Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CRYZ (crystallin zeta)

Identity

Alias_namescrystallin
Other alias-
HGNC (Hugo) CRYZ
LocusID (NCBI) 1429
Atlas_Id 51607
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 74705488 and ends at 74733408 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MGST1 (12p12.3) / CRYZ (1p31.1)SPATA6 (1p33) / CRYZ (1p31.1)SPATA6 1p33 / CRYZ 1p31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CRYZ   2419
Cards
Entrez_Gene (NCBI)CRYZ  1429  crystallin zeta
Aliases
GeneCards (Weizmann)CRYZ
Ensembl hg19 (Hinxton)ENSG00000116791 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116791 [Gene_View]  chr1:74705488-74733408 [Contig_View]  CRYZ [Vega]
ICGC DataPortalENSG00000116791
TCGA cBioPortalCRYZ
AceView (NCBI)CRYZ
Genatlas (Paris)CRYZ
WikiGenes1429
SOURCE (Princeton)CRYZ
Genetics Home Reference (NIH)CRYZ
Genomic and cartography
GoldenPath hg38 (UCSC)CRYZ  -     chr1:74705488-74733408 -  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRYZ  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblCRYZ - 1p31.1 [CytoView hg19]  CRYZ - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBICRYZ [Mapview hg19]  CRYZ [Mapview hg38]
OMIM123691   
Gene and transcription
Genbank (Entrez)AB209714 AK123469 AK128794 AK223150 AK223201
RefSeq transcript (Entrez)NM_001130042 NM_001130043 NM_001134759 NM_001889
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRYZ
Cluster EST : UnigeneHs.83114 [ NCBI ]
CGAP (NCI)Hs.83114
Alternative Splicing GalleryENSG00000116791
Gene ExpressionCRYZ [ NCBI-GEO ]   CRYZ [ EBI - ARRAY_EXPRESS ]   CRYZ [ SEEK ]   CRYZ [ MEM ]
Gene Expression Viewer (FireBrowse)CRYZ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1429
GTEX Portal (Tissue expression)CRYZ
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08257   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08257  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08257
Splice isoforms : SwissVarQ08257
Catalytic activity : Enzyme1.6.5.5 [ Enzyme-Expasy ]   1.6.5.51.6.5.5 [ IntEnz-EBI ]   1.6.5.5 [ BRENDA ]   1.6.5.5 [ KEGG ]   
PhosPhoSitePlusQ08257
Domaine pattern : Prosite (Expaxy)QOR_ZETA_CRYSTAL (PS01162)   
Domains : Interpro (EBI)ADH_C    ADH_N    GroES-like    NAD(P)-bd_dom    PKS_ER    Quin_OxRdtase/zeta-crystal_CS   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
Domain families : Smart (EMBL)PKS_ER (SM00829)  
Conserved Domain (NCBI)CRYZ
DMDM Disease mutations1429
Blocks (Seattle)CRYZ
PDB (SRS)1YB5   
PDB (PDBSum)1YB5   
PDB (IMB)1YB5   
PDB (RSDB)1YB5   
Structural Biology KnowledgeBase1YB5   
SCOP (Structural Classification of Proteins)1YB5   
CATH (Classification of proteins structures)1YB5   
SuperfamilyQ08257
Human Protein AtlasENSG00000116791
Peptide AtlasQ08257
HPRD00437
IPIIPI00000792   IPI00645425   IPI00641565   IPI00642016   IPI00647366   
Protein Interaction databases
DIP (DOE-UCLA)Q08257
IntAct (EBI)Q08257
FunCoupENSG00000116791
BioGRIDCRYZ
STRING (EMBL)CRYZ
ZODIACCRYZ
Ontologies - Pathways
QuickGOQ08257
Ontology : AmiGOmRNA 3'-UTR binding  NADPH:quinone reductase activity  cytosol  visual perception  zinc ion binding  xenobiotic catabolic process  protein homotetramerization  oxidation-reduction process  extracellular exosome  NADPH binding  NADH binding  
Ontology : EGO-EBImRNA 3'-UTR binding  NADPH:quinone reductase activity  cytosol  visual perception  zinc ion binding  xenobiotic catabolic process  protein homotetramerization  oxidation-reduction process  extracellular exosome  NADPH binding  NADH binding  
Pathways : BIOCARTAOxidative Stress Induced Gene Expression Via Nrf2 [Genes]   
NDEx NetworkCRYZ
Atlas of Cancer Signalling NetworkCRYZ
Wikipedia pathwaysCRYZ
Orthology - Evolution
OrthoDB1429
GeneTree (enSembl)ENSG00000116791
Phylogenetic Trees/Animal Genes : TreeFamCRYZ
HOVERGENQ08257
HOGENOMQ08257
Homologs : HomoloGeneCRYZ
Homology/Alignments : Family Browser (UCSC)CRYZ
Gene fusions - Rearrangements
Fusion : MitelmanSPATA6/CRYZ [1p33/1p31.1]  [t(1;1)(p31;p33)]  
Fusion: TCGASPATA6 1p33 CRYZ 1p31.1 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRYZ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRYZ
dbVarCRYZ
ClinVarCRYZ
1000_GenomesCRYZ 
Exome Variant ServerCRYZ
ExAC (Exome Aggregation Consortium)CRYZ (select the gene name)
Genetic variants : HAPMAP1429
Genomic Variants (DGV)CRYZ [DGVbeta]
DECIPHERCRYZ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRYZ 
Mutations
ICGC Data PortalCRYZ 
TCGA Data PortalCRYZ 
Broad Tumor PortalCRYZ
OASIS PortalCRYZ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRYZ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRYZ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRYZ
DgiDB (Drug Gene Interaction Database)CRYZ
DoCM (Curated mutations)CRYZ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRYZ (select a term)
intoGenCRYZ
Cancer3DCRYZ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123691   
Orphanet
MedgenCRYZ
Genetic Testing Registry CRYZ
NextProtQ08257 [Medical]
TSGene1429
GENETestsCRYZ
Target ValidationCRYZ
Huge Navigator CRYZ [HugePedia]
snp3D : Map Gene to Disease1429
BioCentury BCIQCRYZ
ClinGenCRYZ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1429
Chemical/Pharm GKB GenePA26925
Clinical trialCRYZ
Miscellaneous
canSAR (ICR)CRYZ (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRYZ
EVEXCRYZ
GoPubMedCRYZ
iHOPCRYZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:58:41 CEST 2017

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