Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CPLX1 (complexin 1)

Identity

Alias_symbol (synonym)CPX-I
Other aliasCPX1
HGNC (Hugo) CPLX1
LocusID (NCBI) 10815
Atlas_Id 56183
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 778745 and ends at 819945 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNB1 (1p36.33) / CPLX1 (4p16.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPLX1   2309
Cards
Entrez_Gene (NCBI)CPLX1  10815  complexin 1
AliasesCPX-I; CPX1
GeneCards (Weizmann)CPLX1
Ensembl hg19 (Hinxton)ENSG00000168993 [Gene_View]  chr4:778745-819945 [Contig_View]  CPLX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168993 [Gene_View]  chr4:778745-819945 [Contig_View]  CPLX1 [Vega]
ICGC DataPortalENSG00000168993
TCGA cBioPortalCPLX1
AceView (NCBI)CPLX1
Genatlas (Paris)CPLX1
WikiGenes10815
SOURCE (Princeton)CPLX1
Genetics Home Reference (NIH)CPLX1
Genomic and cartography
GoldenPath hg19 (UCSC)CPLX1  -     chr4:778745-819945 -  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPLX1  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblCPLX1 - 4p16.3 [CytoView hg19]  CPLX1 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBICPLX1 [Mapview hg19]  CPLX1 [Mapview hg38]
OMIM194190   605032   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_006651
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CPLX1
Cluster EST : UnigeneHs.478930 [ NCBI ]
CGAP (NCI)Hs.478930
Alternative Splicing GalleryENSG00000168993
Gene ExpressionCPLX1 [ NCBI-GEO ]   CPLX1 [ EBI - ARRAY_EXPRESS ]   CPLX1 [ SEEK ]   CPLX1 [ MEM ]
Gene Expression Viewer (FireBrowse)CPLX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10815
GTEX Portal (Tissue expression)CPLX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14810   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14810  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14810
Splice isoforms : SwissVarO14810
PhosPhoSitePlusO14810
Domains : Interpro (EBI)Synaphin   
Domain families : Pfam (Sanger)Synaphin (PF05835)   
Domain families : Pfam (NCBI)pfam05835   
Conserved Domain (NCBI)CPLX1
DMDM Disease mutations10815
Blocks (Seattle)CPLX1
PDB (SRS)3RK3    3RL0   
PDB (PDBSum)3RK3    3RL0   
PDB (IMB)3RK3    3RL0   
PDB (RSDB)3RK3    3RL0   
Structural Biology KnowledgeBase3RK3    3RL0   
SCOP (Structural Classification of Proteins)3RK3    3RL0   
CATH (Classification of proteins structures)3RK3    3RL0   
SuperfamilyO14810
Human Protein AtlasENSG00000168993
Peptide AtlasO14810
HPRD09233
IPIIPI00396023   IPI00964829   IPI00966929   IPI00966607   
Protein Interaction databases
DIP (DOE-UCLA)O14810
IntAct (EBI)O14810
FunCoupENSG00000168993
BioGRIDCPLX1
STRING (EMBL)CPLX1
ZODIACCPLX1
Ontologies - Pathways
QuickGOO14810
Ontology : AmiGOneurotransmitter transporter activity  cytosol  exocytosis  chemical synaptic transmission  neurotransmitter secretion  glutamate secretion  synaptic vesicle exocytosis  syntaxin-1 binding  regulation of exocytosis  insulin secretion  dendrite  neuronal cell body  terminal bouton  synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex  synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex  
Ontology : EGO-EBIneurotransmitter transporter activity  cytosol  exocytosis  chemical synaptic transmission  neurotransmitter secretion  glutamate secretion  synaptic vesicle exocytosis  syntaxin-1 binding  regulation of exocytosis  insulin secretion  dendrite  neuronal cell body  terminal bouton  synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex  synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex  
Pathways : KEGGSynaptic vesicle cycle   
NDEx NetworkCPLX1
Atlas of Cancer Signalling NetworkCPLX1
Wikipedia pathwaysCPLX1
Orthology - Evolution
OrthoDB10815
GeneTree (enSembl)ENSG00000168993
Phylogenetic Trees/Animal Genes : TreeFamCPLX1
HOVERGENO14810
HOGENOMO14810
Homologs : HomoloGeneCPLX1
Homology/Alignments : Family Browser (UCSC)CPLX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPLX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPLX1
dbVarCPLX1
ClinVarCPLX1
1000_GenomesCPLX1 
Exome Variant ServerCPLX1
ExAC (Exome Aggregation Consortium)CPLX1 (select the gene name)
Genetic variants : HAPMAP10815
Genomic Variants (DGV)CPLX1 [DGVbeta]
DECIPHER (Syndromes)4:778745-819945  ENSG00000168993
CONAN: Copy Number AnalysisCPLX1 
Mutations
ICGC Data PortalCPLX1 
TCGA Data PortalCPLX1 
Broad Tumor PortalCPLX1
OASIS PortalCPLX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPLX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPLX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPLX1
DgiDB (Drug Gene Interaction Database)CPLX1
DoCM (Curated mutations)CPLX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPLX1 (select a term)
intoGenCPLX1
Cancer3DCPLX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM194190    605032   
Orphanet
MedgenCPLX1
Genetic Testing Registry CPLX1
NextProtO14810 [Medical]
TSGene10815
GENETestsCPLX1
Huge Navigator CPLX1 [HugePedia]
snp3D : Map Gene to Disease10815
BioCentury BCIQCPLX1
ClinGenCPLX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10815
Chemical/Pharm GKB GenePA26826
Clinical trialCPLX1
Miscellaneous
canSAR (ICR)CPLX1 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPLX1
EVEXCPLX1
GoPubMedCPLX1
iHOPCPLX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:01:32 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.