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CRIPAK (cysteine-rich PAK1 inhibitor)

Identity

Alias_symbol (synonym)FLJ34443
Other alias-
HGNC (Hugo) CRIPAK
LocusID (NCBI) 285464
Atlas_Id 62087
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 1385340 and ends at 1389782 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DCN (12q21.33) / CRIPAK (4p16.3)UVSSA (4p16.3) / CRIPAK (4p16.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CRIPAK   26619
Cards
Entrez_Gene (NCBI)CRIPAK  285464  cysteine-rich PAK1 inhibitor
Aliases
GeneCards (Weizmann)CRIPAK
Ensembl hg19 (Hinxton)ENSG00000179979 [Gene_View]  chr4:1385340-1389782 [Contig_View]  CRIPAK [Vega]
Ensembl hg38 (Hinxton)ENSG00000179979 [Gene_View]  chr4:1385340-1389782 [Contig_View]  CRIPAK [Vega]
ICGC DataPortalENSG00000179979
TCGA cBioPortalCRIPAK
AceView (NCBI)CRIPAK
Genatlas (Paris)CRIPAK
WikiGenes285464
SOURCE (Princeton)CRIPAK
Genetics Home Reference (NIH)CRIPAK
Genomic and cartography
GoldenPath hg19 (UCSC)CRIPAK  -     chr4:1385340-1389782 +  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CRIPAK  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblCRIPAK - 4p16.3 [CytoView hg19]  CRIPAK - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBICRIPAK [Mapview hg19]  CRIPAK [Mapview hg38]
OMIM610203   
Gene and transcription
Genbank (Entrez)AA160784 AK091762 AK096209 AK126919 AK128809
RefSeq transcript (Entrez)NM_175918
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006051 NW_004929313
Consensus coding sequences : CCDS (NCBI)CRIPAK
Cluster EST : UnigeneHs.26410 [ NCBI ]
CGAP (NCI)Hs.26410
Alternative Splicing GalleryENSG00000179979
Gene ExpressionCRIPAK [ NCBI-GEO ]   CRIPAK [ EBI - ARRAY_EXPRESS ]   CRIPAK [ SEEK ]   CRIPAK [ MEM ]
Gene Expression Viewer (FireBrowse)CRIPAK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285464
GTEX Portal (Tissue expression)CRIPAK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1N5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1N5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1N5
Splice isoforms : SwissVarQ8N1N5
PhosPhoSitePlusQ8N1N5
Domains : Interpro (EBI)Post-SET_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)PostSET (SM00508)  
Conserved Domain (NCBI)CRIPAK
DMDM Disease mutations285464
Blocks (Seattle)CRIPAK
SuperfamilyQ8N1N5
Human Protein AtlasENSG00000179979
Peptide AtlasQ8N1N5
HPRD08753
IPIIPI00184021   IPI00443456   
Protein Interaction databases
DIP (DOE-UCLA)Q8N1N5
IntAct (EBI)Q8N1N5
FunCoupENSG00000179979
BioGRIDCRIPAK
STRING (EMBL)CRIPAK
ZODIACCRIPAK
Ontologies - Pathways
QuickGOQ8N1N5
Ontology : AmiGOprotein binding  nucleus  cytoplasm  endoplasmic reticulum  plasma membrane  negative regulation of protein kinase activity  negative regulation of intracellular estrogen receptor signaling pathway  response to estrogen  regulation of cytoskeleton organization  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  endoplasmic reticulum  plasma membrane  negative regulation of protein kinase activity  negative regulation of intracellular estrogen receptor signaling pathway  response to estrogen  regulation of cytoskeleton organization  
NDEx NetworkCRIPAK
Atlas of Cancer Signalling NetworkCRIPAK
Wikipedia pathwaysCRIPAK
Orthology - Evolution
OrthoDB285464
GeneTree (enSembl)ENSG00000179979
Phylogenetic Trees/Animal Genes : TreeFamCRIPAK
HOVERGENQ8N1N5
HOGENOMQ8N1N5
Homologs : HomoloGeneCRIPAK
Homology/Alignments : Family Browser (UCSC)CRIPAK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRIPAK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRIPAK
dbVarCRIPAK
ClinVarCRIPAK
1000_GenomesCRIPAK 
Exome Variant ServerCRIPAK
ExAC (Exome Aggregation Consortium)CRIPAK (select the gene name)
Genetic variants : HAPMAP285464
Genomic Variants (DGV)CRIPAK [DGVbeta]
DECIPHER (Syndromes)4:1385340-1389782  ENSG00000179979
CONAN: Copy Number AnalysisCRIPAK 
Mutations
ICGC Data PortalCRIPAK 
TCGA Data PortalCRIPAK 
Broad Tumor PortalCRIPAK
OASIS PortalCRIPAK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRIPAK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRIPAK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRIPAK
DgiDB (Drug Gene Interaction Database)CRIPAK
DoCM (Curated mutations)CRIPAK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRIPAK (select a term)
intoGenCRIPAK
Cancer3DCRIPAK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610203   
Orphanet
MedgenCRIPAK
Genetic Testing Registry CRIPAK
NextProtQ8N1N5 [Medical]
TSGene285464
GENETestsCRIPAK
Huge Navigator CRIPAK [HugePedia]
snp3D : Map Gene to Disease285464
BioCentury BCIQCRIPAK
ClinGenCRIPAK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285464
Chemical/Pharm GKB GenePA145149095
Clinical trialCRIPAK
Miscellaneous
canSAR (ICR)CRIPAK (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRIPAK
EVEXCRIPAK
GoPubMedCRIPAK
iHOPCRIPAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:00:20 CET 2017

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