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CP (ceruloplasmin)

Identity

Alias (NCBI)CP-2
HGNC (Hugo) CP
HGNC Alias nameferroxidase
HGNC Previous nameceruloplasmin (ferroxidase)
LocusID (NCBI) 1356
Atlas_Id 45927
Location 3q24  [Link to chromosome band 3q24]
Location_base_pair Starts at 149172497 and ends at 149221829 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATXN7 (3p14.1) / CP (3q24)CP (3q24) / SOX5 (12p12.1)CP (3q24) / WWTR1 (3q25.1)
CP 3q24 / SOX5 12p12.1CP 3q24 / WWTR1 3q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CP   2295
Cards
Entrez_Gene (NCBI)CP    ceruloplasmin
AliasesCP-2
GeneCards (Weizmann)CP
Ensembl hg19 (Hinxton)ENSG00000047457 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000047457 [Gene_View]  ENSG00000047457 [Sequence]  chr3:149172497-149221829 [Contig_View]  CP [Vega]
ICGC DataPortalENSG00000047457
TCGA cBioPortalCP
AceView (NCBI)CP
Genatlas (Paris)CP
SOURCE (Princeton)CP
Genetics Home Reference (NIH)CP
Genomic and cartography
GoldenPath hg38 (UCSC)CP  -     chr3:149172497-149221829 -  3q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CP  -     3q24   [Description]    (hg19-Feb_2009)
GoldenPathCP - 3q24 [CytoView hg19]  CP - 3q24 [CytoView hg38]
ImmunoBaseENSG00000047457
Genome Data Viewer NCBICP [Mapview hg19]  
OMIM117700   604290   
Gene and transcription
Genbank (Entrez)AK095290 AK291219 AK299272 AK309279 BC039239
RefSeq transcript (Entrez)NM_000096
Consensus coding sequences : CCDS (NCBI)CP
Gene ExpressionCP [ NCBI-GEO ]   CP [ EBI - ARRAY_EXPRESS ]   CP [ SEEK ]   CP [ MEM ]
Gene Expression Viewer (FireBrowse)CP [ Firebrowse - Broad ]
GenevisibleExpression of CP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1356
GTEX Portal (Tissue expression)CP
Human Protein AtlasENSG00000047457-CP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00450   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP00450  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00450
Catalytic activity : Enzyme1.16.3.1 [ Enzyme-Expasy ]   1.16.3.11.16.3.1 [ IntEnz-EBI ]   1.16.3.1 [ BRENDA ]   1.16.3.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP00450
Domaine pattern : Prosite (Expaxy)MULTICOPPER_OXIDASE1 (PS00079)    MULTICOPPER_OXIDASE2 (PS00080)   
Domains : Interpro (EBI)Cu-oxidase    Cu-oxidase_2    Cu-oxidase_3    Cu_oxidase_CS    Cu_oxidase_Cu_BS    Cupredoxin   
Domain families : Pfam (Sanger)Cu-oxidase (PF00394)    Cu-oxidase_2 (PF07731)    Cu-oxidase_3 (PF07732)   
Domain families : Pfam (NCBI)pfam00394    pfam07731    pfam07732   
Conserved Domain (NCBI)CP
PDB (RSDB)1KCW    2J5W    4EJX    4ENZ   
PDB Europe1KCW    2J5W    4EJX    4ENZ   
PDB (PDBSum)1KCW    2J5W    4EJX    4ENZ   
PDB (IMB)1KCW    2J5W    4EJX    4ENZ   
Structural Biology KnowledgeBase1KCW    2J5W    4EJX    4ENZ   
SCOP (Structural Classification of Proteins)1KCW    2J5W    4EJX    4ENZ   
CATH (Classification of proteins structures)1KCW    2J5W    4EJX    4ENZ   
SuperfamilyP00450
AlphaFold pdb e-kbP00450   
Human Protein Atlas [tissue]ENSG00000047457-CP [tissue]
HPRD00317
Protein Interaction databases
DIP (DOE-UCLA)P00450
IntAct (EBI)P00450
BioGRIDCP
STRING (EMBL)CP
ZODIACCP
Ontologies - Pathways
QuickGOP00450
Ontology : AmiGOferroxidase activity  copper ion binding  extracellular region  extracellular region  extracellular space  extracellular space  lysosomal membrane  endoplasmic reticulum lumen  plasma membrane  copper ion transport  iron ion transport  cellular iron ion homeostasis  oxidoreductase activity  post-translational protein modification  cellular protein metabolic process  chaperone binding  iron ion homeostasis  extracellular exosome  blood microparticle  
Ontology : EGO-EBIferroxidase activity  copper ion binding  extracellular region  extracellular region  extracellular space  extracellular space  lysosomal membrane  endoplasmic reticulum lumen  plasma membrane  copper ion transport  iron ion transport  cellular iron ion homeostasis  oxidoreductase activity  post-translational protein modification  cellular protein metabolic process  chaperone binding  iron ion homeostasis  extracellular exosome  blood microparticle  
Pathways : KEGGPorphyrin and chlorophyll metabolism   
NDEx NetworkCP
Atlas of Cancer Signalling NetworkCP
Wikipedia pathwaysCP
Orthology - Evolution
OrthoDB1356
GeneTree (enSembl)ENSG00000047457
Phylogenetic Trees/Animal Genes : TreeFamCP
Homologs : HomoloGeneCP
Homology/Alignments : Family Browser (UCSC)CP
Gene fusions - Rearrangements
Fusion : MitelmanCP/SOX5 [3q24/12p12.1]  
Fusion : MitelmanCP/WWTR1 [3q24/3q25.1]  
Fusion : QuiverCP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CP
dbVarCP
ClinVarCP
MonarchCP
1000_GenomesCP 
Exome Variant ServerCP
GNOMAD BrowserENSG00000047457
Varsome BrowserCP
ACMGCP variants
VarityP00450
Genomic Variants (DGV)CP [DGVbeta]
DECIPHERCP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCP 
Mutations
ICGC Data PortalCP 
TCGA Data PortalCP 
Broad Tumor PortalCP
OASIS PortalCP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCP
Mutations and Diseases : HGMDCP
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCP
DgiDB (Drug Gene Interaction Database)CP
DoCM (Curated mutations)CP
CIViC (Clinical Interpretations of Variants in Cancer)CP
Cancer3DCP
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM117700    604290   
Orphanet10633   
DisGeNETCP
MedgenCP
Genetic Testing Registry CP
NextProtP00450 [Medical]
GENETestsCP
Target ValidationCP
Huge Navigator CP [HugePedia]
ClinGenCP
Clinical trials, drugs, therapy
MyCancerGenomeCP
Protein Interactions : CTDCP
Pharm GKB GenePA26815
PharosP00450
Clinical trialCP
Miscellaneous
canSAR (ICR)CP
HarmonizomeCP
DataMed IndexCP
Probes
Litterature
PubMed202 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:04:58 CEST 2021

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