Identity
HGNC
LOCATION
20q11.21
LOCUSID
ALIAS
COX4,COX4-2,COX4B,COX4L2,COXIV-2,dJ857M17.2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84701
MIM: 607976
HGNC: 16232
Ensembl: ENSG00000131055
Variants:
dbSNP: 84701
ClinVar: 84701
TCGA: ENSG00000131055
COSMIC: COX4I2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131055 | ENST00000376075 | Q96KJ9 |
| ENSG00000131055 | ENST00000376075 | H6SG14 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38422899 | 2024 | HIF1A transcriptional regulation of COX4I2 impacts angiogenesis in pheochromocytoma. | 0 |
| 38422899 | 2024 | HIF1A transcriptional regulation of COX4I2 impacts angiogenesis in pheochromocytoma. | 0 |
| 36064310 | 2022 | Identification of COX4I2 as a hypoxia-associated gene acting through FGF1 to promote EMT and angiogenesis in CRC. | 5 |
| 36064310 | 2022 | Identification of COX4I2 as a hypoxia-associated gene acting through FGF1 to promote EMT and angiogenesis in CRC. | 5 |
| 33672589 | 2021 | Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency. | 5 |
| 33672589 | 2021 | Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency. | 5 |
| 31106414 | 2019 | From clinic to mechanism: Proteomics-based assessment of angiogenesis in adrenal pheochromocytoma. | 9 |
| 31106414 | 2019 | From clinic to mechanism: Proteomics-based assessment of angiogenesis in adrenal pheochromocytoma. | 9 |
| 23303788 | 2013 | Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2. | 85 |
| 23303788 | 2013 | Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2. | 85 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19268275 | 2009 | Exocrine pancreatic insufficiency, dyserythropoeitic anemia, and calvarial hyperostosis are caused by a mutation in the COX4I2 gene. | 35 |
| 19268275 | 2009 | Exocrine pancreatic insufficiency, dyserythropoeitic anemia, and calvarial hyperostosis are caused by a mutation in the COX4I2 gene. | 35 |
| 19064571 | 2008 | Polymorphisms in mitochondrial genes and prostate cancer risk. | 22 |
Citation
Dessen P
COX4I2 (cytochrome c oxidase subunit 4I2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47019/cox4i2
