Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CRX (cone-rod homeobox)

Identity

Other namesCORD2
CRD
LCA7
OTX3
HGNC (Hugo) CRX
LocusID (NCBI) 1406
Location 19q13.33
Location_base_pair Starts at 48325099 and ends at 48346586 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)CRX   2383
Cards
Entrez_Gene (NCBI)CRX  1406  cone-rod homeobox
GeneCards (Weizmann)CRX
Ensembl (Hinxton)ENSG00000105392 [Gene_View]  chr19:48325099-48346586 [Contig_View]  CRX [Vega]
ICGC DataPortalENSG00000105392
cBioPortalCRX
AceView (NCBI)CRX
Genatlas (Paris)CRX
WikiGenes1406
SOURCE (Princeton)NM_000554
Genomic and cartography
GoldenPath (UCSC)CRX  -  19q13.33   chr19:48325099-48346586 +  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblCRX - 19q13.33 [CytoView]
Mapping of homologs : NCBICRX [Mapview]
OMIM120970   268000   602225   613829   
Gene and transcription
Genbank (Entrez)AF335247 AF335249 AF335593 AF335594 AF335595
RefSeq transcript (Entrez)NM_000554
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_008605 NT_011109 NW_001838496 NW_004929415
Consensus coding sequences : CCDS (NCBI)CRX
Cluster EST : UnigeneHs.639114 [ NCBI ]
CGAP (NCI)Hs.639114
Alternative Splicing : Fast-db (Paris)GSHG0015060
Alternative Splicing GalleryENSG00000105392
Gene ExpressionCRX [ NCBI-GEO ]     CRX [ SEEK ]   CRX [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43186 (Uniprot)
NextProtO43186  [Medical]
With graphics : InterProO43186
Splice isoforms : SwissVarO43186 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS [organisation]   Homeobox_dom [organisation]   Homeodomain-like [organisation]   Otx_TF_C [organisation]  
Related proteins : CluSTrO43186
Domain families : Pfam (Sanger)Homeobox (PF00046)    TF_Otx (PF03529)   
Domain families : Pfam (NCBI)pfam00046    pfam03529   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations1406
Blocks (Seattle)O43186
Human Protein AtlasENSG00000105392 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO43186
HPRD03748
IPIIPI00011226   IPI00954900   IPI00977106   
Protein Interaction databases
DIP (DOE-UCLA)O43186
IntAct (EBI)O43186
FunCoupENSG00000105392
BioGRIDCRX
InParanoidO43186
Interologous Interaction database O43186
IntegromeDBCRX
STRING (EMBL)CRX
Ontologies - Pathways
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  chromatin binding  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  transcription, DNA-templated  regulation of transcription, DNA-templated  visual perception  circadian rhythm  organ morphogenesis  nuclear hormone receptor binding  leucine zipper domain binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of photoreceptor cell differentiation  response to stimulus  retina development in camera-type eye  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  chromatin binding  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  transcription, DNA-templated  regulation of transcription, DNA-templated  visual perception  circadian rhythm  organ morphogenesis  nuclear hormone receptor binding  leucine zipper domain binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of photoreceptor cell differentiation  response to stimulus  retina development in camera-type eye  
Protein Interaction DatabaseCRX
Wikipedia pathwaysCRX
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CRX
snp3D : Map Gene to Disease1406
SNP (GeneSNP Utah)CRX
SNP : HGBaseCRX
Genetic variants : HAPMAPCRX
Exome VariantCRX
1000_GenomesCRX 
ICGC programENSG00000105392 
Somatic Mutations in Cancer : COSMICCRX 
CONAN: Copy Number AnalysisCRX 
Mutations and Diseases : HGMDCRX
Mutations and Diseases : intOGenCRX
Genomic VariantsCRX  CRX [DGVbeta]
dbVarCRX
ClinVarCRX
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM120970    268000    602225    613829   
MedgenCRX
GENETestsCRX
Disease Genetic AssociationCRX
Huge Navigator CRX [HugePedia]  CRX [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCRX
Homology/Alignments : Family Browser (UCSC)CRX
Phylogenetic Trees/Animal Genes : TreeFamCRX
Chemical/Protein Interactions : CTD1406
Chemical/Pharm GKB GenePA26903
Clinical trialCRX
Cancer Resource (Charite)ENSG00000105392
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
CoreMineCRX
iHOPCRX
OncoSearchCRX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:43:14 CEST 2014

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