Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1409
MIM: 123580
HGNC: 2388
Ensembl: ENSG00000160202
Variants:
dbSNP: 1409
ClinVar: 1409
TCGA: ENSG00000160202
COSMIC: CRYAA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160202 | ENST00000291554 | P02489 |
| ENSG00000160202 | ENST00000398133 | E7EWH7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36380611 | 2023 | Association between single nucleotide polymorphisms in exon 3 of the alpha-A-crystallin gene and susceptibility to age-related cataract. | 1 |
| 37253645 | 2023 | Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells. | 0 |
| 37807341 | 2023 | Mutational analysis of CRYAA gene of cataract and investigating risk assessment factors responsible for eye diseases in district buner, KPK, Pakistan. | 0 |
| 36380611 | 2023 | Association between single nucleotide polymorphisms in exon 3 of the alpha-A-crystallin gene and susceptibility to age-related cataract. | 1 |
| 37253645 | 2023 | Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells. | 0 |
| 37807341 | 2023 | Mutational analysis of CRYAA gene of cataract and investigating risk assessment factors responsible for eye diseases in district buner, KPK, Pakistan. | 0 |
| 36338667 | 2022 | Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells. | 2 |
| 36338667 | 2022 | Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells. | 2 |
| 33444727 | 2021 | Nucleosomal association and altered interactome underlie the mechanism of cataract caused by the R54C mutation of αA-crystallin. | 3 |
| 33626371 | 2021 | Amyloid cross-sequence interaction between Aβ(1-40) and αA(66-80) in relation to the pathogenesis of cataract. | 0 |
| 34096886 | 2021 | Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin. | 1 |
| 33444727 | 2021 | Nucleosomal association and altered interactome underlie the mechanism of cataract caused by the R54C mutation of αA-crystallin. | 3 |
| 33626371 | 2021 | Amyloid cross-sequence interaction between Aβ(1-40) and αA(66-80) in relation to the pathogenesis of cataract. | 0 |
| 34096886 | 2021 | Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin. | 1 |
| 32184356 | 2020 | Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of α-crystallin: Implications for lens aging and presbyopia. | 19 |
Citation
Dessen P
CRYAA (crystallin alpha A)
Atlas Genet Cytogenet Oncol Haematol. 2010-08-01
Online version: http://atlasgeneticsoncology.org/gene/51650/cryaa
