CPO (carboxypeptidase O)

2014-11-01  

Identity

HGNC
CPO
LOCATION
2q33.3
LOCUSID
130749
ALIAS
-

Other Information

Locus ID:

NCBI: 130749
MIM: 609563
HGNC: 21011
Ensembl: ENSG00000144410

Variants:

dbSNP: 130749
ClinVar: 130749
TCGA: ENSG00000144410
COSMIC: CPO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144410ENST00000272852Q8IVL8

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
219210282011Carboxypeptidase O is a glycosylphosphatidylinositol-anchored intestinal peptidase with acidic amino acid specificity.12
296364172018Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.1

Citation

Dessen P

CPO (carboxypeptidase O)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62060/cpo