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CP (ceruloplasmin (ferroxidase))

Identity

Other namesCP-2
HGNC (Hugo) CP
LocusID (NCBI) 1356
Atlas_Id 45927
Location 3q24  [Link to chromosome band 3q24]
Location_base_pair Starts at 148890290 and ends at 148939832 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATXN7 (3p14.1) / CP (3q24)CP (3q24) / SOX5 (12p12.1)CP (3q24) / WWTR1 (3q25.1)
CP 3q24 / SOX5 12p12.1CP 3q24 / WWTR1 3q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 0 ]
  Lung: Translocations in Adenocarcinoma

External links

Nomenclature
HGNC (Hugo)CP   2295
Cards
Entrez_Gene (NCBI)CP  1356  ceruloplasmin (ferroxidase)
AliasesCP-2
GeneCards (Weizmann)CP
Ensembl hg19 (Hinxton)ENSG00000047457 [Gene_View]  chr3:148890290-148939832 [Contig_View]  CP [Vega]
Ensembl hg38 (Hinxton)ENSG00000047457 [Gene_View]  chr3:148890290-148939832 [Contig_View]  CP [Vega]
ICGC DataPortalENSG00000047457
TCGA cBioPortalCP
AceView (NCBI)CP
Genatlas (Paris)CP
WikiGenes1356
SOURCE (Princeton)CP
Genomic and cartography
GoldenPath hg19 (UCSC)CP  -     chr3:148890290-148939832 -  3q24   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CP  -     3q24   [Description]    (hg38-Dec_2013)
EnsemblCP - 3q24 [CytoView hg19]  CP - 3q24 [CytoView hg38]
Mapping of homologs : NCBICP [Mapview hg19]  CP [Mapview hg38]
OMIM117700   604290   
Gene and transcription
Genbank (Entrez)AK095290 AK291219 AK299272 AK309279 BC039239
RefSeq transcript (Entrez)NM_000096
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_011800 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)CP
Cluster EST : UnigeneHs.558314 [ NCBI ]
CGAP (NCI)Hs.558314
Alternative Splicing GalleryENSG00000047457
Gene ExpressionCP [ NCBI-GEO ]   CP [ EBI - ARRAY_EXPRESS ]   CP [ SEEK ]   CP [ MEM ]
Gene Expression Viewer (FireBrowse)CP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1356
GTEX Portal (Tissue expression)CP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00450 (Uniprot)
NextProtP00450  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00450
Splice isoforms : SwissVarP00450 (Swissvar)
Catalytic activity : Enzyme1.16.3.1 [ Enzyme-Expasy ]   1.16.3.11.16.3.1 [ IntEnz-EBI ]   1.16.3.1 [ BRENDA ]   1.16.3.1 [ KEGG ]   
PhosPhoSitePlusP00450
Domaine pattern : Prosite (Expaxy)MULTICOPPER_OXIDASE1 (PS00079)    MULTICOPPER_OXIDASE2 (PS00080)   
Domains : Interpro (EBI)CP    Cu-oxidase    Cu-oxidase_2    Cu-oxidase_3    Cu_oxidase_CS    Cu_oxidase_Cu_BS    Cupredoxin   
Domain families : Pfam (Sanger)Cu-oxidase (PF00394)    Cu-oxidase_2 (PF07731)    Cu-oxidase_3 (PF07732)   
Domain families : Pfam (NCBI)pfam00394    pfam07731    pfam07732   
DMDM Disease mutations1356
Blocks (Seattle)CP
PDB (SRS)1KCW    2J5W    4EJX    4ENZ   
PDB (PDBSum)1KCW    2J5W    4EJX    4ENZ   
PDB (IMB)1KCW    2J5W    4EJX    4ENZ   
PDB (RSDB)1KCW    2J5W    4EJX    4ENZ   
Structural Biology KnowledgeBase1KCW    2J5W    4EJX    4ENZ   
SCOP (Structural Classification of Proteins)1KCW    2J5W    4EJX    4ENZ   
CATH (Classification of proteins structures)1KCW    2J5W    4EJX    4ENZ   
SuperfamilyP00450
Human Protein AtlasENSG00000047457
Peptide AtlasP00450
HPRD00317
IPIIPI00017601   IPI00946590   IPI00947307   IPI00793108   IPI00879084   
Protein Interaction databases
DIP (DOE-UCLA)P00450
IntAct (EBI)P00450
FunCoupENSG00000047457
BioGRIDCP
STRING (EMBL)CP
ZODIACCP
Ontologies - Pathways
QuickGOP00450
Ontology : AmiGOliver development  ferroxidase activity  copper ion binding  extracellular region  extracellular region  extracellular space  lysosomal membrane  copper ion transport  cellular iron ion homeostasis  aging  response to nutrient  lung development  anchored component of plasma membrane  response to copper ion  chaperone binding  oxidation-reduction process  extracellular exosome  blood microparticle  
Ontology : EGO-EBIliver development  ferroxidase activity  copper ion binding  extracellular region  extracellular region  extracellular space  lysosomal membrane  copper ion transport  cellular iron ion homeostasis  aging  response to nutrient  lung development  anchored component of plasma membrane  response to copper ion  chaperone binding  oxidation-reduction process  extracellular exosome  blood microparticle  
Pathways : KEGGPorphyrin and chlorophyll metabolism   
NDEx Network
Atlas of Cancer Signalling NetworkCP
Wikipedia pathwaysCP
Orthology - Evolution
OrthoDB1356
GeneTree (enSembl)ENSG00000047457
Phylogenetic Trees/Animal Genes : TreeFamCP
Homologs : HomoloGeneCP
Homology/Alignments : Family Browser (UCSC)CP
Gene fusions - Rearrangements
Fusion: TCGACP 3q24 SOX5 12p12.1 BRCA
Fusion: TCGACP 3q24 WWTR1 3q25.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerCP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CP
dbVarCP
ClinVarCP
1000_GenomesCP 
Exome Variant ServerCP
ExAC (Exome Aggregation Consortium)CP (select the gene name)
Genetic variants : HAPMAP1356
Genomic Variants (DGV)CP [DGVbeta]
Mutations
ICGC Data PortalCP 
TCGA Data PortalCP 
Broad Tumor PortalCP
OASIS PortalCP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CP
DgiDB (Drug Gene Interaction Database)CP
DoCM (Curated mutations)CP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CP (select a term)
intoGenCP
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:148890290-148939832  ENSG00000047457
CONAN: Copy Number AnalysisCP 
Mutations and Diseases : HGMDCP
OMIM117700    604290   
MedgenCP
Genetic Testing Registry CP
NextProtP00450 [Medical]
TSGene1356
GENETestsCP
Huge Navigator CP [HugePedia]
snp3D : Map Gene to Disease1356
BioCentury BCIQCP
ClinGenCP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1356
Chemical/Pharm GKB GenePA26815
Clinical trialCP
Miscellaneous
canSAR (ICR)CP (select the gene name)
Probes
Litterature
PubMed165 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCP
EVEXCP
GoPubMedCP
iHOPCP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:01:07 CEST 2016

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