Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CRYBA4 (crystallin beta A4)

Identity

Alias_namescrystallin, beta A4
Other aliasCTRCT23
CYRBA4
MCOPCT4
HGNC (Hugo) CRYBA4
LocusID (NCBI) 1413
Atlas_Id 62103
Location 22q12.1  [Link to chromosome band 22q12]
Location_base_pair Starts at 26621964 and ends at 26630672 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
USP32 (17q23.1) / CRYBA4 (22q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CRYBA4   2396
Cards
Entrez_Gene (NCBI)CRYBA4  1413  crystallin beta A4
AliasesCTRCT23; CYRBA4; MCOPCT4
GeneCards (Weizmann)CRYBA4
Ensembl hg19 (Hinxton)ENSG00000196431 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196431 [Gene_View]  chr22:26621964-26630672 [Contig_View]  CRYBA4 [Vega]
ICGC DataPortalENSG00000196431
TCGA cBioPortalCRYBA4
AceView (NCBI)CRYBA4
Genatlas (Paris)CRYBA4
WikiGenes1413
SOURCE (Princeton)CRYBA4
Genetics Home Reference (NIH)CRYBA4
Genomic and cartography
GoldenPath hg38 (UCSC)CRYBA4  -     chr22:26621964-26630672 +  22q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRYBA4  -     22q12.1   [Description]    (hg19-Feb_2009)
EnsemblCRYBA4 - 22q12.1 [CytoView hg19]  CRYBA4 - 22q12.1 [CytoView hg38]
Mapping of homologs : NCBICRYBA4 [Mapview hg19]  CRYBA4 [Mapview hg38]
OMIM123631   610425   
Gene and transcription
Genbank (Entrez)BC069404 BC096171 BC096172 BC096173 BC096174
RefSeq transcript (Entrez)NM_001886
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRYBA4
Cluster EST : UnigeneHs.57690 [ NCBI ]
CGAP (NCI)Hs.57690
Alternative Splicing GalleryENSG00000196431
Gene ExpressionCRYBA4 [ NCBI-GEO ]   CRYBA4 [ EBI - ARRAY_EXPRESS ]   CRYBA4 [ SEEK ]   CRYBA4 [ MEM ]
Gene Expression Viewer (FireBrowse)CRYBA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1413
GTEX Portal (Tissue expression)CRYBA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53673   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53673  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53673
Splice isoforms : SwissVarP53673
PhosPhoSitePlusP53673
Domaine pattern : Prosite (Expaxy)CRYSTALLIN_BETA_GAMMA (PS50915)   
Domains : Interpro (EBI)Beta/gamma_crystallin    CRYBA4    G_crystallin-rel   
Domain families : Pfam (Sanger)Crystall (PF00030)   
Domain families : Pfam (NCBI)pfam00030   
Domain families : Smart (EMBL)XTALbg (SM00247)  
Conserved Domain (NCBI)CRYBA4
DMDM Disease mutations1413
Blocks (Seattle)CRYBA4
PDB (SRS)3LWK   
PDB (PDBSum)3LWK   
PDB (IMB)3LWK   
PDB (RSDB)3LWK   
Structural Biology KnowledgeBase3LWK   
SCOP (Structural Classification of Proteins)3LWK   
CATH (Classification of proteins structures)3LWK   
SuperfamilyP53673
Human Protein AtlasENSG00000196431
Peptide AtlasP53673
HPRD00432
IPIIPI00878361   
Protein Interaction databases
DIP (DOE-UCLA)P53673
IntAct (EBI)P53673
FunCoupENSG00000196431
BioGRIDCRYBA4
STRING (EMBL)CRYBA4
ZODIACCRYBA4
Ontologies - Pathways
QuickGOP53673
Ontology : AmiGOmolecular_function  structural constituent of eye lens  protein binding  cellular_component  visual perception  visual perception  camera-type eye development  
Ontology : EGO-EBImolecular_function  structural constituent of eye lens  protein binding  cellular_component  visual perception  visual perception  camera-type eye development  
NDEx NetworkCRYBA4
Atlas of Cancer Signalling NetworkCRYBA4
Wikipedia pathwaysCRYBA4
Orthology - Evolution
OrthoDB1413
GeneTree (enSembl)ENSG00000196431
Phylogenetic Trees/Animal Genes : TreeFamCRYBA4
HOVERGENP53673
HOGENOMP53673
Homologs : HomoloGeneCRYBA4
Homology/Alignments : Family Browser (UCSC)CRYBA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRYBA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRYBA4
dbVarCRYBA4
ClinVarCRYBA4
1000_GenomesCRYBA4 
Exome Variant ServerCRYBA4
ExAC (Exome Aggregation Consortium)CRYBA4 (select the gene name)
Genetic variants : HAPMAP1413
Genomic Variants (DGV)CRYBA4 [DGVbeta]
DECIPHERCRYBA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRYBA4 
Mutations
ICGC Data PortalCRYBA4 
TCGA Data PortalCRYBA4 
Broad Tumor PortalCRYBA4
OASIS PortalCRYBA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRYBA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRYBA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch CRYBA4
DgiDB (Drug Gene Interaction Database)CRYBA4
DoCM (Curated mutations)CRYBA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRYBA4 (select a term)
intoGenCRYBA4
Cancer3DCRYBA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123631    610425   
Orphanet1584    23423   
MedgenCRYBA4
Genetic Testing Registry CRYBA4
NextProtP53673 [Medical]
TSGene1413
GENETestsCRYBA4
Target ValidationCRYBA4
Huge Navigator CRYBA4 [HugePedia]
snp3D : Map Gene to Disease1413
BioCentury BCIQCRYBA4
ClinGenCRYBA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1413
Chemical/Pharm GKB GenePA26910
Clinical trialCRYBA4
Miscellaneous
canSAR (ICR)CRYBA4 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRYBA4
EVEXCRYBA4
GoPubMedCRYBA4
iHOPCRYBA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:44:36 CEST 2017

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