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CREB5 (cAMP responsive element binding protein 5)

Identity

Alias (NCBI)CRE-BPA
CREB-5
CREBPA
HGNC (Hugo) CREB5
HGNC Alias symbH_GS165L15.1
CRE-BPA
HGNC Alias namecAMP response element binding protein CRE-Bpa
LocusID (NCBI) 9586
Atlas_Id 54898
Location 7p15.1  [Link to chromosome band 7p15]
Location_base_pair Starts at 28299321 and ends at 28825894 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID5B (10q21.2)::CREB5 (7p15.1)CCND2 (12p13.32)::CREB5 (7p15.1)CREB5 (7p15.1)::CD74 (5q32)
CREB5 (7p15.1)::KCNH2 (7q36.1)CREB5 (7p15.1)::NUDCD2 (5q34)CREB5 (7p15.1)::USP42 (7p22.1)
ELF4 (Xq26.1)::CREB5 (7p15.1)FAM188B (7p14.3)::CREB5 (7p15.1)ZNF711 (Xq21.1)::CREB5 (7p15.1)
CREB5 7p15.1::KCNH2 7q36.1CREB5 7p15.1::USP42 7p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CREB5   16844
Cards
Entrez_Gene (NCBI)CREB5    cAMP responsive element binding protein 5
AliasesCRE-BPA; CREB-5; CREBPA
GeneCards (Weizmann)CREB5
Ensembl hg19 (Hinxton)ENSG00000146592 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146592 [Gene_View]  ENSG00000146592 [Sequence]  chr7:28299321-28825894 [Contig_View]  CREB5 [Vega]
ICGC DataPortalENSG00000146592
TCGA cBioPortalCREB5
AceView (NCBI)CREB5
Genatlas (Paris)CREB5
SOURCE (Princeton)CREB5
Genetics Home Reference (NIH)CREB5
Genomic and cartography
GoldenPath hg38 (UCSC)CREB5  -     chr7:28299321-28825894 +  7p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CREB5  -     7p15.1   [Description]    (hg19-Feb_2009)
GoldenPathCREB5 - 7p15.1 [CytoView hg19]  CREB5 - 7p15.1 [CytoView hg38]
ImmunoBaseENSG00000146592
Genome Data Viewer NCBICREB5 [Mapview hg19]  
OMIM618262   
Gene and transcription
Genbank (Entrez)AB209262 AB451409 AK057151 AK292916 AK298121
RefSeq transcript (Entrez)NM_001011666 NM_004904 NM_182898 NM_182899
Consensus coding sequences : CCDS (NCBI)CREB5
Gene ExpressionCREB5 [ NCBI-GEO ]   CREB5 [ EBI - ARRAY_EXPRESS ]   CREB5 [ SEEK ]   CREB5 [ MEM ]
Gene Expression Viewer (FireBrowse)CREB5 [ Firebrowse - Broad ]
GenevisibleExpression of CREB5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9586
GTEX Portal (Tissue expression)CREB5
Human Protein AtlasENSG00000146592-CREB5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02930   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02930  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02930
PhosPhoSitePlusQ02930
Domaine pattern : Prosite (Expaxy)BZIP (PS50217)    BZIP_BASIC (PS00036)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)bZIP    TF_CRE-BP1-typ    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)bZIP_1 (PF00170)   
Domain families : Pfam (NCBI)pfam00170   
Domain families : Smart (EMBL)BRLZ (SM00338)  
Conserved Domain (NCBI)CREB5
SuperfamilyQ02930
AlphaFold pdb e-kbQ02930   
Human Protein Atlas [tissue]ENSG00000146592-CREB5 [tissue]
HPRD09896
Protein Interaction databases
DIP (DOE-UCLA)Q02930
IntAct (EBI)Q02930
BioGRIDCREB5
STRING (EMBL)CREB5
ZODIACCREB5
Ontologies - Pathways
QuickGOQ02930
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  regulation of transcription by RNA polymerase II  cAMP response element binding  positive regulation of transcription, DNA-templated  metal ion binding  extracellular exosome  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  regulation of transcription by RNA polymerase II  cAMP response element binding  positive regulation of transcription, DNA-templated  metal ion binding  extracellular exosome  sequence-specific double-stranded DNA binding  
Pathways : KEGGKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION    KEGG_HUNTINGTONS_DISEASE    KEGG_PROSTATE_CANCER   
NDEx NetworkCREB5
Atlas of Cancer Signalling NetworkCREB5
Wikipedia pathwaysCREB5
Orthology - Evolution
OrthoDB9586
GeneTree (enSembl)ENSG00000146592
Phylogenetic Trees/Animal Genes : TreeFamCREB5
Homologs : HomoloGeneCREB5
Homology/Alignments : Family Browser (UCSC)CREB5
Gene fusions - Rearrangements
Fusion : MitelmanCREB5::KCNH2 [7p15.1/7q36.1]  
Fusion : MitelmanCREB5::USP42 [7p15.1/7p22.1]  
Fusion : QuiverCREB5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCREB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CREB5
dbVarCREB5
ClinVarCREB5
MonarchCREB5
1000_GenomesCREB5 
Exome Variant ServerCREB5
GNOMAD BrowserENSG00000146592
Varsome BrowserCREB5
ACMGCREB5 variants
VarityQ02930
Genomic Variants (DGV)CREB5 [DGVbeta]
DECIPHERCREB5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCREB5 
Mutations
ICGC Data PortalCREB5 
TCGA Data PortalCREB5 
Broad Tumor PortalCREB5
OASIS PortalCREB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCREB5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCREB5
Mutations and Diseases : HGMDCREB5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCREB5
DgiDB (Drug Gene Interaction Database)CREB5
DoCM (Curated mutations)CREB5
CIViC (Clinical Interpretations of Variants in Cancer)CREB5
Cancer3DCREB5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618262   
Orphanet
DisGeNETCREB5
MedgenCREB5
Genetic Testing Registry CREB5
NextProtQ02930 [Medical]
GENETestsCREB5
Target ValidationCREB5
Huge Navigator CREB5 [HugePedia]
ClinGenCREB5
Clinical trials, drugs, therapy
MyCancerGenomeCREB5
Protein Interactions : CTDCREB5
Pharm GKB GenePA134930491
PharosQ02930
Clinical trialCREB5
Miscellaneous
canSAR (ICR)CREB5
HarmonizomeCREB5
ARCHS4CREB5
DataMed IndexCREB5
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCREB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:28:56 CET 2022

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