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CPD (carboxypeptidase D)

Identity

Other namesGP180
HGNC (Hugo) CPD
LocusID (NCBI) 1362
Atlas_Id 46417
Location 17q11.2
Location_base_pair Starts at 28707496 and ends at 28796675 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CPD (17q11.2) / AATF (17q12)CPD (17q11.2) / CPD (17q11.2)CPD (17q11.2) / ERBB2 (17q12)
CPD (17q11.2) / GSTO1 (10q25.1)CPD (17q11.2) / ORMDL3 (17q12)CPD (17q11.2) / PIGW (17q12)
CPD (17q11.2) / SKAP1 (17q21.32)CPD (17q11.2) / TBX2 (17q23.2)CPD (17q11.2) / UQCRQ (5q31.1)
GOSR1 (17q11.2) / CPD (17q11.2)NUFIP2 (17q11.2) / CPD (17q11.2)RGMB (5q15) / CPD (17q11.2)
SYAP1 (Xp22.2) / CPD (17q11.2)CPD 17q11.2 / AATF 17q12CPD 17q11.2 / ORMDL3 17q12
CPD 17q11.2 / PIGW 17q12CPD 17q11.2 / SKAP1 17q21.32CPD 17q11.2 / TBX2 17q23.2
NUFIP2 17q11.2 / CPD 17q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPD   2301
Cards
Entrez_Gene (NCBI)CPD  1362  carboxypeptidase D
GeneCards (Weizmann)CPD
Ensembl hg19 (Hinxton)ENSG00000108582 [Gene_View]  chr17:28707496-28796675 [Contig_View]  CPD [Vega]
Ensembl hg38 (Hinxton)ENSG00000108582 [Gene_View]  chr17:28707496-28796675 [Contig_View]  CPD [Vega]
ICGC DataPortalENSG00000108582
TCGA cBioPortalCPD
AceView (NCBI)CPD
Genatlas (Paris)CPD
WikiGenes1362
SOURCE (Princeton)CPD
Genomic and cartography
GoldenPath hg19 (UCSC)CPD  -     chr17:28707496-28796675 +  17q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPD  -     17q11.2   [Description]    (hg38-Dec_2013)
EnsemblCPD - 17q11.2 [CytoView hg19]  CPD - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBICPD [Mapview hg19]  CPD [Mapview hg38]
OMIM603102   
Gene and transcription
Genbank (Entrez)AK302497 AK302878 AK316409 AL049339 BC020457
RefSeq transcript (Entrez)NM_001199775 NM_001304
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)CPD
Cluster EST : UnigeneHs.446079 [ NCBI ]
CGAP (NCI)Hs.446079
Alternative Splicing : Fast-db (Paris)GSHG0012363
Alternative Splicing GalleryENSG00000108582
Gene ExpressionCPD [ NCBI-GEO ]   CPD [ EBI - ARRAY_EXPRESS ]   CPD [ SEEK ]   CPD [ MEM ]
Gene Expression Viewer (FireBrowse)CPD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1362
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75976 (Uniprot)
NextProtO75976  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75976
Splice isoforms : SwissVarO75976 (Swissvar)
Catalytic activity : Enzyme3.4.17.22 [ Enzyme-Expasy ]   3.4.17.223.4.17.22 [ IntEnz-EBI ]   3.4.17.22 [ BRENDA ]   3.4.17.22 [ KEGG ]   
PhosPhoSitePlusO75976
Domaine pattern : Prosite (Expaxy)CARBOXYPEPT_ZN_1 (PS00132)    CARBOXYPEPT_ZN_2 (PS00133)   
Domains : Interpro (EBI)CarboxyPept-like_regulatory    CarboxyPept_regulatory_dom    Pept_M14B_carboxypept_D2    Peptidase_M14   
Domain families : Pfam (Sanger)Peptidase_M14 (PF00246)   
Domain families : Pfam (NCBI)pfam00246   
Domain families : Smart (EMBL)Zn_pept (SM00631)  
DMDM Disease mutations1362
Blocks (Seattle)CPD
SuperfamilyO75976
Human Protein AtlasENSG00000108582
Peptide AtlasO75976
HPRD04375
IPIIPI00027078   IPI00921861   IPI00979354   
Protein Interaction databases
DIP (DOE-UCLA)O75976
IntAct (EBI)O75976
FunCoupENSG00000108582
BioGRIDCPD
STRING (EMBL)CPD
ZODIACCPD
Ontologies - Pathways
QuickGOO75976
Ontology : AmiGOmetallocarboxypeptidase activity  serine-type carboxypeptidase activity  extracellular space  nucleus  trans-Golgi network  plasma membrane  peptide metabolic process  zinc ion binding  membrane  integral component of membrane  protein processing  extracellular exosome  
Ontology : EGO-EBImetallocarboxypeptidase activity  serine-type carboxypeptidase activity  extracellular space  nucleus  trans-Golgi network  plasma membrane  peptide metabolic process  zinc ion binding  membrane  integral component of membrane  protein processing  extracellular exosome  
NDEx Network
Atlas of Cancer Signalling NetworkCPD
Wikipedia pathwaysCPD
Orthology - Evolution
OrthoDB1362
GeneTree (enSembl)ENSG00000108582
Phylogenetic Trees/Animal Genes : TreeFamCPD
Homologs : HomoloGeneCPD
Homology/Alignments : Family Browser (UCSC)CPD
Gene fusions - Rearrangements
Fusion: TCGACPD 17q11.2 AATF 17q12 BRCA
Fusion: TCGACPD 17q11.2 ORMDL3 17q12 LUAD
Fusion: TCGACPD 17q11.2 PIGW 17q12 PRAD
Fusion: TCGACPD 17q11.2 SKAP1 17q21.32 BRCA
Fusion: TCGACPD 17q11.2 TBX2 17q23.2 BRCA
Fusion: TCGANUFIP2 17q11.2 CPD 17q11.2 PRAD
Polymorphisms : SNP, variants
NCBI Variation ViewerCPD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPD
dbVarCPD
ClinVarCPD
1000_GenomesCPD 
Exome Variant ServerCPD
ExAC (Exome Aggregation Consortium)CPD (select the gene name)
SNP (GeneSNP Utah)CPD
SNP : HGBaseCPD
Genetic variants : HAPMAPCPD
Genomic Variants (DGV)CPD [DGVbeta]
Mutations
ICGC Data PortalCPD 
TCGA Data PortalCPD 
Broad Tumor PortalCPD
OASIS PortalCPD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPD 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPD
DgiDB (Drug Gene Interaction Database)CPD
DoCM (Curated mutations)CPD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPD (select a term)
intoGenCPD
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:28707496-28796675
CONAN: Copy Number AnalysisCPD 
Mutations and Diseases : HGMDCPD
OMIM603102   
MedgenCPD
Genetic Testing Registry CPD
NextProtO75976 [Medical]
TSGene1362
GENETestsCPD
Huge Navigator CPD [HugePedia]  CPD [HugeCancerGEM]
snp3D : Map Gene to Disease1362
BioCentury BCIQCPD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1362
Chemical/Pharm GKB GenePA26823
Clinical trialCPD
Miscellaneous
canSAR (ICR)CPD (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPD
GoPubMedCPD
iHOPCPD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 17:40:59 CEST 2016

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