Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COX15 (cytochrome c oxidase assembly homolog COX15)

Identity

Alias (NCBI)CEMCOX2
HGNC (Hugo) COX15
HGNC Alias symbCEMCOX2
HGNC Previous nameCOX15 (yeast) homolog, cytochrome c oxidase assembly protein
 COX15, cytochrome c oxidase assembly homolog
LocusID (NCBI) 1355
Atlas_Id 47442
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 99710868 and ends at 99732127 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD44 (11p13) / COX15 (10q24.2)COX15 (10q24.2) / TRAPPC4 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)COX15   2263
LRG (Locus Reference Genomic)LRG_406
Cards
Entrez_Gene (NCBI)COX15    cytochrome c oxidase assembly homolog COX15
AliasesCEMCOX2
GeneCards (Weizmann)COX15
Ensembl hg19 (Hinxton)ENSG00000014919 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000014919 [Gene_View]  ENSG00000014919 [Sequence]  chr10:99710868-99732127 [Contig_View]  COX15 [Vega]
ICGC DataPortalENSG00000014919
TCGA cBioPortalCOX15
AceView (NCBI)COX15
Genatlas (Paris)COX15
SOURCE (Princeton)COX15
Genetics Home Reference (NIH)COX15
Genomic and cartography
GoldenPath hg38 (UCSC)COX15  -     chr10:99710868-99732127 -  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COX15  -     10q24.2   [Description]    (hg19-Feb_2009)
GoldenPathCOX15 - 10q24.2 [CytoView hg19]  COX15 - 10q24.2 [CytoView hg38]
ImmunoBaseENSG00000014919
genome Data Viewer NCBICOX15 [Mapview hg19]  
OMIM256000   603646   615119   
Gene and transcription
Genbank (Entrez)AF026850 AF044323 AI760159 AK291654 AK298864
RefSeq transcript (Entrez)NM_001320974 NM_001320975 NM_001320976 NM_001372024 NM_001372025 NM_001372026 NM_001372027 NM_001372028 NM_004376 NM_078470
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COX15
Alternative Splicing GalleryENSG00000014919
Gene ExpressionCOX15 [ NCBI-GEO ]   COX15 [ EBI - ARRAY_EXPRESS ]   COX15 [ SEEK ]   COX15 [ MEM ]
Gene Expression Viewer (FireBrowse)COX15 [ Firebrowse - Broad ]
GenevisibleExpression of COX15 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1355
GTEX Portal (Tissue expression)COX15
Human Protein AtlasENSG00000014919-COX15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7KZN9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7KZN9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7KZN9
Splice isoforms : SwissVarQ7KZN9
PhosPhoSitePlusQ7KZN9
Domains : Interpro (EBI)COX15/CtaA_fam    HemeA_Synthase_type2    Peptidase_S1_PA   
Domain families : Pfam (Sanger)COX15-CtaA (PF02628)   
Domain families : Pfam (NCBI)pfam02628   
Conserved Domain (NCBI)COX15
Blocks (Seattle)COX15
SuperfamilyQ7KZN9
Human Protein Atlas [tissue]ENSG00000014919-COX15 [tissue]
Peptide AtlasQ7KZN9
HPRD04707
IPIIPI00419869   IPI00455190   
Protein Interaction databases
DIP (DOE-UCLA)Q7KZN9
IntAct (EBI)Q7KZN9
BioGRIDCOX15
STRING (EMBL)COX15
ZODIACCOX15
Ontologies - Pathways
QuickGOQ7KZN9
Ontology : AmiGOcytochrome-c oxidase activity  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  heme biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  respiratory gaseous exchange  respiratory chain complex IV assembly  integral component of membrane  oxidoreductase activity, acting on the CH-CH group of donors  oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor  heme binding  cellular respiration  oxidation-reduction process  molecular adaptor activity  cytochrome complex  proton transmembrane transport  
Ontology : EGO-EBIcytochrome-c oxidase activity  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  heme biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  heme a biosynthetic process  respiratory gaseous exchange  respiratory chain complex IV assembly  integral component of membrane  oxidoreductase activity, acting on the CH-CH group of donors  oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor  heme binding  cellular respiration  oxidation-reduction process  molecular adaptor activity  cytochrome complex  proton transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Porphyrin and chlorophyll metabolism   
NDEx NetworkCOX15
Atlas of Cancer Signalling NetworkCOX15
Wikipedia pathwaysCOX15
Orthology - Evolution
OrthoDB1355
GeneTree (enSembl)ENSG00000014919
Phylogenetic Trees/Animal Genes : TreeFamCOX15
HOGENOMQ7KZN9
Homologs : HomoloGeneCOX15
Homology/Alignments : Family Browser (UCSC)COX15
Gene fusions - Rearrangements
Fusion : QuiverCOX15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOX15 [hg38]
dbVarCOX15
ClinVarCOX15
MonarchCOX15
1000_GenomesCOX15 
Exome Variant ServerCOX15
GNOMAD BrowserENSG00000014919
Varsome BrowserCOX15
Genomic Variants (DGV)COX15 [DGVbeta]
DECIPHERCOX15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOX15 
Mutations
ICGC Data PortalCOX15 
TCGA Data PortalCOX15 
Broad Tumor PortalCOX15
OASIS PortalCOX15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOX15  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCOX15
Mutations and Diseases : HGMDCOX15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COX15
DgiDB (Drug Gene Interaction Database)COX15
DoCM (Curated mutations)COX15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COX15 (select a term)
intoGenCOX15
Cancer3DCOX15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM256000    603646    615119   
Orphanet19814    3379   
DisGeNETCOX15
MedgenCOX15
Genetic Testing Registry COX15
NextProtQ7KZN9 [Medical]
GENETestsCOX15
Target ValidationCOX15
Huge Navigator COX15 [HugePedia]
ClinGenCOX15
Clinical trials, drugs, therapy
MyCancerGenomeCOX15
Protein Interactions : CTD
Pharm GKB GenePA26779
PharosQ7KZN9
Clinical trialCOX15
Miscellaneous
canSAR (ICR)COX15 (select the gene name)
HarmonizomeCOX15
DataMed IndexCOX15
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCOX15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:11:04 CET 2021

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