| Nomenclature |
|---|
| HGNC (Hugo) | CREB3L1 18856 |
| Cards |
|---|
| Entrez_Gene (NCBI) | CREB3L1 90993 cAMP responsive element binding protein 3 like 1 |
| Aliases | OASIS; OI16 |
| GeneCards (Weizmann) | CREB3L1 |
| Ensembl hg19 (Hinxton) | ENSG00000157613 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000157613 [Gene_View] ENSG00000157613 [Sequence] chr11:46277662-46321394 [Contig_View] CREB3L1 [Vega] |
| ICGC DataPortal | ENSG00000157613 |
| TCGA cBioPortal | CREB3L1 |
| AceView (NCBI) | CREB3L1 |
| Genatlas (Paris) | CREB3L1 |
| WikiGenes | 90993 |
| SOURCE (Princeton) | CREB3L1 |
| Genetics Home Reference (NIH) | CREB3L1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | CREB3L1 - chr11:46277662-46321394 + 11p11.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | CREB3L1 - 11p11.2 [Description] (hg19-Feb_2009) |
| GoldenPath | CREB3L1 - 11p11.2 [CytoView hg19] CREB3L1 - 11p11.2 [CytoView hg38] |
| ImmunoBase | ENSG00000157613 |
| genome Data Viewer NCBI | CREB3L1 [Mapview hg19] |
| OMIM | 616215 616229 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB063321 AF055009 AK075538 AK314072 BC014097 |
| RefSeq transcript (Entrez) | NM_052854 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | CREB3L1 |
| Alternative Splicing Gallery | ENSG00000157613 |
| Gene Expression | CREB3L1 [ NCBI-GEO ] CREB3L1 [ EBI - ARRAY_EXPRESS ]
CREB3L1 [ SEEK ] CREB3L1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | CREB3L1 [ Firebrowse - Broad ] |
| Genevisible | Expression of CREB3L1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 90993 |
| GTEX Portal (Tissue expression) | CREB3L1 |
| Human Protein Atlas | ENSG00000157613-CREB3L1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q96BA8 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q96BA8 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q96BA8 |
| Splice isoforms : SwissVar | Q96BA8 |
| PhosPhoSitePlus | Q96BA8 |
| Domaine pattern : Prosite (Expaxy) | BZIP (PS50217) BZIP_BASIC (PS00036) |
| Domains : Interpro (EBI) | bZIP Leuzip_CREB OASIS |
| Domain families : Pfam (Sanger) | bZIP_1 (PF00170) |
| Domain families : Pfam (NCBI) | pfam00170 |
| Domain families : Smart (EMBL) | BRLZ (SM00338) |
| Conserved Domain (NCBI) | CREB3L1 |
| DMDM Disease mutations | 90993 |
| Blocks (Seattle) | CREB3L1 |
| Superfamily | Q96BA8 |
| Human Protein Atlas [tissue] | ENSG00000157613-CREB3L1 [tissue] |
| Peptide Atlas | Q96BA8 |
| HPRD | 16751 |
| IPI | IPI00303434 IPI00848028 IPI00975566 IPI00976052 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q96BA8 |
| IntAct (EBI) | Q96BA8 |
| FunCoup | ENSG00000157613 |
| BioGRID | CREB3L1 |
| STRING (EMBL) | CREB3L1 |
| ZODIAC | CREB3L1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q96BA8 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific osteoblast differentiation chromatin binding protein binding nucleus nucleus endoplasmic reticulum endoplasmic reticulum membrane multicellular organism development negative regulation of gene expression membrane integral component of membrane viral process endoplasmic reticulum unfolded protein response positive regulation of collagen biosynthetic process cAMP response element binding cAMP response element binding negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of transcription, DNA-templated SMAD binding extracellular matrix constituent secretion negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of sprouting angiogenesis positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific osteoblast differentiation chromatin binding protein binding nucleus nucleus endoplasmic reticulum endoplasmic reticulum membrane multicellular organism development negative regulation of gene expression membrane integral component of membrane viral process endoplasmic reticulum unfolded protein response positive regulation of collagen biosynthetic process cAMP response element binding cAMP response element binding negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of transcription, DNA-templated SMAD binding extracellular matrix constituent secretion negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of sprouting angiogenesis positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress |
| Pathways : KEGG | PI3K-Akt signaling pathway Adrenergic signaling in cardiomyocytes TNF signaling pathway Cholinergic synapse Dopaminergic synapse Insulin secretion Estrogen signaling pathway Melanogenesis Thyroid hormone synthesis Vasopressin-regulated water reabsorption Huntington's disease Cocaine addiction Amphetamine addiction Alcoholism Hepatitis B Viral carcinogenesis Prostate cancer |
| NDEx Network | CREB3L1 |
| Atlas of Cancer Signalling Network | CREB3L1 |
| Wikipedia pathways | CREB3L1 |
| Orthology - Evolution |
|---|
| OrthoDB | 90993 |
| GeneTree (enSembl) | ENSG00000157613 |
| Phylogenetic Trees/Animal Genes : TreeFam | CREB3L1 |
| HOGENOM | Q96BA8 |
| Homologs : HomoloGene | CREB3L1 |
| Homology/Alignments : Family Browser (UCSC) | CREB3L1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | EWSR1/CREB3L1 [22q12.2/11p11.2] |
| Fusion : Mitelman | FUS/CREB3L1 [16p11.2/11p11.2] |
| |
| Fusion : Quiver | CREB3L1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | CREB3L1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | CREB3L1 |
| dbVar | CREB3L1 |
| ClinVar | CREB3L1 |
| 1000_Genomes | CREB3L1 |
| Exome Variant Server | CREB3L1 |
| GNOMAD Browser | ENSG00000157613 |
| Varsome Browser | CREB3L1 |
| Genetic variants : HAPMAP | 90993 |
| Genomic Variants (DGV) | CREB3L1 [DGVbeta] |
| DECIPHER | CREB3L1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | CREB3L1 |
| Mutations |
|---|
| ICGC Data Portal | CREB3L1 |
| TCGA Data Portal | CREB3L1 |
| Broad Tumor Portal | CREB3L1 |
| OASIS Portal | CREB3L1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | CREB3L1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | CREB3L1 |
| Mutations and Diseases : HGMD | CREB3L1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | Osteogenesis Imperfecta Variant Database |
| BioMuta | search CREB3L1 |
| DgiDB (Drug Gene Interaction Database) | CREB3L1 |
| DoCM (Curated mutations) | CREB3L1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | CREB3L1 (select a term) |
| intoGen | CREB3L1 |
| Cancer3D | CREB3L1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 616215 616229 |
| Orphanet | 18793 11147 |
| DisGeNET | CREB3L1 |
| Medgen | CREB3L1 |
| Genetic Testing Registry | CREB3L1
|
| NextProt | Q96BA8 [Medical] |
| TSGene | 90993 |
| GENETests | CREB3L1 |
| Target Validation | CREB3L1 |
| Huge Navigator |
CREB3L1 [HugePedia] |
| snp3D : Map Gene to Disease | 90993 |
| BioCentury BCIQ | CREB3L1 |
| ClinGen | CREB3L1 |
| Clinical trials, drugs, therapy |
|---|
| Protein Interactions : CTD | 90993 |
| Pharm GKB Gene | PA134960108 |
| Clinical trial | CREB3L1 |
| Miscellaneous |
|---|
| canSAR (ICR) | CREB3L1 (select the gene name) |
| Harmonizome | CREB3L1 |
| DataMed Index | CREB3L1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 51 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | CREB3L1 |
| EVEX | CREB3L1 |
| GoPubMed | CREB3L1 |
