CSH2 (chorionic somatomammotropin hormone 2)

2014-11-01  

Identity

HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
CS-2,CSB,GHB1,PL,hCS-B
FUSION GENES

Other Information

Locus ID:

NCBI: 1443
MIM: 118820
HGNC: 2441
Ensembl: ENSG00000213218

Variants:

dbSNP: 1443
ClinVar: 1443
TCGA: ENSG00000213218
COSMIC: CSH2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213218ENST00000336844P0DML3
ENSG00000213218ENST00000336844A6NIT4
ENSG00000213218ENST00000345366P0DML3
ENSG00000213218ENST00000345366B1A4H9
ENSG00000213218ENST00000392886P0DML3
ENSG00000213218ENST00000392886A0A0M6L0F6
ENSG00000213218ENST00000560142H0YM39
ENSG00000213218ENST00000613718A0A087WUG6

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Jak-STAT signaling pathwayKEGGko04630
Neuroactive ligand-receptor interactionKEGGhsa04080
Jak-STAT signaling pathwayKEGGhsa04630
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
155315132004Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.11
223870442012Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.9
127039792002Type I collagen synthesis by human osteoblasts in response to placental lactogen and chaperonin 10, a homolog of early-pregnancy factor.2
217375192011Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.1

Citation

Dessen P

CSH2 (chorionic somatomammotropin hormone 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62122/csh2