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CRTC3 (CREB regulated transcription coactivator 3)

Identity

Other namesTORC-3
TORC3
HGNC (Hugo) CRTC3
LocusID (NCBI) 64784
Atlas_Id 50126
Location 15q26.1
Location_base_pair Starts at 91073118 and ends at 91188577 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CRTC3   26148
Cards
Entrez_Gene (NCBI)CRTC3  64784  CREB regulated transcription coactivator 3
GeneCards (Weizmann)CRTC3
Ensembl hg19 (Hinxton)ENSG00000140577 [Gene_View]  chr15:91073118-91188577 [Contig_View]  CRTC3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000140577 [Gene_View]  chr15:91073118-91188577 [Contig_View]  CRTC3 [Vega]
ICGC DataPortalENSG00000140577
TCGA cBioPortalCRTC3
AceView (NCBI)CRTC3
Genatlas (Paris)CRTC3
WikiGenes64784
SOURCE (Princeton)CRTC3
Genomic and cartography
GoldenPath hg19 (UCSC)CRTC3  -     chr15:91073118-91188577 +  15q26.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CRTC3  -     15q26.1   [Description]    (hg38-Dec_2013)
EnsemblCRTC3 - 15q26.1 [CytoView hg19]  CRTC3 - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBICRTC3 [Mapview hg19]  CRTC3 [Mapview hg38]
OMIM608986   
Gene and transcription
Genbank (Entrez)AI969212 AK025521 AK074170 AK090443 AK225300
RefSeq transcript (Entrez)NM_001042574 NM_022769
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929399
Consensus coding sequences : CCDS (NCBI)CRTC3
Cluster EST : UnigeneHs.567572 [ NCBI ]
CGAP (NCI)Hs.567572
Alternative Splicing : Fast-db (Paris)GSHG0010153
Alternative Splicing GalleryENSG00000140577
Gene ExpressionCRTC3 [ NCBI-GEO ]     CRTC3 [ SEEK ]   CRTC3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UUV7 (Uniprot)
NextProtQ6UUV7  [Medical]
With graphics : InterProQ6UUV7
Splice isoforms : SwissVarQ6UUV7 (Swissvar)
Domains : Interpro (EBI)TORC    TORC_C    TORC_M    TORC_N   
Related proteins : CluSTrQ6UUV7
Domain families : Pfam (Sanger)TORC_C (PF12886)    TORC_M (PF12885)    TORC_N (PF12884)   
Domain families : Pfam (NCBI)pfam12886    pfam12885    pfam12884   
DMDM Disease mutations64784
Blocks (Seattle)Q6UUV7
Human Protein AtlasENSG00000140577
Peptide AtlasQ6UUV7
HPRD13384
IPIIPI00783045   IPI00784401   IPI00885192   
Protein Interaction databases
DIP (DOE-UCLA)Q6UUV7
IntAct (EBI)Q6UUV7
FunCoupENSG00000140577
BioGRIDCRTC3
IntegromeDBCRTC3
STRING (EMBL)CRTC3
Ontologies - Pathways
QuickGOQ6UUV7
Ontology : AmiGOnucleoplasm  cytoplasm  transcription, DNA-templated  cAMP response element binding protein binding  viral process  positive regulation of CREB transcription factor activity  macrophage activation  negative regulation of cAMP-mediated signaling  positive regulation of transcription from RNA polymerase II promoter  negative regulation of lipid catabolic process  protein homotetramerization  energy homeostasis  
Ontology : EGO-EBInucleoplasm  cytoplasm  transcription, DNA-templated  cAMP response element binding protein binding  viral process  positive regulation of CREB transcription factor activity  macrophage activation  negative regulation of cAMP-mediated signaling  positive regulation of transcription from RNA polymerase II promoter  negative regulation of lipid catabolic process  protein homotetramerization  energy homeostasis  
Pathways : KEGGHTLV-I infection   
Protein Interaction DatabaseCRTC3
DoCM (Curated mutations)CRTC3
Wikipedia pathwaysCRTC3
Gene fusion - Rearrangements
Rearrangement : COSMICCRTC3 [15q26.1]  -  MAML2 [11q21]  [fusion_1104]  [fusion_1105]
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerCRTC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRTC3
dbVarCRTC3
ClinVarCRTC3
1000_GenomesCRTC3 
Exome Variant ServerCRTC3
SNP (GeneSNP Utah)CRTC3
SNP : HGBaseCRTC3
Genetic variants : HAPMAPCRTC3
Genomic Variants (DGV)CRTC3 [DGVbeta]
Mutations
ICGC Data PortalCRTC3 
TCGA Data PortalCRTC3 
Tumor PortalCRTC3
Cancer Gene: CensusCRTC3 
Somatic Mutations in Cancer : COSMICCRTC3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)15:91073118-91188577
CONAN: Copy Number AnalysisCRTC3 
Mutations and Diseases : HGMDCRTC3
OMIM608986   
MedgenCRTC3
NextProtQ6UUV7 [Medical]
GENETestsCRTC3
Disease Genetic AssociationCRTC3
Huge Navigator CRTC3 [HugePedia]  CRTC3 [HugeCancerGEM]
snp3D : Map Gene to Disease64784
DGIdb (Drug Gene Interaction db)CRTC3
General knowledge
Homologs : HomoloGeneCRTC3
Homology/Alignments : Family Browser (UCSC)CRTC3
Phylogenetic Trees/Animal Genes : TreeFamCRTC3
Chemical/Protein Interactions : CTD64784
Chemical/Pharm GKB GenePA142672074
Clinical trialCRTC3
Cancer Resource (Charite)ENSG00000140577
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
CoreMineCRTC3
GoPubMedCRTC3
iHOPCRTC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:04:53 CEST 2015

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