CPSF7 (cleavage and polyadenylation specific factor 7)

2014-11-01  

Identity

HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
CFIm59
FUSION GENES

Other Information

Locus ID:

NCBI: 79869
HGNC: 30098
Ensembl: ENSG00000149532

Variants:

dbSNP: 79869
ClinVar: 79869
TCGA: ENSG00000149532
COSMIC: CPSF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149532ENST00000340437Q8N684
ENSG00000149532ENST00000394888Q8N684
ENSG00000149532ENST00000413184C9JM38
ENSG00000149532ENST00000413232J3QT54
ENSG00000149532ENST00000439958Q8N684
ENSG00000149532ENST00000448745Q8N684
ENSG00000149532ENST00000449811C9J286
ENSG00000149532ENST00000450000C9J323
ENSG00000149532ENST00000477890F5H669
ENSG00000149532ENST00000535222F5H2K8
ENSG00000149532ENST00000536145F5H6A8
ENSG00000149532ENST00000536548F5H6P5
ENSG00000149532ENST00000537162F5H6P5
ENSG00000149532ENST00000539952F5H047
ENSG00000149532ENST00000541963F5H1W4
ENSG00000149532ENST00000543545F5H5B7
ENSG00000149532ENST00000544585F5H6M0
ENSG00000149532ENST00000544990F5GXA3
ENSG00000149532ENST00000626926F5H6P5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Processing of Capped Intronless Pre-mRNAREACTOMER-HSA-75067
Processing of Intronless Pre-mRNAsREACTOMER-HSA-77595

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
292760852018Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.36
206959052010Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation.26
318379822020CPSF7 regulates liver cancer growth and metastasis by facilitating WWP2-FL and targeting the WWP2/PTEN/AKT signaling pathway.1

Citation

Dessen P

CPSF7 (cleavage and polyadenylation specific factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62065/cpsf7