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CPA3 (carboxypeptidase A3 (mast cell))

Identity

Alias_namescarboxypeptidase A3 (mast cell)
Other aliasMC-CPA
HGNC (Hugo) CPA3
LocusID (NCBI) 1359
Atlas_Id 62045
Location 3q24  [Link to chromosome band 3q24]
Location_base_pair Starts at 148583043 and ends at 148614872 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TFRC (3q29) / CPA3 (3q24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPA3   2298
Cards
Entrez_Gene (NCBI)CPA3  1359  carboxypeptidase A3 (mast cell)
AliasesMC-CPA
GeneCards (Weizmann)CPA3
Ensembl hg19 (Hinxton)ENSG00000163751 [Gene_View]  chr3:148583043-148614872 [Contig_View]  CPA3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163751 [Gene_View]  chr3:148583043-148614872 [Contig_View]  CPA3 [Vega]
ICGC DataPortalENSG00000163751
TCGA cBioPortalCPA3
AceView (NCBI)CPA3
Genatlas (Paris)CPA3
WikiGenes1359
SOURCE (Princeton)CPA3
Genetics Home Reference (NIH)CPA3
Genomic and cartography
GoldenPath hg19 (UCSC)CPA3  -     chr3:148583043-148614872 +  3q24   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPA3  -     3q24   [Description]    (hg38-Dec_2013)
EnsemblCPA3 - 3q24 [CytoView hg19]  CPA3 - 3q24 [CytoView hg38]
Mapping of homologs : NCBICPA3 [Mapview hg19]  CPA3 [Mapview hg38]
OMIM114851   
Gene and transcription
Genbank (Entrez)AK313628 BC012613 BF508919 BG501260 DQ892805
RefSeq transcript (Entrez)NM_001870
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)CPA3
Cluster EST : UnigeneHs.646 [ NCBI ]
CGAP (NCI)Hs.646
Alternative Splicing GalleryENSG00000163751
Gene ExpressionCPA3 [ NCBI-GEO ]   CPA3 [ EBI - ARRAY_EXPRESS ]   CPA3 [ SEEK ]   CPA3 [ MEM ]
Gene Expression Viewer (FireBrowse)CPA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1359
GTEX Portal (Tissue expression)CPA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15088   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15088  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15088
Splice isoforms : SwissVarP15088
Catalytic activity : Enzyme3.4.17.1 [ Enzyme-Expasy ]   3.4.17.13.4.17.1 [ IntEnz-EBI ]   3.4.17.1 [ BRENDA ]   3.4.17.1 [ KEGG ]   
PhosPhoSitePlusP15088
Domaine pattern : Prosite (Expaxy)CARBOXYPEPT_ZN_2 (PS00133)   
Domains : Interpro (EBI)Peptidase_M14    Prot_inh_M14A    Prot_inh_propept   
Domain families : Pfam (Sanger)Peptidase_M14 (PF00246)    Propep_M14 (PF02244)   
Domain families : Pfam (NCBI)pfam00246    pfam02244   
Domain families : Smart (EMBL)Zn_pept (SM00631)  
Conserved Domain (NCBI)CPA3
DMDM Disease mutations1359
Blocks (Seattle)CPA3
SuperfamilyP15088
Human Protein AtlasENSG00000163751
Peptide AtlasP15088
HPRD00270
IPIIPI00009829   
Protein Interaction databases
DIP (DOE-UCLA)P15088
IntAct (EBI)P15088
FunCoupENSG00000163751
BioGRIDCPA3
STRING (EMBL)CPA3
ZODIACCPA3
Ontologies - Pathways
QuickGOP15088
Ontology : AmiGOangiotensin maturation  positive regulation of defense response to virus by host  metallocarboxypeptidase activity  metallocarboxypeptidase activity  extracellular region  proteolysis  zinc ion binding  transport vesicle  secretory granule  cellular protein metabolic process  
Ontology : EGO-EBIangiotensin maturation  positive regulation of defense response to virus by host  metallocarboxypeptidase activity  metallocarboxypeptidase activity  extracellular region  proteolysis  zinc ion binding  transport vesicle  secretory granule  cellular protein metabolic process  
Pathways : KEGGRenin-angiotensin system    Pancreatic secretion    Protein digestion and absorption   
NDEx NetworkCPA3
Atlas of Cancer Signalling NetworkCPA3
Wikipedia pathwaysCPA3
Orthology - Evolution
OrthoDB1359
GeneTree (enSembl)ENSG00000163751
Phylogenetic Trees/Animal Genes : TreeFamCPA3
HOVERGENP15088
HOGENOMP15088
Homologs : HomoloGeneCPA3
Homology/Alignments : Family Browser (UCSC)CPA3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPA3
dbVarCPA3
ClinVarCPA3
1000_GenomesCPA3 
Exome Variant ServerCPA3
ExAC (Exome Aggregation Consortium)CPA3 (select the gene name)
Genetic variants : HAPMAP1359
Genomic Variants (DGV)CPA3 [DGVbeta]
DECIPHER (Syndromes)3:148583043-148614872  ENSG00000163751
CONAN: Copy Number AnalysisCPA3 
Mutations
ICGC Data PortalCPA3 
TCGA Data PortalCPA3 
Broad Tumor PortalCPA3
OASIS PortalCPA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPA3
DgiDB (Drug Gene Interaction Database)CPA3
DoCM (Curated mutations)CPA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPA3 (select a term)
intoGenCPA3
Cancer3DCPA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114851   
Orphanet
MedgenCPA3
Genetic Testing Registry CPA3
NextProtP15088 [Medical]
TSGene1359
GENETestsCPA3
Huge Navigator CPA3 [HugePedia]
snp3D : Map Gene to Disease1359
BioCentury BCIQCPA3
ClinGenCPA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1359
Chemical/Pharm GKB GenePA26818
Clinical trialCPA3
Miscellaneous
canSAR (ICR)CPA3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPA3
EVEXCPA3
GoPubMedCPA3
iHOPCPA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:00:11 CET 2017

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