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CSF2RB (colony stimulating factor 2 receptor beta common subunit)

Identity

Other namesCD131
CDw131
IL3RB
IL5RB
SMDP5
HGNC (Hugo) CSF2RB
LocusID (NCBI) 1439
Atlas_Id 40163
Location 22q12.3
Location_base_pair Starts at 37309675 and ends at 37336479 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATXN1L (16q22.2) / CSF2RB (22q12.3)CTTN (11q13.3) / CSF2RB (22q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CSF2RB   2436
Cards
Entrez_Gene (NCBI)CSF2RB  1439  colony stimulating factor 2 receptor beta common subunit
GeneCards (Weizmann)CSF2RB
Ensembl hg19 (Hinxton)ENSG00000100368 [Gene_View]  chr22:37309675-37336479 [Contig_View]  CSF2RB [Vega]
Ensembl hg38 (Hinxton)ENSG00000100368 [Gene_View]  chr22:37309675-37336479 [Contig_View]  CSF2RB [Vega]
ICGC DataPortalENSG00000100368
TCGA cBioPortalCSF2RB
AceView (NCBI)CSF2RB
Genatlas (Paris)CSF2RB
WikiGenes1439
SOURCE (Princeton)CSF2RB
Genomic and cartography
GoldenPath hg19 (UCSC)CSF2RB  -     chr22:37309675-37336479 +  22q12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CSF2RB  -     22q12.3   [Description]    (hg38-Dec_2013)
EnsemblCSF2RB - 22q12.3 [CytoView hg19]  CSF2RB - 22q12.3 [CytoView hg38]
Mapping of homologs : NCBICSF2RB [Mapview hg19]  CSF2RB [Mapview hg38]
OMIM138981   614370   
Gene and transcription
Genbank (Entrez)AK302993 BC070085 CR456428 CU012989 CU013277
RefSeq transcript (Entrez)NM_000395
RefSeq genomic (Entrez)NC_000022 NC_018933 NG_008040 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)CSF2RB
Cluster EST : UnigeneHs.592192 [ NCBI ]
CGAP (NCI)Hs.592192
Alternative Splicing : Fast-db (Paris)GSHG0019990
Alternative Splicing GalleryENSG00000100368
Gene ExpressionCSF2RB [ NCBI-GEO ]   CSF2RB [ EBI - ARRAY_EXPRESS ]   CSF2RB [ SEEK ]   CSF2RB [ MEM ]
Gene Expression Viewer (FireBrowse)CSF2RB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1439
Protein : pattern, domain, 3D structure
UniProt/SwissProtP32927 (Uniprot)
NextProtP32927  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP32927
Splice isoforms : SwissVarP32927 (Swissvar)
PhosPhoSitePlusP32927
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    HEMATOPO_REC_S_F1 (PS01355)   
Domains : Interpro (EBI)FN3_dom    Hempt_rcpt_S_F1_CS    Ig-like_fold    IL3_rcpt_beta    TypeI_recpt_CBD   
Domain families : Pfam (Sanger)fn3 (PF00041)    IL6Ra-bind (PF09240)   
Domain families : Pfam (NCBI)pfam00041    pfam09240   
Domain families : Smart (EMBL)FN3 (SM00060)  
DMDM Disease mutations1439
Blocks (Seattle)CSF2RB
PDB (SRS)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
PDB (PDBSum)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
PDB (IMB)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
PDB (RSDB)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
Structural Biology KnowledgeBase1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
SCOP (Structural Classification of Proteins)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
CATH (Classification of proteins structures)1C8P    1EGJ    1GH7    2GYS    4NKQ    5DWU   
SuperfamilyP32927
Human Protein AtlasENSG00000100368
Peptide AtlasP32927
HPRD00739
IPIIPI00465234   IPI00879222   IPI00879346   IPI01012760   
Protein Interaction databases
DIP (DOE-UCLA)P32927
IntAct (EBI)P32927
FunCoupENSG00000100368
BioGRIDCSF2RB
STRING (EMBL)CSF2RB
ZODIACCSF2RB
Ontologies - Pathways
QuickGOP32927
Ontology : AmiGOMAPK cascade  protein tyrosine kinase activity  receptor activity  interleukin-3 receptor activity  interleukin-5 receptor activity  Ras guanyl-nucleotide exchange factor activity  protein binding  intracellular  plasma membrane  integral component of plasma membrane  signal transduction  respiratory gaseous exchange  peptidyl-tyrosine phosphorylation  granulocyte macrophage colony-stimulating factor receptor complex  cellular response to interleukin-3  interleukin-5-mediated signaling pathway  interleukin-3-mediated signaling pathway  positive regulation of GTPase activity  cellular protein metabolic process  
Ontology : EGO-EBIMAPK cascade  protein tyrosine kinase activity  receptor activity  interleukin-3 receptor activity  interleukin-5 receptor activity  Ras guanyl-nucleotide exchange factor activity  protein binding  intracellular  plasma membrane  integral component of plasma membrane  signal transduction  respiratory gaseous exchange  peptidyl-tyrosine phosphorylation  granulocyte macrophage colony-stimulating factor receptor complex  cellular response to interleukin-3  interleukin-5-mediated signaling pathway  interleukin-3-mediated signaling pathway  positive regulation of GTPase activity  cellular protein metabolic process  
Pathways : BIOCARTAIL 3 signaling pathway [Genes]    Regulation of BAD phosphorylation [Genes]   
Pathways : KEGGCytokine-cytokine receptor interaction    Apoptosis    Jak-STAT signaling pathway   
NDEx Network
Atlas of Cancer Signalling NetworkCSF2RB
Wikipedia pathwaysCSF2RB
Orthology - Evolution
OrthoDB1439
GeneTree (enSembl)ENSG00000100368
Phylogenetic Trees/Animal Genes : TreeFamCSF2RB
Homologs : HomoloGeneCSF2RB
Homology/Alignments : Family Browser (UCSC)CSF2RB
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCSF2RB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSF2RB
dbVarCSF2RB
ClinVarCSF2RB
1000_GenomesCSF2RB 
Exome Variant ServerCSF2RB
ExAC (Exome Aggregation Consortium)CSF2RB (select the gene name)
SNP (GeneSNP Utah)CSF2RB
SNP : HGBaseCSF2RB
Genetic variants : HAPMAPCSF2RB
Genomic Variants (DGV)CSF2RB [DGVbeta]
Mutations
ICGC Data PortalCSF2RB 
TCGA Data PortalCSF2RB 
Broad Tumor PortalCSF2RB
OASIS PortalCSF2RB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSF2RB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CSF2RB
DgiDB (Drug Gene Interaction Database)CSF2RB
DoCM (Curated mutations)CSF2RB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSF2RB (select a term)
intoGenCSF2RB
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:37309675-37336479
CONAN: Copy Number AnalysisCSF2RB 
Mutations and Diseases : HGMDCSF2RB
OMIM138981    614370   
MedgenCSF2RB
Genetic Testing Registry CSF2RB
NextProtP32927 [Medical]
TSGene1439
GENETestsCSF2RB
Huge Navigator CSF2RB [HugePedia]  CSF2RB [HugeCancerGEM]
snp3D : Map Gene to Disease1439
BioCentury BCIQCSF2RB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1439
Chemical/Pharm GKB GenePA26939
Clinical trialCSF2RB
Miscellaneous
canSAR (ICR)CSF2RB (select the gene name)
Probes
Litterature
PubMed92 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSF2RB
GoPubMedCSF2RB
iHOPCSF2RB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 17:41:17 CEST 2016

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