Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CSF3 (colony stimulating factor 3 (granulocyte))

Identity

Other namesC17orf33
CSF3OS
GCSF
HGNC (Hugo) CSF3
LocusID (NCBI) 1440
Location 17q21.1
Location_base_pair Starts at 38171614 and ends at 38174066 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CSF3   2438
Entrez_Gene (NCBI)CSF3  1440  colony stimulating factor 3 (granulocyte)
Cards
GeneCards (Weizmann)CSF3
Ensembl (Hinxton)ENSG00000108342 [Gene_View]  chr17:38171614-38174066 [Contig_View]  CSF3 [Vega]
AceView (NCBI)CSF3
Genatlas (Paris)CSF3
SOURCE (Stanford)NM_000759 NM_001178147 NM_172219 NM_172220
Genomic and cartography
GoldenPath (UCSC)CSF3  -  17q21.1   chr17:38171614-38174066 +  17q21.1   [Description]    (hg19-Feb_2009)
EnsemblCSF3 - 17q21.1 [CytoView]
Mapping of homologs : NCBICSF3 [Mapview]
OMIM138970   
Gene and transcription
Genbank (Entrez)AB102881 AK290247 AK298116 AK313509 BC033245
RefSeq transcript (SRS)NM_000759 NM_001178147 NM_172219 NM_172220
RefSeq transcript (Entrez)NM_000759 NM_001178147 NM_172219 NM_172220
RefSeq genomic (SRS)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838435 NW_004078092
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838435 NW_004078092
Consensus coding sequences : CCDS (NCBI)CSF3
Cluster EST : UnigeneHs.2233 [ SRS ] Hs.2233 [ NCBI ]
CGAP (NCI)Hs.2233
Alternative Splicing : Fast-db (Paris)GSHG0012468
Alternative Splicing GalleryENSG00000108342
Gene ExpressionCSF3 [ NCBI-GEO ]   CSF3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09919 (SRS) P09919 (Uniprot)
NextProtP09919
With graphics : InterProP09919
Splice isoforms : SwissVarP09919(Swissvar)
Domaine pattern : Prosite (SRS)INTERLEUKIN_6 (PS00254)   
Domaine pattern : Prosite (Expaxy)INTERLEUKIN_6 (PS00254)   
Domains : Interpro (SRS)4_helix_cytokine-like_core    4_helix_cytokine_core    IL6_MGF_GCSF   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    IL6_MGF_GCSF   
Related proteins : CluSTrP09919
Domain families : Pfam (SRS)IL6 (PF00489)   
Domain families : Pfam (Sanger)IL6 (PF00489)   
Domain families : Pfam (NCBI)pfam00489   
Domain families : Smart (EMBL)IL6 (SM00126)  
DMDM1440
Blocks (Seattle)P09919
PDB (SRS)1CD9    1GNC    1PGR    1RHG    2D9Q   
PDB (PDBSum)1CD9    1GNC    1PGR    1RHG    2D9Q   
PDB (IMB)1CD9    1GNC    1PGR    1RHG    2D9Q   
PDB (RSDB)1CD9    1GNC    1PGR    1RHG    2D9Q   
Human Protein AtlasENSG00000108342
HPRD00736
IPIIPI00018306   IPI00172503   IPI00554529   IPI00794757   IPI00172504   IPI00793324   
Protein Interaction databases
DIP (DOE-UCLA)P09919
IntAct (EBI)P09919
FunCoupENSG00000108342
REACTOMECSF3
Protein Interaction Database1440
BioGRIDCSF3
InParanoidP09919
Interologous Interaction database P09919
IntegromeDBCSF3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CSF3
SNP (GeneSNP Utah)CSF3
SNP : HGBaseCSF3
Genetic variants : HAPMAPCSF3
Somatic Mutations in Cancer : COSMICCSF3 
CONAN: Copy Number AnalysisCSF3 
Mutations and Diseases : HGMDCSF3
OMIM138970   
GENETests138970   
Disease Genetic AssociationCSF3
Huge Navigator CSF3 [HugePedia]  CSF3 [HugeCancerGEM]
Genomic VariantsCSF3  CSF3 [DGVbeta]
snp3D : Map Gene to Disease1440
General knowledge
Homologs : HomoloGeneCSF3
Homology/Alignments : Family Browser (UCSC)CSF3
Phylogenetic Trees/Animal Genes : TreeFamCSF3
Chemical/Protein Interactions : CTD1440
Chemical/Pharm GKB GenePA26941
Clinical trialCSF3
Cancer Resource (Charite)ENSG00000108342
Ontology : AmiGOcytokine activity  cytokine activity  granulocyte colony-stimulating factor receptor binding  extracellular space  immune response  multicellular organismal development  growth factor activity  positive regulation of cell proliferation  positive regulation of phosphatidylinositol 3-kinase cascade  cytokine-mediated signaling pathway  enzyme binding  positive regulation of actin filament polymerization  granulocyte differentiation  positive regulation of protein binding  positive regulation of peptidyl-serine phosphorylation  positive regulation of transcription factor import into nucleus  positive regulation of transcription from RNA polymerase II promoter  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of protein kinase B signaling cascade  cellular response to cytokine stimulus  positive regulation of actin cytoskeleton reorganization  
Ontology : EGO-EBIcytokine activity  cytokine activity  granulocyte colony-stimulating factor receptor binding  extracellular space  immune response  multicellular organismal development  growth factor activity  positive regulation of cell proliferation  positive regulation of phosphatidylinositol 3-kinase cascade  cytokine-mediated signaling pathway  enzyme binding  positive regulation of actin filament polymerization  granulocyte differentiation  positive regulation of protein binding  positive regulation of peptidyl-serine phosphorylation  positive regulation of transcription factor import into nucleus  positive regulation of transcription from RNA polymerase II promoter  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of protein kinase B signaling cascade  cellular response to cytokine stimulus  positive regulation of actin cytoskeleton reorganization  
Pathways : BIOCARTARegulation of hematopoiesis by cytokines [Genes]    Erythrocyte Differentiation Pathway [Genes]    Cytokines and Inflammatory Response [Genes]    Adhesion and Diapedesis of Granulocytes [Genes]    IL 17 Signaling Pathway [Genes]   
Pathways : KEGGJak-STAT signaling pathwayCytokine-cytokine receptor interactionHematopoietic cell lineage
Other databases
Probes
Litterature
PubMed152 Pubmed reference(s) in Entrez
PubGeneCSF3
iHOPCSF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:43:14 CEST 2013
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