Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1369
MIM: 603103
HGNC: 2312
Ensembl: ENSG00000120054
Variants:
dbSNP: 1369
ClinVar: 1369
TCGA: ENSG00000120054
COSMIC: CPN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120054 | ENST00000370418 | P15169 |
| ENSG00000120054 | ENST00000441382 | B1AP58 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Peptide hormone metabolism | REACTOME | R-HSA-2980736 |
| Insulin processing | REACTOME | R-HSA-264876 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 23000409 | 2012 | Binding of carboxypeptidase N to fibrinogen and fibrin. | 5 |
| 23000409 | 2012 | Binding of carboxypeptidase N to fibrinogen and fibrin. | 5 |
| 21052031 | 2011 | Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. | 15 |
| 21052031 | 2011 | Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. | 15 |
| 20200978 | 2010 | Replication of previous genome-wide association studies of bone mineral density in premenopausal American women. | 8 |
| 20648472 | 2010 | PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease. | 147 |
| 20200978 | 2010 | Replication of previous genome-wide association studies of bone mineral density in premenopausal American women. | 8 |
| 20648472 | 2010 | PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease. | 147 |
| 19010784 | 2009 | Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. | 43 |
| 19010784 | 2009 | Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. | 43 |
| 18940312 | 2008 | Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. | 193 |
| 18940312 | 2008 | Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. | 193 |
| 18039526 | 2007 | Structure and function of human plasma carboxypeptidase N, the anaphylatoxin inactivator. | 33 |
| 18039526 | 2007 | Structure and function of human plasma carboxypeptidase N, the anaphylatoxin inactivator. | 33 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
Citation
Dessen P
CPN1 (carboxypeptidase N subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47373/cpn1
