Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CROCC (ciliary rootlet coiled-coil, rootletin)

Identity

Alias_namesciliary rootlet protein
Alias_symbol (synonym)rootletin
ROLT
Other aliasTAX1BP2
HGNC (Hugo) CROCC
LocusID (NCBI) 9696
Atlas_Id 56628
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 16921950 and ends at 16972979 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CROCC (1p36.13) / FAM60A (12p11.21)CROCC (1p36.13) / PSG3 (19q13.2)TMSB4X (Xp22.2) / CROCC (1p36.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CROCC   21299
Cards
Entrez_Gene (NCBI)CROCC  9696  ciliary rootlet coiled-coil, rootletin
AliasesROLT; TAX1BP2
GeneCards (Weizmann)CROCC
Ensembl hg19 (Hinxton)ENSG00000058453 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058453 [Gene_View]  chr1:16921950-16972979 [Contig_View]  CROCC [Vega]
ICGC DataPortalENSG00000058453
TCGA cBioPortalCROCC
AceView (NCBI)CROCC
Genatlas (Paris)CROCC
WikiGenes9696
SOURCE (Princeton)CROCC
Genetics Home Reference (NIH)CROCC
Genomic and cartography
GoldenPath hg38 (UCSC)CROCC  -     chr1:16921950-16972979 +  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CROCC  -     1p36.13   [Description]    (hg19-Feb_2009)
EnsemblCROCC - 1p36.13 [CytoView hg19]  CROCC - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBICROCC [Mapview hg19]  CROCC [Mapview hg38]
OMIM615776   
Gene and transcription
Genbank (Entrez)AB007914 AF527734 AK026910 BC126911 BC126912
RefSeq transcript (Entrez)NM_014675
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CROCC
Cluster EST : UnigeneHs.309403 [ NCBI ]
CGAP (NCI)Hs.309403
Alternative Splicing GalleryENSG00000058453
Gene ExpressionCROCC [ NCBI-GEO ]   CROCC [ EBI - ARRAY_EXPRESS ]   CROCC [ SEEK ]   CROCC [ MEM ]
Gene Expression Viewer (FireBrowse)CROCC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9696
GTEX Portal (Tissue expression)CROCC
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TZA2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TZA2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TZA2
Splice isoforms : SwissVarQ5TZA2
PhosPhoSitePlusQ5TZA2
Domains : Interpro (EBI)Rootletin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CROCC
DMDM Disease mutations9696
Blocks (Seattle)CROCC
SuperfamilyQ5TZA2
Human Protein AtlasENSG00000058453
Peptide AtlasQ5TZA2
HPRD16758
IPIIPI00456492   IPI00644892   
Protein Interaction databases
DIP (DOE-UCLA)Q5TZA2
IntAct (EBI)Q5TZA2
FunCoupENSG00000058453
BioGRIDCROCC
STRING (EMBL)CROCC
ZODIACCROCC
Ontologies - Pathways
QuickGOQ5TZA2
Ontology : AmiGOphotoreceptor inner segment  actin binding  structural molecule activity  protein binding  centrosome  centriole  centriole  cytosol  plasma membrane  centrosome cycle  protein localization  centriole-centriole cohesion  epithelial structure maintenance  actin cytoskeleton  kinesin binding  ciliary basal body organization  protein localization to organelle  ciliary rootlet  photoreceptor cell maintenance  positive regulation of cilium assembly  establishment of organelle localization  extracellular exosome  positive regulation of protein localization to cilium  
Ontology : EGO-EBIphotoreceptor inner segment  actin binding  structural molecule activity  protein binding  centrosome  centriole  centriole  cytosol  plasma membrane  centrosome cycle  protein localization  centriole-centriole cohesion  epithelial structure maintenance  actin cytoskeleton  kinesin binding  ciliary basal body organization  protein localization to organelle  ciliary rootlet  photoreceptor cell maintenance  positive regulation of cilium assembly  establishment of organelle localization  extracellular exosome  positive regulation of protein localization to cilium  
NDEx NetworkCROCC
Atlas of Cancer Signalling NetworkCROCC
Wikipedia pathwaysCROCC
Orthology - Evolution
OrthoDB9696
GeneTree (enSembl)ENSG00000058453
Phylogenetic Trees/Animal Genes : TreeFamCROCC
HOVERGENQ5TZA2
HOGENOMQ5TZA2
Homologs : HomoloGeneCROCC
Homology/Alignments : Family Browser (UCSC)CROCC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCROCC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CROCC
dbVarCROCC
ClinVarCROCC
1000_GenomesCROCC 
Exome Variant ServerCROCC
ExAC (Exome Aggregation Consortium)CROCC (select the gene name)
Genetic variants : HAPMAP9696
Genomic Variants (DGV)CROCC [DGVbeta]
DECIPHERCROCC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCROCC 
Mutations
ICGC Data PortalCROCC 
TCGA Data PortalCROCC 
Broad Tumor PortalCROCC
OASIS PortalCROCC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCROCC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCROCC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CROCC
DgiDB (Drug Gene Interaction Database)CROCC
DoCM (Curated mutations)CROCC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CROCC (select a term)
intoGenCROCC
Cancer3DCROCC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615776   
Orphanet
MedgenCROCC
Genetic Testing Registry CROCC
NextProtQ5TZA2 [Medical]
TSGene9696
GENETestsCROCC
Target ValidationCROCC
Huge Navigator CROCC [HugePedia]
snp3D : Map Gene to Disease9696
BioCentury BCIQCROCC
ClinGenCROCC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9696
Chemical/Pharm GKB GenePA134911945
Clinical trialCROCC
Miscellaneous
canSAR (ICR)CROCC (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCROCC
EVEXCROCC
GoPubMedCROCC
iHOPCROCC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:29:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.