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CPA6 (carboxypeptidase A6)

Identity

Alias_symbol (synonym)CPAH
Other aliasETL5
FEB11
HGNC (Hugo) CPA6
LocusID (NCBI) 57094
Atlas_Id 43944
Location 8q13.2  [Link to chromosome band 8q13]
Location_base_pair Starts at 67422170 and ends at 67746385 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARFGEF1 (8q13.2) / CPA6 (8q13.2)KIAA1429 (8q22.1) / CPA6 (8q13.2)ARFGEF1 8q13.2 / CPA6 8q13.2
KIAA1429 8q22.1 / CPA6 8q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPA6   17245
Cards
Entrez_Gene (NCBI)CPA6  57094  carboxypeptidase A6
AliasesCPAH; ETL5; FEB11
GeneCards (Weizmann)CPA6
Ensembl hg19 (Hinxton)ENSG00000165078 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165078 [Gene_View]  chr8:67422170-67746385 [Contig_View]  CPA6 [Vega]
ICGC DataPortalENSG00000165078
TCGA cBioPortalCPA6
AceView (NCBI)CPA6
Genatlas (Paris)CPA6
WikiGenes57094
SOURCE (Princeton)CPA6
Genetics Home Reference (NIH)CPA6
Genomic and cartography
GoldenPath hg38 (UCSC)CPA6  -     chr8:67422170-67746385 -  8q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CPA6  -     8q13.2   [Description]    (hg19-Feb_2009)
EnsemblCPA6 - 8q13.2 [CytoView hg19]  CPA6 - 8q13.2 [CytoView hg38]
Mapping of homologs : NCBICPA6 [Mapview hg19]  CPA6 [Mapview hg38]
OMIM609562   614417   614418   
Gene and transcription
Genbank (Entrez)AF221594 AY044833 BC033684 BI756197 BK000188
RefSeq transcript (Entrez)NM_001127445 NM_020361
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CPA6
Cluster EST : UnigeneHs.658850 [ NCBI ]
CGAP (NCI)Hs.658850
Alternative Splicing GalleryENSG00000165078
Gene ExpressionCPA6 [ NCBI-GEO ]   CPA6 [ EBI - ARRAY_EXPRESS ]   CPA6 [ SEEK ]   CPA6 [ MEM ]
Gene Expression Viewer (FireBrowse)CPA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57094
GTEX Portal (Tissue expression)CPA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N4T0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N4T0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N4T0
Splice isoforms : SwissVarQ8N4T0
Catalytic activity : Enzyme3.4.17.- [ Enzyme-Expasy ]   3.4.17.-3.4.17.- [ IntEnz-EBI ]   3.4.17.- [ BRENDA ]   3.4.17.- [ KEGG ]   
PhosPhoSitePlusQ8N4T0
Domaine pattern : Prosite (Expaxy)CARBOXYPEPT_ZN_2 (PS00133)   
Domains : Interpro (EBI)CPAH    M14A_act_pep    Peptidase_M14    Propept_inh   
Domain families : Pfam (Sanger)Peptidase_M14 (PF00246)    Propep_M14 (PF02244)   
Domain families : Pfam (NCBI)pfam00246    pfam02244   
Domain families : Smart (EMBL)Zn_pept (SM00631)  
Conserved Domain (NCBI)CPA6
DMDM Disease mutations57094
Blocks (Seattle)CPA6
SuperfamilyQ8N4T0
Human Protein AtlasENSG00000165078
Peptide AtlasQ8N4T0
HPRD09891
IPIIPI00166764   IPI00386667   IPI00168794   IPI00945842   
Protein Interaction databases
DIP (DOE-UCLA)Q8N4T0
IntAct (EBI)Q8N4T0
FunCoupENSG00000165078
BioGRIDCPA6
STRING (EMBL)CPA6
ZODIACCPA6
Ontologies - Pathways
QuickGOQ8N4T0
Ontology : AmiGOmetallocarboxypeptidase activity  metallocarboxypeptidase activity  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  
Ontology : EGO-EBImetallocarboxypeptidase activity  metallocarboxypeptidase activity  proteinaceous extracellular matrix  extracellular space  proteolysis  zinc ion binding  
NDEx NetworkCPA6
Atlas of Cancer Signalling NetworkCPA6
Wikipedia pathwaysCPA6
Orthology - Evolution
OrthoDB57094
GeneTree (enSembl)ENSG00000165078
Phylogenetic Trees/Animal Genes : TreeFamCPA6
HOVERGENQ8N4T0
HOGENOMQ8N4T0
Homologs : HomoloGeneCPA6
Homology/Alignments : Family Browser (UCSC)CPA6
Gene fusions - Rearrangements
Fusion : MitelmanARFGEF1/CPA6 [8q13.2/8q13.2]  [t(8;8)(q13;q13)]  
Fusion : MitelmanKIAA1429/CPA6 [8q22.1/8q13.2]  [t(8;8)(q13;q22)]  
Fusion: TCGAARFGEF1 8q13.2 CPA6 8q13.2 BRCA
Fusion: TCGAKIAA1429 8q22.1 CPA6 8q13.2 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPA6
dbVarCPA6
ClinVarCPA6
1000_GenomesCPA6 
Exome Variant ServerCPA6
ExAC (Exome Aggregation Consortium)CPA6 (select the gene name)
Genetic variants : HAPMAP57094
Genomic Variants (DGV)CPA6 [DGVbeta]
DECIPHERCPA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCPA6 
Mutations
ICGC Data PortalCPA6 
TCGA Data PortalCPA6 
Broad Tumor PortalCPA6
OASIS PortalCPA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch CPA6
DgiDB (Drug Gene Interaction Database)CPA6
DoCM (Curated mutations)CPA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPA6 (select a term)
intoGenCPA6
Cancer3DCPA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609562    614417    614418   
Orphanet17579    17531   
MedgenCPA6
Genetic Testing Registry CPA6
NextProtQ8N4T0 [Medical]
TSGene57094
GENETestsCPA6
Target ValidationCPA6
Huge Navigator CPA6 [HugePedia]
snp3D : Map Gene to Disease57094
BioCentury BCIQCPA6
ClinGenCPA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57094
Chemical/Pharm GKB GenePA38444
Clinical trialCPA6
Miscellaneous
canSAR (ICR)CPA6 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPA6
EVEXCPA6
GoPubMedCPA6
iHOPCPA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:03:31 CEST 2017

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