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CREB5 (cAMP responsive element binding protein 5)

Identity

Alias_symbol (synonym)H_GS165L15.1
CRE-BPA
Other aliasCREB-5
HGNC (Hugo) CREB5
LocusID (NCBI) 9586
Atlas_Id 54898
Location 7p15.1  [Link to chromosome band 7p15]
Location_base_pair Starts at 28685981 and ends at 28825894 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID5B (10q21.2) / CREB5 (7p15.1)CCND2 (12p13.32) / CREB5 (7p15.1)CREB5 (7p15.1) / CD74 (5q32)
CREB5 (7p15.1) / KCNH2 (7q36.1)CREB5 (7p15.1) / NUDCD2 (5q34)CREB5 (7p15.1) / USP42 (7p22.1)
ELF4 (Xq26.1) / CREB5 (7p15.1)FAM188B (7p14.3) / CREB5 (7p15.1)ZNF711 (Xq21.1) / CREB5 (7p15.1)
CREB5 7p15.1 / KCNH2 7q36.1CREB5 7p15.1 / USP42 7p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CREB5   16844
Cards
Entrez_Gene (NCBI)CREB5  9586  cAMP responsive element binding protein 5
AliasesCRE-BPA; CREB-5
GeneCards (Weizmann)CREB5
Ensembl hg19 (Hinxton)ENSG00000146592 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146592 [Gene_View]  chr7:28685981-28825894 [Contig_View]  CREB5 [Vega]
ICGC DataPortalENSG00000146592
TCGA cBioPortalCREB5
AceView (NCBI)CREB5
Genatlas (Paris)CREB5
WikiGenes9586
SOURCE (Princeton)CREB5
Genetics Home Reference (NIH)CREB5
Genomic and cartography
GoldenPath hg38 (UCSC)CREB5  -     chr7:28685981-28825894 +  7p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CREB5  -     7p15.1   [Description]    (hg19-Feb_2009)
EnsemblCREB5 - 7p15.1 [CytoView hg19]  CREB5 - 7p15.1 [CytoView hg38]
Mapping of homologs : NCBICREB5 [Mapview hg19]  CREB5 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB209262 AB451409 AK057151 AK292916 AK298121
RefSeq transcript (Entrez)NM_001011666 NM_004904 NM_182898 NM_182899
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CREB5
Cluster EST : UnigeneHs.437075 [ NCBI ]
CGAP (NCI)Hs.437075
Alternative Splicing GalleryENSG00000146592
Gene ExpressionCREB5 [ NCBI-GEO ]   CREB5 [ EBI - ARRAY_EXPRESS ]   CREB5 [ SEEK ]   CREB5 [ MEM ]
Gene Expression Viewer (FireBrowse)CREB5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9586
GTEX Portal (Tissue expression)CREB5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02930   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02930  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02930
Splice isoforms : SwissVarQ02930
PhosPhoSitePlusQ02930
Domaine pattern : Prosite (Expaxy)BZIP (PS50217)    BZIP_BASIC (PS00036)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)bZIP    TF_CRE-BP1-typ    Znf_C2H2    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)bZIP_1 (PF00170)   
Domain families : Pfam (NCBI)pfam00170   
Domain families : Smart (EMBL)BRLZ (SM00338)  
Conserved Domain (NCBI)CREB5
DMDM Disease mutations9586
Blocks (Seattle)CREB5
SuperfamilyQ02930
Human Protein AtlasENSG00000146592
Peptide AtlasQ02930
HPRD09896
IPIIPI00027461   IPI00478946   IPI00397362   IPI00410078   IPI00917385   IPI00916918   IPI01015865   
Protein Interaction databases
DIP (DOE-UCLA)Q02930
IntAct (EBI)Q02930
FunCoupENSG00000146592
BioGRIDCREB5
STRING (EMBL)CREB5
ZODIACCREB5
Ontologies - Pathways
QuickGOQ02930
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  metal ion binding  extracellular exosome  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  metal ion binding  extracellular exosome  
Pathways : KEGG   
NDEx NetworkCREB5
Atlas of Cancer Signalling NetworkCREB5
Wikipedia pathwaysCREB5
Orthology - Evolution
OrthoDB9586
GeneTree (enSembl)ENSG00000146592
Phylogenetic Trees/Animal Genes : TreeFamCREB5
HOVERGENQ02930
HOGENOMQ02930
Homologs : HomoloGeneCREB5
Homology/Alignments : Family Browser (UCSC)CREB5
Gene fusions - Rearrangements
Fusion : MitelmanCREB5/KCNH2 [7p15.1/7q36.1]  
Fusion : MitelmanCREB5/USP42 [7p15.1/7p22.1]  [t(7;7)(p15;p22)]  
Fusion: TCGACREB5 7p15.1 KCNH2 7q36.1 GBM
Fusion: TCGACREB5 7p15.1 USP42 7p22.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCREB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CREB5
dbVarCREB5
ClinVarCREB5
1000_GenomesCREB5 
Exome Variant ServerCREB5
ExAC (Exome Aggregation Consortium)CREB5 (select the gene name)
Genetic variants : HAPMAP9586
Genomic Variants (DGV)CREB5 [DGVbeta]
DECIPHERCREB5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCREB5 
Mutations
ICGC Data PortalCREB5 
TCGA Data PortalCREB5 
Broad Tumor PortalCREB5
OASIS PortalCREB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCREB5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCREB5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CREB5
DgiDB (Drug Gene Interaction Database)CREB5
DoCM (Curated mutations)CREB5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CREB5 (select a term)
intoGenCREB5
Cancer3DCREB5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCREB5
Genetic Testing Registry CREB5
NextProtQ02930 [Medical]
TSGene9586
GENETestsCREB5
Target ValidationCREB5
Huge Navigator CREB5 [HugePedia]
snp3D : Map Gene to Disease9586
BioCentury BCIQCREB5
ClinGenCREB5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9586
Chemical/Pharm GKB GenePA134930491
Clinical trialCREB5
Miscellaneous
canSAR (ICR)CREB5 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCREB5
EVEXCREB5
GoPubMedCREB5
iHOPCREB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:29:34 CEST 2017

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