Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CPOX (coproporphyrinogen oxidase)

Identity

Alias_namesCPO
coproporphyrinogen oxidase (coproporphyria
Alias_symbol (synonym)CPX
HCP
Other alias
HGNC (Hugo) CPOX
LocusID (NCBI) 1371
Atlas_Id 52614
Location 3q11.2  [Link to chromosome band 3q11]
Location_base_pair Starts at 98298290 and ends at 98312455 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPOX   2321
LRG (Locus Reference Genomic)LRG_1077
Cards
Entrez_Gene (NCBI)CPOX  1371  coproporphyrinogen oxidase
AliasesCPO; CPX; HCP
GeneCards (Weizmann)CPOX
Ensembl hg19 (Hinxton)ENSG00000080819 [Gene_View]  chr3:98298290-98312455 [Contig_View]  CPOX [Vega]
Ensembl hg38 (Hinxton)ENSG00000080819 [Gene_View]  chr3:98298290-98312455 [Contig_View]  CPOX [Vega]
ICGC DataPortalENSG00000080819
TCGA cBioPortalCPOX
AceView (NCBI)CPOX
Genatlas (Paris)CPOX
WikiGenes1371
SOURCE (Princeton)CPOX
Genetics Home Reference (NIH)CPOX
Genomic and cartography
GoldenPath hg19 (UCSC)CPOX  -     chr3:98298290-98312455 -  3q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPOX  -     3q11.2   [Description]    (hg38-Dec_2013)
EnsemblCPOX - 3q11.2 [CytoView hg19]  CPOX - 3q11.2 [CytoView hg38]
Mapping of homologs : NCBICPOX [Mapview hg19]  CPOX [Mapview hg38]
OMIM121300   612732   
Gene and transcription
Genbank (Entrez)AK223481 AK290140 AK299692 BC017210 BC023551
RefSeq transcript (Entrez)NM_000097
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_015994 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)CPOX
Cluster EST : UnigeneHs.476982 [ NCBI ]
CGAP (NCI)Hs.476982
Alternative Splicing GalleryENSG00000080819
Gene ExpressionCPOX [ NCBI-GEO ]   CPOX [ EBI - ARRAY_EXPRESS ]   CPOX [ SEEK ]   CPOX [ MEM ]
Gene Expression Viewer (FireBrowse)CPOX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1371
GTEX Portal (Tissue expression)CPOX
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36551   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36551  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36551
Splice isoforms : SwissVarP36551
Catalytic activity : Enzyme1.3.3.3 [ Enzyme-Expasy ]   1.3.3.31.3.3.3 [ IntEnz-EBI ]   1.3.3.3 [ BRENDA ]   1.3.3.3 [ KEGG ]   
PhosPhoSitePlusP36551
Domaine pattern : Prosite (Expaxy)COPROGEN_OXIDASE (PS01021)   
Domains : Interpro (EBI)Coprogen_oxidase_aer    Coprogen_oxidase_CS   
Domain families : Pfam (Sanger)Coprogen_oxidas (PF01218)   
Domain families : Pfam (NCBI)pfam01218   
Conserved Domain (NCBI)CPOX
DMDM Disease mutations1371
Blocks (Seattle)CPOX
PDB (SRS)2AEX   
PDB (PDBSum)2AEX   
PDB (IMB)2AEX   
PDB (RSDB)2AEX   
Structural Biology KnowledgeBase2AEX   
SCOP (Structural Classification of Proteins)2AEX   
CATH (Classification of proteins structures)2AEX   
SuperfamilyP36551
Human Protein AtlasENSG00000080819
Peptide AtlasP36551
HPRD00417
IPIIPI00093057   IPI00963892   IPI00964195   
Protein Interaction databases
DIP (DOE-UCLA)P36551
IntAct (EBI)P36551
FunCoupENSG00000080819
BioGRIDCPOX
STRING (EMBL)CPOX
ZODIACCPOX
Ontologies - Pathways
QuickGOP36551
Ontology : AmiGOcoproporphyrinogen oxidase activity  structural constituent of eye lens  cytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial intermembrane space  protoporphyrinogen IX biosynthetic process  heme biosynthetic process  response to iron ion  response to lead ion  response to insecticide  protein homodimerization activity  response to arsenic-containing substance  response to methylmercury  oxidation-reduction process  
Ontology : EGO-EBIcoproporphyrinogen oxidase activity  structural constituent of eye lens  cytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial intermembrane space  protoporphyrinogen IX biosynthetic process  heme biosynthetic process  response to iron ion  response to lead ion  response to insecticide  protein homodimerization activity  response to arsenic-containing substance  response to methylmercury  oxidation-reduction process  
Pathways : BIOCARTAHemoglobin's Chaperone [Genes]   
Pathways : KEGGPorphyrin and chlorophyll metabolism   
NDEx NetworkCPOX
Atlas of Cancer Signalling NetworkCPOX
Wikipedia pathwaysCPOX
Orthology - Evolution
OrthoDB1371
GeneTree (enSembl)ENSG00000080819
Phylogenetic Trees/Animal Genes : TreeFamCPOX
HOVERGENP36551
HOGENOMP36551
Homologs : HomoloGeneCPOX
Homology/Alignments : Family Browser (UCSC)CPOX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPOX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPOX
dbVarCPOX
ClinVarCPOX
1000_GenomesCPOX 
Exome Variant ServerCPOX
ExAC (Exome Aggregation Consortium)CPOX (select the gene name)
Genetic variants : HAPMAP1371
Genomic Variants (DGV)CPOX [DGVbeta]
DECIPHER (Syndromes)3:98298290-98312455  ENSG00000080819
CONAN: Copy Number AnalysisCPOX 
Mutations
ICGC Data PortalCPOX 
TCGA Data PortalCPOX 
Broad Tumor PortalCPOX
OASIS PortalCPOX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPOX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPOX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CPOX
DgiDB (Drug Gene Interaction Database)CPOX
DoCM (Curated mutations)CPOX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPOX (select a term)
intoGenCPOX
Cancer3DCPOX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM121300    612732   
Orphanet11299   
MedgenCPOX
Genetic Testing Registry CPOX
NextProtP36551 [Medical]
TSGene1371
GENETestsCPOX
Huge Navigator CPOX [HugePedia]
snp3D : Map Gene to Disease1371
BioCentury BCIQCPOX
ClinGenCPOX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1371
Chemical/Pharm GKB GenePA134979958
Clinical trialCPOX
Miscellaneous
canSAR (ICR)CPOX (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPOX
EVEXCPOX
GoPubMedCPOX
iHOPCPOX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:57:28 CEST 2017

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