Atlas of Genetics and Cytogenetics in Oncology and Haematology

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COX15 (COX15, cytochrome c oxidase assembly homolog)

Identity

Alias_namesCOX15 (yeast) homolog
Alias_symbol (synonym)CEMCOX2
Other alias
HGNC (Hugo) COX15
LocusID (NCBI) 1355
Atlas_Id 47442
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 99710868 and ends at 99732666 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD44 (11p13) / COX15 (10q24.2)COX15 (10q24.2) / TRAPPC4 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)COX15   2263
LRG (Locus Reference Genomic)LRG_406
Cards
Entrez_Gene (NCBI)COX15  1355  COX15, cytochrome c oxidase assembly homolog
AliasesCEMCOX2
GeneCards (Weizmann)COX15
Ensembl hg19 (Hinxton)ENSG00000014919 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000014919 [Gene_View]  ENSG00000014919 [Sequence]  chr10:99710868-99732666 [Contig_View]  COX15 [Vega]
ICGC DataPortalENSG00000014919
TCGA cBioPortalCOX15
AceView (NCBI)COX15
Genatlas (Paris)COX15
WikiGenes1355
SOURCE (Princeton)COX15
Genetics Home Reference (NIH)COX15
Genomic and cartography
GoldenPath hg38 (UCSC)COX15  -     chr10:99710868-99732666 -  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COX15  -     10q24.2   [Description]    (hg19-Feb_2009)
EnsemblCOX15 - 10q24.2 [CytoView hg19]  COX15 - 10q24.2 [CytoView hg38]
Mapping of homologs : NCBICOX15 [Mapview hg19]  COX15 [Mapview hg38]
OMIM256000   603646   615119   
Gene and transcription
Genbank (Entrez)AF026850 AF044323 AI760159 AK291654 AK298864
RefSeq transcript (Entrez)NM_001320974 NM_001320975 NM_001320976 NM_004376 NM_078470
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COX15
Cluster EST : UnigeneHs.28326 [ NCBI ]
CGAP (NCI)Hs.28326
Alternative Splicing GalleryENSG00000014919
Gene ExpressionCOX15 [ NCBI-GEO ]   COX15 [ EBI - ARRAY_EXPRESS ]   COX15 [ SEEK ]   COX15 [ MEM ]
Gene Expression Viewer (FireBrowse)COX15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1355
GTEX Portal (Tissue expression)COX15
Human Protein AtlasENSG00000014919-COX15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7KZN9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7KZN9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7KZN9
Splice isoforms : SwissVarQ7KZN9
PhosPhoSitePlusQ7KZN9
Domains : Interpro (EBI)COX15/CtaA_fam    HemeA_Synthase_type2    Peptidase_S1_PA   
Domain families : Pfam (Sanger)COX15-CtaA (PF02628)   
Domain families : Pfam (NCBI)pfam02628   
Conserved Domain (NCBI)COX15
DMDM Disease mutations1355
Blocks (Seattle)COX15
SuperfamilyQ7KZN9
Human Protein Atlas [tissue]ENSG00000014919-COX15 [tissue]
Peptide AtlasQ7KZN9
HPRD04707
IPIIPI00419869   IPI00455190   
Protein Interaction databases
DIP (DOE-UCLA)Q7KZN9
IntAct (EBI)Q7KZN9
FunCoupENSG00000014919
BioGRIDCOX15
STRING (EMBL)COX15
ZODIACCOX15
Ontologies - Pathways
QuickGOQ7KZN9
Ontology : AmiGOcytochrome-c oxidase activity  cytochrome-c oxidase activity  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  heme biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  respiratory gaseous exchange  respiratory chain complex IV assembly  integral component of membrane  oxidoreductase activity, acting on the CH-CH group of donors  cellular respiration  oxidation-reduction process  cytochrome complex  hydrogen ion transmembrane transport  
Ontology : EGO-EBIcytochrome-c oxidase activity  cytochrome-c oxidase activity  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  heme biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  respiratory gaseous exchange  respiratory chain complex IV assembly  integral component of membrane  oxidoreductase activity, acting on the CH-CH group of donors  cellular respiration  oxidation-reduction process  cytochrome complex  hydrogen ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation   
NDEx NetworkCOX15
Atlas of Cancer Signalling NetworkCOX15
Wikipedia pathwaysCOX15
Orthology - Evolution
OrthoDB1355
GeneTree (enSembl)ENSG00000014919
Phylogenetic Trees/Animal Genes : TreeFamCOX15
HOVERGENQ7KZN9
HOGENOMQ7KZN9
Homologs : HomoloGeneCOX15
Homology/Alignments : Family Browser (UCSC)COX15
Gene fusions - Rearrangements
Fusion : QuiverCOX15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOX15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COX15
dbVarCOX15
ClinVarCOX15
1000_GenomesCOX15 
Exome Variant ServerCOX15
ExAC (Exome Aggregation Consortium)ENSG00000014919
GNOMAD BrowserENSG00000014919
Genetic variants : HAPMAP1355
Genomic Variants (DGV)COX15 [DGVbeta]
DECIPHERCOX15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOX15 
Mutations
ICGC Data PortalCOX15 
TCGA Data PortalCOX15 
Broad Tumor PortalCOX15
OASIS PortalCOX15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOX15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOX15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COX15
DgiDB (Drug Gene Interaction Database)COX15
DoCM (Curated mutations)COX15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COX15 (select a term)
intoGenCOX15
Cancer3DCOX15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM256000    603646    615119   
Orphanet19814    3379   
DisGeNETCOX15
MedgenCOX15
Genetic Testing Registry COX15
NextProtQ7KZN9 [Medical]
TSGene1355
GENETestsCOX15
Target ValidationCOX15
Huge Navigator COX15 [HugePedia]
snp3D : Map Gene to Disease1355
BioCentury BCIQCOX15
ClinGenCOX15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1355
Chemical/Pharm GKB GenePA26779
Clinical trialCOX15
Miscellaneous
canSAR (ICR)COX15 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOX15
EVEXCOX15
GoPubMedCOX15
iHOPCOX15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:20:33 CEST 2018
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