Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CPSF7 (cleavage and polyadenylation specific factor 7, 59kDa)

Identity

Alias_namescleavage and polyadenylation specific factor 7, 59kDa
Alias_symbol (synonym)FLJ12529
Other aliasCFIm59
HGNC (Hugo) CPSF7
LocusID (NCBI) 79869
Atlas_Id 62065
Location 11q12.2  [Link to chromosome band 11q12]
Location_base_pair Starts at 61170120 and ends at 61197464 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CPSF7 (11q12.2) / CHN2 (7p14.3)CPSF7 (11q12.2) / DNAJB6 (7q36.3)CPSF7 (11q12.2) / EVL (14q32.2)
CPSF7 (11q12.2) / LOC645206 ()MAPK8IP1 (11p11.2) / CPSF7 (11q12.2)TNNT2 (1q32.1) / CPSF7 (11q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CPSF7   30098
Cards
Entrez_Gene (NCBI)CPSF7  79869  cleavage and polyadenylation specific factor 7, 59kDa
AliasesCFIm59
GeneCards (Weizmann)CPSF7
Ensembl hg19 (Hinxton)ENSG00000149532 [Gene_View]  chr11:61170120-61197464 [Contig_View]  CPSF7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000149532 [Gene_View]  chr11:61170120-61197464 [Contig_View]  CPSF7 [Vega]
ICGC DataPortalENSG00000149532
TCGA cBioPortalCPSF7
AceView (NCBI)CPSF7
Genatlas (Paris)CPSF7
WikiGenes79869
SOURCE (Princeton)CPSF7
Genetics Home Reference (NIH)CPSF7
Genomic and cartography
GoldenPath hg19 (UCSC)CPSF7  -     chr11:61170120-61197464 -  11q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CPSF7  -     11q12.2   [Description]    (hg38-Dec_2013)
EnsemblCPSF7 - 11q12.2 [CytoView hg19]  CPSF7 - 11q12.2 [CytoView hg38]
Mapping of homologs : NCBICPSF7 [Mapview hg19]  CPSF7 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ275970 AK022591 AK092037 AK096343 AK294578
RefSeq transcript (Entrez)NM_001136040 NM_001142565 NM_024811
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)CPSF7
Cluster EST : UnigeneHs.718984 [ NCBI ]
CGAP (NCI)Hs.718984
Alternative Splicing GalleryENSG00000149532
Gene ExpressionCPSF7 [ NCBI-GEO ]   CPSF7 [ EBI - ARRAY_EXPRESS ]   CPSF7 [ SEEK ]   CPSF7 [ MEM ]
Gene Expression Viewer (FireBrowse)CPSF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79869
GTEX Portal (Tissue expression)CPSF7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N684   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N684  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N684
Splice isoforms : SwissVarQ8N684
PhosPhoSitePlusQ8N684
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)CPSF7
DMDM Disease mutations79869
Blocks (Seattle)CPSF7
PDB (SRS)3N9U   
PDB (PDBSum)3N9U   
PDB (IMB)3N9U   
PDB (RSDB)3N9U   
Structural Biology KnowledgeBase3N9U   
SCOP (Structural Classification of Proteins)3N9U   
CATH (Classification of proteins structures)3N9U   
SuperfamilyQ8N684
Human Protein AtlasENSG00000149532
Peptide AtlasQ8N684
HPRD16906
IPIIPI00550821   IPI00719106   IPI00915356   IPI00921501   IPI00927669   IPI00927882   IPI00926271   IPI01014376   IPI01014911   IPI01013482   IPI01015697   IPI01014281   IPI01013082   IPI01011618   IPI01009370   IPI00926462   IPI01010753   
Protein Interaction databases
DIP (DOE-UCLA)Q8N684
IntAct (EBI)Q8N684
FunCoupENSG00000149532
BioGRIDCPSF7
STRING (EMBL)CPSF7
ZODIACCPSF7
Ontologies - Pathways
QuickGOQ8N684
Ontology : AmiGOnucleotide binding  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  mRNA cleavage factor complex  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  RNA splicing  gene expression  membrane  mRNA 3'-end processing  poly(A) RNA binding  protein tetramerization  
Ontology : EGO-EBInucleotide binding  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  mRNA cleavage factor complex  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  RNA splicing  gene expression  membrane  mRNA 3'-end processing  poly(A) RNA binding  protein tetramerization  
Pathways : KEGGmRNA surveillance pathway   
NDEx NetworkCPSF7
Atlas of Cancer Signalling NetworkCPSF7
Wikipedia pathwaysCPSF7
Orthology - Evolution
OrthoDB79869
GeneTree (enSembl)ENSG00000149532
Phylogenetic Trees/Animal Genes : TreeFamCPSF7
HOVERGENQ8N684
HOGENOMQ8N684
Homologs : HomoloGeneCPSF7
Homology/Alignments : Family Browser (UCSC)CPSF7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCPSF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CPSF7
dbVarCPSF7
ClinVarCPSF7
1000_GenomesCPSF7 
Exome Variant ServerCPSF7
ExAC (Exome Aggregation Consortium)CPSF7 (select the gene name)
Genetic variants : HAPMAP79869
Genomic Variants (DGV)CPSF7 [DGVbeta]
DECIPHER (Syndromes)11:61170120-61197464  ENSG00000149532
CONAN: Copy Number AnalysisCPSF7 
Mutations
ICGC Data PortalCPSF7 
TCGA Data PortalCPSF7 
Broad Tumor PortalCPSF7
OASIS PortalCPSF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCPSF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCPSF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CPSF7
DgiDB (Drug Gene Interaction Database)CPSF7
DoCM (Curated mutations)CPSF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CPSF7 (select a term)
intoGenCPSF7
Cancer3DCPSF7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCPSF7
Genetic Testing Registry CPSF7
NextProtQ8N684 [Medical]
TSGene79869
GENETestsCPSF7
Huge Navigator CPSF7 [HugePedia]
snp3D : Map Gene to Disease79869
BioCentury BCIQCPSF7
ClinGenCPSF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79869
Chemical/Pharm GKB GenePA165543380
Clinical trialCPSF7
Miscellaneous
canSAR (ICR)CPSF7 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCPSF7
EVEXCPSF7
GoPubMedCPSF7
iHOPCPSF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:00:15 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.