1T2L    1T3X    1T3Y    1TMW    1VFQ    1WNJ   
PDB (RSDB)1T2L    1T3X    1T3Y    1TMW    1VFQ    1WNJ   
Human Protein AtlasENSG00000103187 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ14019
HPRD09482
IPIIPI00017704   IPI00921562   
Protein Interaction databases
DIP (DOE-UCLA)Q14019
IntAct (EBI)Q14019
FunCoupENSG00000103187
BioGRIDCOTL1
InParanoidQ14019
Interologous Interaction database Q14019
IntegromeDBCOTL1
STRING (EMBL)COTL1
Ontologies - Pathways
Ontology : AmiGOactin binding  protein binding  cytoplasm  cytoskeleton  biological_process  enzyme binding  nuclear membrane  defense response to fungus  extracellular vesicular exosome  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  cytoskeleton  biological_process  enzyme binding  nuclear membrane  defense response to fungus  extracellular vesicular exosome  
Protein Interaction DatabaseCOTL1
Wikipedia pathwaysCOTL1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)COTL1
snp3D : Map Gene to Disease23406
SNP (GeneSNP Utah)COTL1
SNP : HGBaseCOTL1
Genetic variants : HAPMAPCOTL1
Exome VariantCOTL1
1000_GenomesCOTL1 
ICGC programENSG00000103187 
Somatic Mutations in Cancer : COSMICCOTL1 
CONAN: Copy Number AnalysisCOTL1 
Mutations and Diseases : HGMDCOTL1
Mutations and Diseases : intOGenCOTL1
Genomic VariantsCOTL1  COTL1 [DGVbeta]
dbVarCOTL1
ClinVarCOTL1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM606748   
MedgenCOTL1
GENETestsCOTL1
Disease Genetic AssociationCOTL1
Huge Navigator COTL1 [HugePedia]  COTL1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCOTL1
Homology/Alignments : Family Browser (UCSC)COTL1
Phylogenetic Trees/Animal Genes : TreeFamCOTL1
Chemical/Protein Interactions : CTD23406
Chemical/Pharm GKB GenePA38522
Clinical trialCOTL1
Cancer Resource (Charite)ENSG00000103187
Other databases
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
CoreMineCOTL1
iHOPCOTL1
OncoSearchCOTL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:42:57 CEST 2014

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