Identity
HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
CD131,CDw131,IL3RB,IL5RB,SMDP5,betaGMR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1439
MIM: 138981
HGNC: 2436
Ensembl: ENSG00000100368
Variants:
dbSNP: 1439
ClinVar: 1439
TCGA: ENSG00000100368
COSMIC: CSF2RB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100368 | ENST00000262825 | Q6NSJ8 |
| ENSG00000100368 | ENST00000403662 | P32927 |
| ENSG00000100368 | ENST00000406230 | P32927 |
| ENSG00000100368 | ENST00000421539 | B0QY07 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34750506 | 2022 | The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML. | 9 |
| 34750506 | 2022 | The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML. | 9 |
| 33589587 | 2021 | Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis. | 17 |
| 33784678 | 2021 | The Truncated Splice Variant of the Granulocyte-Macrophage-Colony-Stimulating Factor Receptor β- Chain in Peripheral Blood Serves as Severity Biomarker of Respiratory Failure in Newborns. | 1 |
| 34729943 | 2021 | Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer. | 4 |
| 33589587 | 2021 | Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis. | 17 |
| 33784678 | 2021 | The Truncated Splice Variant of the Granulocyte-Macrophage-Colony-Stimulating Factor Receptor β- Chain in Peripheral Blood Serves as Severity Biomarker of Respiratory Failure in Newborns. | 1 |
| 34729943 | 2021 | Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer. | 4 |
| 30124884 | 2019 | Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. | 5 |
| 30124884 | 2019 | Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. | 5 |
| 29892279 | 2018 | Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3(+)CD4(+) T Cells. | 18 |
| 29892279 | 2018 | Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3(+)CD4(+) T Cells. | 18 |
| 28131718 | 2017 | Spleen tyrosine kinase mediates the actions of EPO and GM-CSF and coordinates with TGF-β in erythropoiesis. | 5 |
| 28131718 | 2017 | Spleen tyrosine kinase mediates the actions of EPO and GM-CSF and coordinates with TGF-β in erythropoiesis. | 5 |
| 27373512 | 2016 | Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families. | 28 |
Citation
Dessen P
CSF2RB (colony stimulating factor 2 receptor subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40163/csf2rb
