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CRISP3 (cysteine rich secretory protein 3)

Identity

Alias_symbol (synonym)SGP28
CRISP-3
CRS3
dJ442L6.3
Aeg2
Other alias
HGNC (Hugo) CRISP3
LocusID (NCBI) 10321
Atlas_Id 46180
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 49727381 and ends at 49744455 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
H6PD (1p36.22) / CRISP3 (6p12.3)H6PD 1p36.22 / CRISP3 6p12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;6)(p36;p12) H6PD/CRISP3


External links

Nomenclature
HGNC (Hugo)CRISP3   16904
Cards
Entrez_Gene (NCBI)CRISP3  10321  cysteine rich secretory protein 3
AliasesAeg2; CRISP-3; CRS3; SGP28; 
dJ442L6.3
GeneCards (Weizmann)CRISP3
Ensembl hg19 (Hinxton)ENSG00000096006 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000096006 [Gene_View]  ENSG00000096006 [Sequence]  chr6:49727381-49744455 [Contig_View]  CRISP3 [Vega]
ICGC DataPortalENSG00000096006
TCGA cBioPortalCRISP3
AceView (NCBI)CRISP3
Genatlas (Paris)CRISP3
WikiGenes10321
SOURCE (Princeton)CRISP3
Genetics Home Reference (NIH)CRISP3
Genomic and cartography
GoldenPath hg38 (UCSC)CRISP3  -     chr6:49727381-49744455 -  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRISP3  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblCRISP3 - 6p12.3 [CytoView hg19]  CRISP3 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBICRISP3 [Mapview hg19]  CRISP3 [Mapview hg38]
OMIM618062   
Gene and transcription
Genbank (Entrez)AK223380 AK292786 AK303966 AK313387 BC069580
RefSeq transcript (Entrez)NM_001190986 NM_006061
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRISP3
Cluster EST : UnigeneHs.404466 [ NCBI ]
CGAP (NCI)Hs.404466
Alternative Splicing GalleryENSG00000096006
Gene ExpressionCRISP3 [ NCBI-GEO ]   CRISP3 [ EBI - ARRAY_EXPRESS ]   CRISP3 [ SEEK ]   CRISP3 [ MEM ]
Gene Expression Viewer (FireBrowse)CRISP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10321
GTEX Portal (Tissue expression)CRISP3
Human Protein AtlasENSG00000096006-CRISP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54108   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54108  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54108
Splice isoforms : SwissVarP54108
PhosPhoSitePlusP54108
Domaine pattern : Prosite (Expaxy)CRISP_1 (PS01009)    CRISP_2 (PS01010)    SHKT (PS51670)   
Domains : Interpro (EBI)Allrgn_V5/Tpx1    Allrgn_V5/Tpx1_CS    CAP_domain    CAP_sf    Cysteine_rich_secretory    SCP_CRISP    ShKT_dom   
Domain families : Pfam (Sanger)CAP (PF00188)    Crisp (PF08562)   
Domain families : Pfam (NCBI)pfam00188    pfam08562   
Domain families : Smart (EMBL)SCP (SM00198)  
Conserved Domain (NCBI)CRISP3
DMDM Disease mutations10321
Blocks (Seattle)CRISP3
SuperfamilyP54108
Human Protein Atlas [tissue]ENSG00000096006-CRISP3 [tissue]
Peptide AtlasP54108
HPRD11788
IPIIPI01014029   IPI00942117   IPI00974055   IPI00974112   
Protein Interaction databases
DIP (DOE-UCLA)P54108
IntAct (EBI)P54108
FunCoupENSG00000096006
BioGRIDCRISP3
STRING (EMBL)CRISP3
ZODIACCRISP3
Ontologies - Pathways
QuickGOP54108
Ontology : AmiGOmolecular_function  extracellular region  extracellular region  extracellular space  extracellular space  defense response  extracellular matrix  specific granule lumen  specific granule  neutrophil degranulation  innate immune response  tertiary granule lumen  
Ontology : EGO-EBImolecular_function  extracellular region  extracellular region  extracellular space  extracellular space  defense response  extracellular matrix  specific granule lumen  specific granule  neutrophil degranulation  innate immune response  tertiary granule lumen  
NDEx NetworkCRISP3
Atlas of Cancer Signalling NetworkCRISP3
Wikipedia pathwaysCRISP3
Orthology - Evolution
OrthoDB10321
GeneTree (enSembl)ENSG00000096006
Phylogenetic Trees/Animal Genes : TreeFamCRISP3
HOVERGENP54108
HOGENOMP54108
Homologs : HomoloGeneCRISP3
Homology/Alignments : Family Browser (UCSC)CRISP3
Gene fusions - Rearrangements
Fusion : MitelmanH6PD/CRISP3 [1p36.22/6p12.3]  [t(1;6)(p36;p12)]  
Fusion PortalH6PD 1p36.22 CRISP3 6p12.3 PRAD
Fusion : QuiverCRISP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRISP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRISP3
dbVarCRISP3
ClinVarCRISP3
1000_GenomesCRISP3 
Exome Variant ServerCRISP3
ExAC (Exome Aggregation Consortium)ENSG00000096006
GNOMAD BrowserENSG00000096006
Varsome BrowserCRISP3
Genetic variants : HAPMAP10321
Genomic Variants (DGV)CRISP3 [DGVbeta]
DECIPHERCRISP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRISP3 
Mutations
ICGC Data PortalCRISP3 
TCGA Data PortalCRISP3 
Broad Tumor PortalCRISP3
OASIS PortalCRISP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRISP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRISP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRISP3
DgiDB (Drug Gene Interaction Database)CRISP3
DoCM (Curated mutations)CRISP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRISP3 (select a term)
intoGenCRISP3
Cancer3DCRISP3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618062   
Orphanet
DisGeNETCRISP3
MedgenCRISP3
Genetic Testing Registry CRISP3
NextProtP54108 [Medical]
TSGene10321
GENETestsCRISP3
Target ValidationCRISP3
Huge Navigator CRISP3 [HugePedia]
snp3D : Map Gene to Disease10321
BioCentury BCIQCRISP3
ClinGenCRISP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10321
Chemical/Pharm GKB GenePA134880440
Clinical trialCRISP3
Miscellaneous
canSAR (ICR)CRISP3 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRISP3
EVEXCRISP3
GoPubMedCRISP3
iHOPCRISP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:00:15 CET 2018

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