Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COX7B (cytochrome c oxidase subunit 7B)

Identity

Alias_namescytochrome c oxidase subunit VIIb
Other aliasAPLCC
LSDMCA2
HGNC (Hugo) COX7B
LocusID (NCBI) 1349
Atlas_Id 46806
Location Xq21.1  [Link to chromosome band Xq21]
Location_base_pair Starts at 77899464 and ends at 77905384 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COX7B (Xq21.1) / COX7B (Xq21.1)COX7B (Xq21.1) / H2AFY (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)COX7B   2291
Cards
Entrez_Gene (NCBI)COX7B  1349  cytochrome c oxidase subunit 7B
AliasesAPLCC; LSDMCA2
GeneCards (Weizmann)COX7B
Ensembl hg19 (Hinxton)ENSG00000131174 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131174 [Gene_View]  chrX:77899464-77905384 [Contig_View]  COX7B [Vega]
ICGC DataPortalENSG00000131174
TCGA cBioPortalCOX7B
AceView (NCBI)COX7B
Genatlas (Paris)COX7B
WikiGenes1349
SOURCE (Princeton)COX7B
Genetics Home Reference (NIH)COX7B
Genomic and cartography
GoldenPath hg38 (UCSC)COX7B  -     chrX:77899464-77905384 +  Xq21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)COX7B  -     Xq21.1   [Description]    (hg19-Feb_2009)
EnsemblCOX7B - Xq21.1 [CytoView hg19]  COX7B - Xq21.1 [CytoView hg38]
Mapping of homologs : NCBICOX7B [Mapview hg19]  COX7B [Mapview hg38]
OMIM300885   300887   
Gene and transcription
Genbank (Entrez)AK311879 BC018386 BT009767 CR450332 CR542124
RefSeq transcript (Entrez)NM_001866
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)COX7B
Cluster EST : UnigeneHs.522699 [ NCBI ]
CGAP (NCI)Hs.522699
Alternative Splicing GalleryENSG00000131174
Gene ExpressionCOX7B [ NCBI-GEO ]   COX7B [ EBI - ARRAY_EXPRESS ]   COX7B [ SEEK ]   COX7B [ MEM ]
Gene Expression Viewer (FireBrowse)COX7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1349
GTEX Portal (Tissue expression)COX7B
Human Protein AtlasENSG00000131174-COX7B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24311   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24311  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24311
Splice isoforms : SwissVarP24311
PhosPhoSitePlusP24311
Domains : Interpro (EBI)Cyt_c_oxidase_suVIIB    Cyt_c_oxidase_suVIIB_dom   
Domain families : Pfam (Sanger)COX7B (PF05392)   
Domain families : Pfam (NCBI)pfam05392   
Conserved Domain (NCBI)COX7B
DMDM Disease mutations1349
Blocks (Seattle)COX7B
SuperfamilyP24311
Human Protein Atlas [tissue]ENSG00000131174-COX7B [tissue]
Peptide AtlasP24311
HPRD04812
IPIIPI00028003   
Protein Interaction databases
DIP (DOE-UCLA)P24311
IntAct (EBI)P24311
FunCoupENSG00000131174
BioGRIDCOX7B
STRING (EMBL)COX7B
ZODIACCOX7B
Ontologies - Pathways
QuickGOP24311
Ontology : AmiGOcytochrome-c oxidase activity  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  central nervous system development  integral component of membrane  respiratory chain complex IV  hydrogen ion transmembrane transport  
Ontology : EGO-EBIcytochrome-c oxidase activity  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain  mitochondrial electron transport, cytochrome c to oxygen  central nervous system development  integral component of membrane  respiratory chain complex IV  hydrogen ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Cardiac muscle contraction    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkCOX7B
Atlas of Cancer Signalling NetworkCOX7B
Wikipedia pathwaysCOX7B
Orthology - Evolution
OrthoDB1349
GeneTree (enSembl)ENSG00000131174
Phylogenetic Trees/Animal Genes : TreeFamCOX7B
HOVERGENP24311
HOGENOMP24311
Homologs : HomoloGeneCOX7B
Homology/Alignments : Family Browser (UCSC)COX7B
Gene fusions - Rearrangements
Tumor Fusion PortalCOX7B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCOX7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)COX7B
dbVarCOX7B
ClinVarCOX7B
1000_GenomesCOX7B 
Exome Variant ServerCOX7B
ExAC (Exome Aggregation Consortium)ENSG00000131174
GNOMAD BrowserENSG00000131174
Genetic variants : HAPMAP1349
Genomic Variants (DGV)COX7B [DGVbeta]
DECIPHERCOX7B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCOX7B 
Mutations
ICGC Data PortalCOX7B 
TCGA Data PortalCOX7B 
Broad Tumor PortalCOX7B
OASIS PortalCOX7B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCOX7B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCOX7B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch COX7B
DgiDB (Drug Gene Interaction Database)COX7B
DoCM (Curated mutations)COX7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)COX7B (select a term)
intoGenCOX7B
Cancer3DCOX7B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300885    300887   
Orphanet2359   
DisGeNETCOX7B
MedgenCOX7B
Genetic Testing Registry COX7B
NextProtP24311 [Medical]
TSGene1349
GENETestsCOX7B
Target ValidationCOX7B
Huge Navigator COX7B [HugePedia]
snp3D : Map Gene to Disease1349
BioCentury BCIQCOX7B
ClinGenCOX7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1349
Chemical/Pharm GKB GenePA26809
Clinical trialCOX7B
Miscellaneous
canSAR (ICR)COX7B (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCOX7B
EVEXCOX7B
GoPubMedCOX7B
iHOPCOX7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:08:45 CET 2017

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