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CPEB2 (cytoplasmic polyadenylation element binding protein 2)

Identity

Other aliasCPE-BP2
CPEB-2
hCPEB-2
HGNC (Hugo) CPEB2
LocusID (NCBI) 132864
Atlas_Id 55640
Location 4p15.32  [Link to chromosome band 4p15]
Location_base_pair Starts at 15002674 and ends at 15070153 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CPEB2 (4p15.33) / CC2D2A (4p15.32)RPS24 (10q22.3) / CPEB2 (4p15.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPEB2   21745
Cards
Entrez_Gene (NCBI)CPEB2  132864  cytoplasmic polyadenylation element binding protein 2
AliasesCPE-BP2; CPEB-2; hCPEB-2
GeneCards (Weizmann)CPEB2
Ensembl hg19 (Hinxton)ENSG00000137449 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137449 [Gene_View]  chr4:15002674-15070153 [Contig_View]  CPEB2 [Vega]
ICGC DataPortalENSG00000137449
TCGA cBioPortalCPEB2
AceView (NCBI)CPEB2
Genatlas (Paris)CPEB2
WikiGenes132864
SOURCE (Princeton)CPEB2
Genetics Home Reference (NIH)CPEB2
Genomic and cartography
GoldenPath hg38 (UCSC)CPEB2  -     chr4:15002674-15070153 +  4p15.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CPEB2  -     4p15.32   [Description]    (hg19-Feb_2009)
EnsemblCPEB2 - 4p15.32 [CytoView hg19]  CPEB2 - 4p15.32 [CytoView hg38]
Mapping of homologs : NCBICPEB2 [Mapview hg19]  CPEB2 [Mapview hg38]
OMIM610605   
Gene and transcription
Genbank (Entrez)AK094566 AY247744 AY255519 BC103939 BC103940
RefSeq transcript (Entrez)NM_001177381 NM_001177382 NM_001177383 NM_001177384 NM_182485 NM_182646
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CPEB2
Cluster EST : UnigeneHs.656937 [ NCBI ]
CGAP (NCI)Hs.656937
Alternative Splicing GalleryENSG00000137449
Gene ExpressionCPEB2 [ NCBI-GEO ]   CPEB2 [ EBI - ARRAY_EXPRESS ]   CPEB2 [ SEEK ]   CPEB2 [ MEM ]
Gene Expression Viewer (FireBrowse)CPEB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)132864
GTEX Portal (Tissue expression)CPEB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5Q1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z5Q1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z5Q1
Splice isoforms : SwissVarQ7Z5Q1
PhosPhoSitePlusQ7Z5Q1
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)CEBP_ZZ    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)CEBP_ZZ (PF16366)    RRM_7 (PF16367)   
Domain families : Pfam (NCBI)pfam16366    pfam16367   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)CPEB2
DMDM Disease mutations132864
Blocks (Seattle)CPEB2
SuperfamilyQ7Z5Q1
Human Protein AtlasENSG00000137449
Peptide AtlasQ7Z5Q1
HPRD16744
IPIIPI00968087   IPI00816242   IPI00956327   IPI00815680   IPI00643285   IPI00815899   IPI00376209   IPI00787865   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5Q1
IntAct (EBI)Q7Z5Q1
FunCoupENSG00000137449
BioGRIDCPEB2
STRING (EMBL)CPEB2
ZODIACCPEB2
Ontologies - Pathways
QuickGOQ7Z5Q1
Ontology : AmiGOtranslation repressor activity, nucleic acid binding  translation repressor activity, nucleic acid binding  RNA binding  mRNA 3'-UTR binding  GTPase inhibitor activity  nucleus  cytoplasm  translation  translation factor activity, RNA binding  cellular response to insulin stimulus  negative regulation of GTPase activity  cellular response to oxidative stress  mRNA 3'-UTR AU-rich region binding  neuron projection  ribosome binding  ribosome binding  ribosomal large subunit binding  ribosomal small subunit binding  synapse  cellular response to arsenic-containing substance  cellular response to hypoxia  negative regulation of cytoplasmic translational elongation  messenger ribonucleoprotein complex  messenger ribonucleoprotein complex  negative regulation of cytoplasmic translation  
Ontology : EGO-EBItranslation repressor activity, nucleic acid binding  translation repressor activity, nucleic acid binding  RNA binding  mRNA 3'-UTR binding  GTPase inhibitor activity  nucleus  cytoplasm  translation  translation factor activity, RNA binding  cellular response to insulin stimulus  negative regulation of GTPase activity  cellular response to oxidative stress  mRNA 3'-UTR AU-rich region binding  neuron projection  ribosome binding  ribosome binding  ribosomal large subunit binding  ribosomal small subunit binding  synapse  cellular response to arsenic-containing substance  cellular response to hypoxia  negative regulation of cytoplasmic translational elongation  messenger ribonucleoprotein complex  messenger ribonucleoprotein complex  negative regulation of cytoplasmic translation  
NDEx NetworkCPEB2
Atlas of Cancer Signalling NetworkCPEB2
Wikipedia pathwaysCPEB2
Orthology - Evolution
OrthoDB132864
GeneTree (enSembl)ENSG00000137449
Phylogenetic Trees/Animal Genes : TreeFamCPEB2
HOVERGENQ7Z5Q1
HOGENOMQ7Z5Q1
Homologs : HomoloGeneCPEB2
Homology/Alignments : Family Browser (UCSC)CPEB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPEB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPEB2
dbVarCPEB2
ClinVarCPEB2
1000_GenomesCPEB2 
Exome Variant ServerCPEB2
ExAC (Exome Aggregation Consortium)CPEB2 (select the gene name)
Genetic variants : HAPMAP132864
Genomic Variants (DGV)CPEB2 [DGVbeta]
DECIPHERCPEB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCPEB2 
Mutations
ICGC Data PortalCPEB2 
TCGA Data PortalCPEB2 
Broad Tumor PortalCPEB2
OASIS PortalCPEB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPEB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPEB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPEB2
DgiDB (Drug Gene Interaction Database)CPEB2
DoCM (Curated mutations)CPEB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPEB2 (select a term)
intoGenCPEB2
Cancer3DCPEB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610605   
Orphanet
MedgenCPEB2
Genetic Testing Registry CPEB2
NextProtQ7Z5Q1 [Medical]
TSGene132864
GENETestsCPEB2
Target ValidationCPEB2
Huge Navigator CPEB2 [HugePedia]
snp3D : Map Gene to Disease132864
BioCentury BCIQCPEB2
ClinGenCPEB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD132864
Chemical/Pharm GKB GenePA134864048
Clinical trialCPEB2
Miscellaneous
canSAR (ICR)CPEB2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPEB2
EVEXCPEB2
GoPubMedCPEB2
iHOPCPEB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:29:24 CEST 2017

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