CPEB1 (cytoplasmic polyadenylation element binding protein 1)

2009-03-01  

Identity

HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
CPE-BP1,CPEB,CPEB-1,h-CPEB,hCPEB-1

Other Information

Locus ID:

NCBI: 64506
MIM: 607342
HGNC: 21744
Ensembl: ENSG00000214575

Variants:

dbSNP: 64506
ClinVar: 64506
TCGA: ENSG00000214575
COSMIC: CPEB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214575ENST00000567678H3BTE4
ENSG00000214575ENST00000568994H3BNX1
ENSG00000214575ENST00000569257H3BPD6
ENSG00000214575ENST00000611031A0A087X171
ENSG00000214575ENST00000611163Q9BZB8
ENSG00000214575ENST00000614918A0A087WXG7
ENSG00000214575ENST00000614977A0A087WUQ9
ENSG00000214575ENST00000615198Q9BZB8
ENSG00000214575ENST00000616959A0A087WVR7
ENSG00000214575ENST00000617462Q9BZB8
ENSG00000214575ENST00000617522Q9BZB8
ENSG00000214575ENST00000617958A0A024R214
ENSG00000214575ENST00000618449Q9BZB8
ENSG00000214575ENST00000620182Q9BZB8

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Dorso-ventral axis formationKEGGko04320
Progesterone-mediated oocyte maturationKEGGko04914
Dorso-ventral axis formationKEGGhsa04320
Progesterone-mediated oocyte maturationKEGGhsa04914
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114

References

Pubmed IDYearTitleCitations
157310062005The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules.124
200620642010Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.91
214788712011CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation.81
227276652012Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.56
191414772008CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation.50
234347542013CPEB1 coordinates alternative 3'-UTR formation with translational regulation.49
241414222013Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology.46
189231372009Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies.25
191615372009Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development.24
223340782012CPEB-mediated ZO-1 mRNA localization is required for epithelial tight-junction assembly and cell polarity.23

Citation

Dessen P

CPEB1 (cytoplasmic polyadenylation element binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50810/cpeb1