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CRISP2 (cysteine rich secretory protein 2)

Identity

Alias_namesGAPDL5
TPX1
testis specific protein 1 (probe H4-1 p3-1)
Alias_symbol (synonym)CRISP-2
CT36
Other aliasTSP1
HGNC (Hugo) CRISP2
LocusID (NCBI) 7180
Atlas_Id 43097
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 49692358 and ends at 49713590 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CRISP2   12024
Cards
Entrez_Gene (NCBI)CRISP2  7180  cysteine rich secretory protein 2
AliasesCRISP-2; CT36; GAPDL5; TPX1; 
TSP1
GeneCards (Weizmann)CRISP2
Ensembl hg19 (Hinxton)ENSG00000124490 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124490 [Gene_View]  ENSG00000124490 [Sequence]  chr6:49692358-49713590 [Contig_View]  CRISP2 [Vega]
ICGC DataPortalENSG00000124490
TCGA cBioPortalCRISP2
AceView (NCBI)CRISP2
Genatlas (Paris)CRISP2
WikiGenes7180
SOURCE (Princeton)CRISP2
Genetics Home Reference (NIH)CRISP2
Genomic and cartography
GoldenPath hg38 (UCSC)CRISP2  -     chr6:49692358-49713590 -  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRISP2  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblCRISP2 - 6p12.3 [CytoView hg19]  CRISP2 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBICRISP2 [Mapview hg19]  CRISP2 [Mapview hg38]
OMIM187430   
Gene and transcription
Genbank (Entrez)AK128009 AK223337 AK292385 AY289796 AY292862
RefSeq transcript (Entrez)NM_001142407 NM_001142408 NM_001142417 NM_001142435 NM_001261822 NM_003296
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRISP2
Cluster EST : UnigeneHs.2042 [ NCBI ]
CGAP (NCI)Hs.2042
Alternative Splicing GalleryENSG00000124490
Gene ExpressionCRISP2 [ NCBI-GEO ]   CRISP2 [ EBI - ARRAY_EXPRESS ]   CRISP2 [ SEEK ]   CRISP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CRISP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7180
GTEX Portal (Tissue expression)CRISP2
Human Protein AtlasENSG00000124490-CRISP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16562   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16562  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16562
Splice isoforms : SwissVarP16562
PhosPhoSitePlusP16562
Domaine pattern : Prosite (Expaxy)CRISP_1 (PS01009)    CRISP_2 (PS01010)    SHKT (PS51670)   
Domains : Interpro (EBI)Allrgn_V5/Tpx1    Allrgn_V5/Tpx1_CS    CAP_domain    CAP_sf    Cysteine_rich_secretory    SCP_CRISP    ShKT_dom   
Domain families : Pfam (Sanger)CAP (PF00188)    Crisp (PF08562)   
Domain families : Pfam (NCBI)pfam00188    pfam08562   
Domain families : Smart (EMBL)SCP (SM00198)  
Conserved Domain (NCBI)CRISP2
DMDM Disease mutations7180
Blocks (Seattle)CRISP2
PDB (SRS)2CQ7   
PDB (PDBSum)2CQ7   
PDB (IMB)2CQ7   
PDB (RSDB)2CQ7   
Structural Biology KnowledgeBase2CQ7   
SCOP (Structural Classification of Proteins)2CQ7   
CATH (Classification of proteins structures)2CQ7   
SuperfamilyP16562
Human Protein Atlas [tissue]ENSG00000124490-CRISP2 [tissue]
Peptide AtlasP16562
HPRD01758
IPIIPI00029218   IPI00385520   
Protein Interaction databases
DIP (DOE-UCLA)P16562
IntAct (EBI)P16562
FunCoupENSG00000124490
BioGRIDCRISP2
STRING (EMBL)CRISP2
ZODIACCRISP2
Ontologies - Pathways
QuickGOP16562
Ontology : AmiGOextracellular space  
Ontology : EGO-EBIextracellular space  
NDEx NetworkCRISP2
Atlas of Cancer Signalling NetworkCRISP2
Wikipedia pathwaysCRISP2
Orthology - Evolution
OrthoDB7180
GeneTree (enSembl)ENSG00000124490
Phylogenetic Trees/Animal Genes : TreeFamCRISP2
HOVERGENP16562
HOGENOMP16562
Homologs : HomoloGeneCRISP2
Homology/Alignments : Family Browser (UCSC)CRISP2
Gene fusions - Rearrangements
Fusion : QuiverCRISP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRISP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRISP2
dbVarCRISP2
ClinVarCRISP2
1000_GenomesCRISP2 
Exome Variant ServerCRISP2
ExAC (Exome Aggregation Consortium)ENSG00000124490
GNOMAD BrowserENSG00000124490
Varsome BrowserCRISP2
Genetic variants : HAPMAP7180
Genomic Variants (DGV)CRISP2 [DGVbeta]
DECIPHERCRISP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRISP2 
Mutations
ICGC Data PortalCRISP2 
TCGA Data PortalCRISP2 
Broad Tumor PortalCRISP2
OASIS PortalCRISP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRISP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRISP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRISP2
DgiDB (Drug Gene Interaction Database)CRISP2
DoCM (Curated mutations)CRISP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRISP2 (select a term)
intoGenCRISP2
Cancer3DCRISP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM187430   
Orphanet
DisGeNETCRISP2
MedgenCRISP2
Genetic Testing Registry CRISP2
NextProtP16562 [Medical]
TSGene7180
GENETestsCRISP2
Target ValidationCRISP2
Huge Navigator CRISP2 [HugePedia]
snp3D : Map Gene to Disease7180
BioCentury BCIQCRISP2
ClinGenCRISP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7180
Chemical/Pharm GKB GenePA36703
Clinical trialCRISP2
Miscellaneous
canSAR (ICR)CRISP2 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRISP2
EVEXCRISP2
GoPubMedCRISP2
iHOPCRISP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:00:15 CET 2018

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