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CPA1 (carboxypeptidase A1)

Identity

Alias_namesCPA
carboxypeptidase A1 (pancreatic)
Other alias
HGNC (Hugo) CPA1
LocusID (NCBI) 1357
Atlas_Id 56385
Location 7q32.2  [Link to chromosome band 7q32]
Location_base_pair Starts at 130020212 and ends at 130027949 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CPA1 (7q32.2) / CPA1 (7q32.2)GCG (2q24.2) / CPA1 (7q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPA1   2296
Cards
Entrez_Gene (NCBI)CPA1  1357  carboxypeptidase A1
AliasesCPA
GeneCards (Weizmann)CPA1
Ensembl hg19 (Hinxton)ENSG00000091704 [Gene_View]  chr7:130020212-130027949 [Contig_View]  CPA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000091704 [Gene_View]  chr7:130020212-130027949 [Contig_View]  CPA1 [Vega]
ICGC DataPortalENSG00000091704
TCGA cBioPortalCPA1
AceView (NCBI)CPA1
Genatlas (Paris)CPA1
WikiGenes1357
SOURCE (Princeton)CPA1
Genetics Home Reference (NIH)CPA1
Genomic and cartography
GoldenPath hg19 (UCSC)CPA1  -     chr7:130020212-130027949 +  7q32.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPA1  -     7q32.2   [Description]    (hg38-Dec_2013)
EnsemblCPA1 - 7q32.2 [CytoView hg19]  CPA1 - 7q32.2 [CytoView hg38]
Mapping of homologs : NCBICPA1 [Mapview hg19]  CPA1 [Mapview hg38]
OMIM114850   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001868
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CPA1
Cluster EST : UnigeneHs.2879 [ NCBI ]
CGAP (NCI)Hs.2879
Alternative Splicing GalleryENSG00000091704
Gene ExpressionCPA1 [ NCBI-GEO ]   CPA1 [ EBI - ARRAY_EXPRESS ]   CPA1 [ SEEK ]   CPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)CPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1357
GTEX Portal (Tissue expression)CPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15085   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15085  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15085
Splice isoforms : SwissVarP15085
Catalytic activity : Enzyme3.4.17.1 [ Enzyme-Expasy ]   3.4.17.13.4.17.1 [ IntEnz-EBI ]   3.4.17.1 [ BRENDA ]   3.4.17.1 [ KEGG ]   
PhosPhoSitePlusP15085
Domaine pattern : Prosite (Expaxy)CARBOXYPEPT_ZN_1 (PS00132)    CARBOXYPEPT_ZN_2 (PS00133)   
Domains : Interpro (EBI)M14A_act_pep    Peptidase_M14    Propept_inh   
Domain families : Pfam (Sanger)Peptidase_M14 (PF00246)    Propep_M14 (PF02244)   
Domain families : Pfam (NCBI)pfam00246    pfam02244   
Domain families : Smart (EMBL)Zn_pept (SM00631)  
Conserved Domain (NCBI)CPA1
DMDM Disease mutations1357
Blocks (Seattle)CPA1
PDB (SRS)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
PDB (PDBSum)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
PDB (IMB)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
PDB (RSDB)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
Structural Biology KnowledgeBase2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
SCOP (Structural Classification of Proteins)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
CATH (Classification of proteins structures)2V77    3FJU    4UEE    4UEF    4UEZ    4UF4   
SuperfamilyP15085
Human Protein AtlasENSG00000091704
Peptide AtlasP15085
HPRD00269
IPIIPI00009823   IPI00908952   IPI00946823   IPI00946308   
Protein Interaction databases
DIP (DOE-UCLA)P15085
IntAct (EBI)P15085
FunCoupENSG00000091704
BioGRIDCPA1
STRING (EMBL)CPA1
ZODIACCPA1
Ontologies - Pathways
QuickGOP15085
Ontology : AmiGOmetallocarboxypeptidase activity  extracellular space  proteolysis  zinc ion binding  
Ontology : EGO-EBImetallocarboxypeptidase activity  extracellular space  proteolysis  zinc ion binding  
Pathways : KEGGPancreatic secretion    Protein digestion and absorption   
NDEx NetworkCPA1
Atlas of Cancer Signalling NetworkCPA1
Wikipedia pathwaysCPA1
Orthology - Evolution
OrthoDB1357
GeneTree (enSembl)ENSG00000091704
Phylogenetic Trees/Animal Genes : TreeFamCPA1
HOVERGENP15085
HOGENOMP15085
Homologs : HomoloGeneCPA1
Homology/Alignments : Family Browser (UCSC)CPA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPA1
dbVarCPA1
ClinVarCPA1
1000_GenomesCPA1 
Exome Variant ServerCPA1
ExAC (Exome Aggregation Consortium)CPA1 (select the gene name)
Genetic variants : HAPMAP1357
Genomic Variants (DGV)CPA1 [DGVbeta]
DECIPHER (Syndromes)7:130020212-130027949  ENSG00000091704
CONAN: Copy Number AnalysisCPA1 
Mutations
ICGC Data PortalCPA1 
TCGA Data PortalCPA1 
Broad Tumor PortalCPA1
OASIS PortalCPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPA1
DgiDB (Drug Gene Interaction Database)CPA1
DoCM (Curated mutations)CPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPA1 (select a term)
intoGenCPA1
Cancer3DCPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114850   
Orphanet937   
MedgenCPA1
Genetic Testing Registry CPA1
NextProtP15085 [Medical]
TSGene1357
GENETestsCPA1
Huge Navigator CPA1 [HugePedia]
snp3D : Map Gene to Disease1357
BioCentury BCIQCPA1
ClinGenCPA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1357
Chemical/Pharm GKB GenePA26816
Clinical trialCPA1
Miscellaneous
canSAR (ICR)CPA1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPA1
EVEXCPA1
GoPubMedCPA1
iHOPCPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:01:30 CET 2017

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