Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COX5A (cytochrome c oxidase subunit 5A)

Identity

Alias_namescytochrome c oxidase subunit Va
Other aliasCOX
COX-VA
VA
HGNC (Hugo) COX5A
LocusID (NCBI) 9377
Atlas_Id 51580
Location 15q24.2  [Link to chromosome band 15q24]
Location_base_pair Starts at 74920276 and ends at 74938154 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FKBP3 (14q21.2) / COX5A (15q24.2)GSK3B (3q13.33) / COX5A (15q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COX5A   2267
Cards
Entrez_Gene (NCBI)COX5A  9377  cytochrome c oxidase subunit 5A
AliasesCOX; COX-VA; VA
GeneCards (Weizmann)COX5A
Ensembl hg19 (Hinxton)ENSG00000178741 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178741 [Gene_View]  chr15:74920276-74938154 [Contig_View]  COX5A [Vega]
ICGC DataPortalENSG00000178741
TCGA cBioPortalCOX5A
AceView (NCBI)COX5A
Genatlas (Paris)COX5A
WikiGenes9377
SOURCE (Princeton)COX5A
Genetics Home Reference (NIH)COX5A
Genomic and cartography
GoldenPath hg38 (UCSC)COX5A  -     chr15:74920276-74938154 -  15q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COX5A  -     15q24.2   [Description]    (hg19-Feb_2009)
EnsemblCOX5A - 15q24.2 [CytoView hg19]  COX5A - 15q24.2 [CytoView hg38]
Mapping of homologs : NCBICOX5A [Mapview hg19]  COX5A [Mapview hg38]
OMIM603773   
Gene and transcription
Genbank (Entrez)AI815421 AK026615 AK026623 BC024240 CR407649
RefSeq transcript (Entrez)NM_004255
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COX5A
Cluster EST : UnigeneHs.401903 [ NCBI ]
CGAP (NCI)Hs.401903
Alternative Splicing GalleryENSG00000178741
Gene ExpressionCOX5A [ NCBI-GEO ]   COX5A [ EBI - ARRAY_EXPRESS ]   COX5A [ SEEK ]   COX5A [ MEM ]
Gene Expression Viewer (FireBrowse)COX5A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9377
GTEX Portal (Tissue expression)COX5A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20674   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20674  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20674
Splice isoforms : SwissVarP20674
PhosPhoSitePlusP20674
Domains : Interpro (EBI)Cyt_c_oxidase_su5A/6   
Domain families : Pfam (Sanger)COX5A (PF02284)   
Domain families : Pfam (NCBI)pfam02284   
Conserved Domain (NCBI)COX5A
DMDM Disease mutations9377
Blocks (Seattle)COX5A
SuperfamilyP20674
Human Protein AtlasENSG00000178741
Peptide AtlasP20674
HPRD04799
IPIIPI00025086   
Protein Interaction databases
DIP (DOE-UCLA)P20674
IntAct (EBI)P20674
FunCoupENSG00000178741
BioGRIDCOX5A
STRING (EMBL)COX5A
ZODIACCOX5A
Ontologies - Pathways
QuickGOP20674
Ontology : AmiGOcytochrome-c oxidase activity  protein binding  mitochondrial inner membrane  mitochondrial inner membrane  mitochondrial respiratory chain complex IV  mitochondrial respiratory chain complex IV  mitochondrial electron transport, cytochrome c to oxygen  mitochondrial electron transport, cytochrome c to oxygen  electron carrier activity  myelin sheath  metal ion binding  extracellular exosome  hydrogen ion transmembrane transport  
Ontology : EGO-EBIcytochrome-c oxidase activity  protein binding  mitochondrial inner membrane  mitochondrial inner membrane  mitochondrial respiratory chain complex IV  mitochondrial respiratory chain complex IV  mitochondrial electron transport, cytochrome c to oxygen  mitochondrial electron transport, cytochrome c to oxygen  electron carrier activity  myelin sheath  metal ion binding  extracellular exosome  hydrogen ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Cardiac muscle contraction    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkCOX5A
Atlas of Cancer Signalling NetworkCOX5A
Wikipedia pathwaysCOX5A
Orthology - Evolution
OrthoDB9377
GeneTree (enSembl)ENSG00000178741
Phylogenetic Trees/Animal Genes : TreeFamCOX5A
HOVERGENP20674
HOGENOMP20674
Homologs : HomoloGeneCOX5A
Homology/Alignments : Family Browser (UCSC)COX5A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOX5A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COX5A
dbVarCOX5A
ClinVarCOX5A
1000_GenomesCOX5A 
Exome Variant ServerCOX5A
ExAC (Exome Aggregation Consortium)COX5A (select the gene name)
Genetic variants : HAPMAP9377
Genomic Variants (DGV)COX5A [DGVbeta]
DECIPHERCOX5A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOX5A 
Mutations
ICGC Data PortalCOX5A 
TCGA Data PortalCOX5A 
Broad Tumor PortalCOX5A
OASIS PortalCOX5A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOX5A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOX5A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COX5A
DgiDB (Drug Gene Interaction Database)COX5A
DoCM (Curated mutations)COX5A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COX5A (select a term)
intoGenCOX5A
Cancer3DCOX5A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603773   
Orphanet
MedgenCOX5A
Genetic Testing Registry COX5A
NextProtP20674 [Medical]
TSGene9377
GENETestsCOX5A
Target ValidationCOX5A
Huge Navigator COX5A [HugePedia]
snp3D : Map Gene to Disease9377
BioCentury BCIQCOX5A
ClinGenCOX5A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9377
Chemical/Pharm GKB GenePA26784
Clinical trialCOX5A
Miscellaneous
canSAR (ICR)COX5A (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOX5A
EVEXCOX5A
GoPubMedCOX5A
iHOPCOX5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:58:27 CEST 2017

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