Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

COX5B (cytochrome c oxidase subunit 5B)

Identity

Alias_namescytochrome c oxidase subunit Vb
Other aliasCOXVB
HGNC (Hugo) COX5B
LocusID (NCBI) 1329
Atlas_Id 47189
Location 2q11.2  [Link to chromosome band 2q11]
Location_base_pair Starts at 98262521 and ends at 98264657 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPYD (1p21.3) / COX5B (2q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COX5B   2269
Cards
Entrez_Gene (NCBI)COX5B  1329  cytochrome c oxidase subunit 5B
AliasesCOXVB
GeneCards (Weizmann)COX5B
Ensembl hg19 (Hinxton)ENSG00000135940 [Gene_View]  chr2:98262521-98264657 [Contig_View]  COX5B [Vega]
Ensembl hg38 (Hinxton)ENSG00000135940 [Gene_View]  chr2:98262521-98264657 [Contig_View]  COX5B [Vega]
ICGC DataPortalENSG00000135940
TCGA cBioPortalCOX5B
AceView (NCBI)COX5B
Genatlas (Paris)COX5B
WikiGenes1329
SOURCE (Princeton)COX5B
Genetics Home Reference (NIH)COX5B
Genomic and cartography
GoldenPath hg19 (UCSC)COX5B  -     chr2:98262521-98264657 +  2q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)COX5B  -     2q11.2   [Description]    (hg38-Dec_2013)
EnsemblCOX5B - 2q11.2 [CytoView hg19]  COX5B - 2q11.2 [CytoView hg38]
Mapping of homologs : NCBICOX5B [Mapview hg19]  COX5B [Mapview hg38]
OMIM123866   
Gene and transcription
Genbank (Entrez)BC006229 BT006742 CR541727 CR541753 DQ577470
RefSeq transcript (Entrez)NM_001862
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929303
Consensus coding sequences : CCDS (NCBI)COX5B
Cluster EST : UnigeneHs.1342 [ NCBI ]
CGAP (NCI)Hs.1342
Alternative Splicing GalleryENSG00000135940
Gene ExpressionCOX5B [ NCBI-GEO ]   COX5B [ EBI - ARRAY_EXPRESS ]   COX5B [ SEEK ]   COX5B [ MEM ]
Gene Expression Viewer (FireBrowse)COX5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1329
GTEX Portal (Tissue expression)COX5B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10606   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10606  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10606
Splice isoforms : SwissVarP10606
PhosPhoSitePlusP10606
Domaine pattern : Prosite (Expaxy)COX5B_1 (PS00848)    COX5B_2 (PS51359)   
Domains : Interpro (EBI)Cyt_c_oxidase_su5b    Cyt_c_oxidase_su5b_Zn_BS   
Domain families : Pfam (Sanger)COX5B (PF01215)   
Domain families : Pfam (NCBI)pfam01215   
Domain structure : Prodom (Prabi Lyon)Cyt_c_oxidase_su5b (PD007270)   
Conserved Domain (NCBI)COX5B
DMDM Disease mutations1329
Blocks (Seattle)COX5B
SuperfamilyP10606
Human Protein AtlasENSG00000135940
Peptide AtlasP10606
HPRD00467
IPIIPI00021785   
Protein Interaction databases
DIP (DOE-UCLA)P10606
IntAct (EBI)P10606
FunCoupENSG00000135940
BioGRIDCOX5B
STRING (EMBL)COX5B
ZODIACCOX5B
Ontologies - Pathways
QuickGOP10606
Ontology : AmiGOcytochrome-c oxidase activity  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, cytochrome c to oxygen  respiratory gaseous exchange  metal ion binding  extracellular exosome  hydrogen ion transmembrane transport  hydrogen ion transmembrane transport  
Ontology : EGO-EBIcytochrome-c oxidase activity  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, cytochrome c to oxygen  respiratory gaseous exchange  metal ion binding  extracellular exosome  hydrogen ion transmembrane transport  hydrogen ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Cardiac muscle contraction    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkCOX5B
Atlas of Cancer Signalling NetworkCOX5B
Wikipedia pathwaysCOX5B
Orthology - Evolution
OrthoDB1329
GeneTree (enSembl)ENSG00000135940
Phylogenetic Trees/Animal Genes : TreeFamCOX5B
HOVERGENP10606
HOGENOMP10606
Homologs : HomoloGeneCOX5B
Homology/Alignments : Family Browser (UCSC)COX5B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOX5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COX5B
dbVarCOX5B
ClinVarCOX5B
1000_GenomesCOX5B 
Exome Variant ServerCOX5B
ExAC (Exome Aggregation Consortium)COX5B (select the gene name)
Genetic variants : HAPMAP1329
Genomic Variants (DGV)COX5B [DGVbeta]
DECIPHER (Syndromes)2:98262521-98264657  ENSG00000135940
CONAN: Copy Number AnalysisCOX5B 
Mutations
ICGC Data PortalCOX5B 
TCGA Data PortalCOX5B 
Broad Tumor PortalCOX5B
OASIS PortalCOX5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOX5B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOX5B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COX5B
DgiDB (Drug Gene Interaction Database)COX5B
DoCM (Curated mutations)COX5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COX5B (select a term)
intoGenCOX5B
Cancer3DCOX5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123866   
Orphanet
MedgenCOX5B
Genetic Testing Registry COX5B
NextProtP10606 [Medical]
TSGene1329
GENETestsCOX5B
Huge Navigator COX5B [HugePedia]
snp3D : Map Gene to Disease1329
BioCentury BCIQCOX5B
ClinGenCOX5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1329
Chemical/Pharm GKB GenePA26786
Clinical trialCOX5B
Miscellaneous
canSAR (ICR)COX5B (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOX5B
EVEXCOX5B
GoPubMedCOX5B
iHOPCOX5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:01:27 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.