Identity
HGNC
LOCATION
11q13.3
LOCUSID
ALIAS
CPT1,CPT1-L,L-CPT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1374
MIM: 600528
HGNC: 2328
Ensembl: ENSG00000110090
Variants:
dbSNP: 1374
ClinVar: 1374
TCGA: ENSG00000110090
COSMIC: CPT1A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38494680 | 2024 | CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells. | 0 |
| 38767438 | 2024 | Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase-1A-induced lipid metabolism in diabetic nephropathy. | 1 |
| 38823763 | 2024 | CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer. | 0 |
| 38904677 | 2024 | CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation. | 0 |
| 38494680 | 2024 | CPT1A mediates the succinylation of SP5 which activates transcription of PDPK1 to promote the viability and glycolysis of prostate cancer cells. | 0 |
| 38767438 | 2024 | Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase-1A-induced lipid metabolism in diabetic nephropathy. | 1 |
| 38823763 | 2024 | CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer. | 0 |
| 38904677 | 2024 | CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation. | 0 |
| 36702079 | 2023 | CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia. | 6 |
| 36735704 | 2023 | The impact of variance in carnitine palmitoyltransferase-1 expression on breast cancer prognosis is stratified by clinical and anthropometric factors. | 2 |
| 36800272 | 2023 | DNA Methylation Near CPT1A and Changes in Triglyceride-rich Lipoproteins in Response to Weight-loss Diet Interventions. | 6 |
| 37249337 | 2023 | NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation. | 1 |
| 37291333 | 2023 | Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer. | 5 |
| 37722058 | 2023 | CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing. | 5 |
| 37891690 | 2023 | Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus. | 2 |
Citation
Dessen P
CPT1A (carnitine palmitoyltransferase 1A)
Atlas Genet Cytogenet Oncol Haematol. 2008-04-01
Online version: http://atlasgeneticsoncology.org/gene/50088/cpt1a
