| Nomenclature |
|---|
| HGNC (Hugo) | COX15 2263 |
| LRG (Locus Reference Genomic) | LRG_406 |
| Cards |
|---|
| Entrez_Gene (NCBI) | COX15 1355 cytochrome c oxidase assembly homolog COX15 |
| Aliases | CEMCOX2 |
| GeneCards (Weizmann) | COX15 |
| Ensembl hg19 (Hinxton) | ENSG00000014919 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000014919 [Gene_View] ENSG00000014919 [Sequence] chr10:99710868-99732666 [Contig_View] COX15 [Vega] |
| ICGC DataPortal | ENSG00000014919 |
| TCGA cBioPortal | COX15 |
| AceView (NCBI) | COX15 |
| Genatlas (Paris) | COX15 |
| WikiGenes | 1355 |
| SOURCE (Princeton) | COX15 |
| Genetics Home Reference (NIH) | COX15 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | COX15 - chr10:99710868-99732666 - 10q24.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | COX15 - 10q24.2 [Description] (hg19-Feb_2009) |
| Ensembl | COX15 - 10q24.2 [CytoView hg19] COX15 - 10q24.2 [CytoView hg38] |
| Mapping of homologs : NCBI | COX15 [Mapview hg19] COX15 [Mapview hg38] |
| OMIM | 256000 603646 615119 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF026850 AF044323 AI760159 AK291654 AK298864 |
| RefSeq transcript (Entrez) | NM_001320974 NM_001320975 NM_001320976 NM_004376 NM_078470 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | COX15 |
| Cluster EST : Unigene | Hs.28326 [ NCBI ] |
| CGAP (NCI) | Hs.28326 |
| Alternative Splicing Gallery | ENSG00000014919 |
| Gene Expression | COX15 [ NCBI-GEO ] COX15 [ EBI - ARRAY_EXPRESS ]
COX15 [ SEEK ] COX15 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | COX15 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1355 |
| GTEX Portal (Tissue expression) | COX15 |
| Human Protein Atlas | ENSG00000014919-COX15 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q7KZN9 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q7KZN9 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q7KZN9 |
| Splice isoforms : SwissVar | Q7KZN9 |
| PhosPhoSitePlus | Q7KZN9 |
| Domains : Interpro (EBI) | COX15/CtaA_fam HemeA_Synthase_type2 Peptidase_S1_PA |
| Domain families : Pfam (Sanger) | COX15-CtaA (PF02628) |
| Domain families : Pfam (NCBI) | pfam02628 |
| Conserved Domain (NCBI) | COX15 |
| DMDM Disease mutations | 1355 |
| Blocks (Seattle) | COX15 |
| Superfamily | Q7KZN9 |
| Human Protein Atlas [tissue] | ENSG00000014919-COX15 [tissue] |
| Peptide Atlas | Q7KZN9 |
| HPRD | 04707 |
| IPI | IPI00419869 IPI00455190 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q7KZN9 |
| IntAct (EBI) | Q7KZN9 |
| FunCoup | ENSG00000014919 |
| BioGRID | COX15 |
| STRING (EMBL) | COX15 |
| ZODIAC | COX15 |
| Ontologies - Pathways |
|---|
| QuickGO | Q7KZN9 |
| Ontology : AmiGO | cytochrome-c oxidase activity cytochrome-c oxidase activity cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen heme biosynthetic process heme a biosynthetic process heme a biosynthetic process heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly respiratory chain complex IV assembly integral component of membrane oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor cellular respiration oxidation-reduction process cytochrome complex proton transmembrane transport |
| Ontology : EGO-EBI | cytochrome-c oxidase activity cytochrome-c oxidase activity cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen heme biosynthetic process heme a biosynthetic process heme a biosynthetic process heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly respiratory chain complex IV assembly integral component of membrane oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor cellular respiration oxidation-reduction process cytochrome complex proton transmembrane transport |
| Pathways : KEGG | Oxidative phosphorylation Porphyrin and chlorophyll metabolism |
| NDEx Network | COX15 |
| Atlas of Cancer Signalling Network | COX15 |
| Wikipedia pathways | COX15 |
| Orthology - Evolution |
|---|
| OrthoDB | 1355 |
| GeneTree (enSembl) | ENSG00000014919 |
| Phylogenetic Trees/Animal Genes : TreeFam | COX15 |
| HOGENOM | Q7KZN9 |
| Homologs : HomoloGene | COX15 |
| Homology/Alignments : Family Browser (UCSC) | COX15 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | COX15 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | COX15 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | COX15 |
| dbVar | COX15 |
| ClinVar | COX15 |
| 1000_Genomes | COX15 |
| Exome Variant Server | COX15 |
| ExAC (Exome Aggregation Consortium) | ENSG00000014919 |
| GNOMAD Browser | ENSG00000014919 |
| Varsome Browser | COX15 |
| Genetic variants : HAPMAP | 1355 |
| Genomic Variants (DGV) | COX15 [DGVbeta] |
| DECIPHER | COX15 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | COX15 |
| Mutations |
|---|
| ICGC Data Portal | COX15 |
| TCGA Data Portal | COX15 |
| Broad Tumor Portal | COX15 |
| OASIS Portal | COX15 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | COX15 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | COX15 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search COX15 |
| DgiDB (Drug Gene Interaction Database) | COX15 |
| DoCM (Curated mutations) | COX15 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | COX15 (select a term) |
| intoGen | COX15 |
| Cancer3D | COX15(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 256000 603646 615119 |
| Orphanet | 19814 3379 |
| DisGeNET | COX15 |
| Medgen | COX15 |
| Genetic Testing Registry | COX15
|
| NextProt | Q7KZN9 [Medical] |
| TSGene | 1355 |
| GENETests | COX15 |
| Target Validation | COX15 |
| Huge Navigator |
COX15 [HugePedia] |
| snp3D : Map Gene to Disease | 1355 |
| BioCentury BCIQ | COX15 |
| ClinGen | COX15 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1355 |
| Chemical/Pharm GKB Gene | PA26779 |
| Clinical trial | COX15 |
| Miscellaneous |
|---|
| canSAR (ICR) | COX15 (select the gene name) |
| DataMed Index | COX15 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 28 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | COX15 |
| EVEX | COX15 |
| GoPubMed | COX15 |
| iHOP | COX15 |
