Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CSH2 (chorionic somatomammotropin hormone 2)

Identity

Alias_symbol (synonym)hCS-B
CSB
CS-2
Other aliasGHB1
PL
HGNC (Hugo) CSH2
LocusID (NCBI) 1443
Atlas_Id 62122
Location 17q23.3  [Link to chromosome band 17q23]
Location_base_pair Starts at 63872012 and ends at 63873729 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CSH2 (17q23.3) / ORMDL1 (2q32.2)DCP1A (3p21.1) / CSH2 (17q23.3)FN1 (2q35) / CSH2 (17q23.3)
HBA2 (16p13.3) / CSH2 (17q23.3)ISYNA1 (19p13.11) / CSH2 (17q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CSH2   2441
Cards
Entrez_Gene (NCBI)CSH2  1443  chorionic somatomammotropin hormone 2
AliasesCS-2; CSB; GHB1; PL; 
hCS-B
GeneCards (Weizmann)CSH2
Ensembl hg19 (Hinxton)ENSG00000213218 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213218 [Gene_View]  chr17:63872012-63873729 [Contig_View]  CSH2 [Vega]
ICGC DataPortalENSG00000213218
TCGA cBioPortalCSH2
AceView (NCBI)CSH2
Genatlas (Paris)CSH2
WikiGenes1443
SOURCE (Princeton)CSH2
Genetics Home Reference (NIH)CSH2
Genomic and cartography
GoldenPath hg38 (UCSC)CSH2  -     chr17:63872012-63873729 -  17q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSH2  -     17q23.3   [Description]    (hg19-Feb_2009)
EnsemblCSH2 - 17q23.3 [CytoView hg19]  CSH2 - 17q23.3 [CytoView hg38]
Mapping of homologs : NCBICSH2 [Mapview hg19]  CSH2 [Mapview hg38]
OMIM118820   
Gene and transcription
Genbank (Entrez)BC022044 BC035965 BC119748 CR615915 DQ892826
RefSeq transcript (Entrez)NM_020991 NM_022644 NM_022645
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CSH2
Cluster EST : UnigeneHs.654515 [ NCBI ]
CGAP (NCI)Hs.654515
Alternative Splicing GalleryENSG00000213218
Gene ExpressionCSH2 [ NCBI-GEO ]   CSH2 [ EBI - ARRAY_EXPRESS ]   CSH2 [ SEEK ]   CSH2 [ MEM ]
Gene Expression Viewer (FireBrowse)CSH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1443
GTEX Portal (Tissue expression)CSH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0DML3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0DML3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0DML3
Splice isoforms : SwissVarP0DML3
PhosPhoSitePlusP0DML3
Domaine pattern : Prosite (Expaxy)SOMATOTROPIN_1 (PS00266)    SOMATOTROPIN_2 (PS00338)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Somatotropin    Somatotropin_CS   
Domain families : Pfam (Sanger)Hormone_1 (PF00103)   
Domain families : Pfam (NCBI)pfam00103   
Conserved Domain (NCBI)CSH2
DMDM Disease mutations1443
Blocks (Seattle)CSH2
SuperfamilyP0DML3
Human Protein AtlasENSG00000213218
Peptide AtlasP0DML3
HPRD06688
Protein Interaction databases
DIP (DOE-UCLA)P0DML3
IntAct (EBI)P0DML3
FunCoupENSG00000213218
BioGRIDCSH2
STRING (EMBL)CSH2
ZODIACCSH2
Ontologies - Pathways
QuickGOP0DML3
Ontology : AmiGOhormone activity  extracellular region  endoplasmic reticulum  vesicle  metal ion binding  
Ontology : EGO-EBIhormone activity  extracellular region  endoplasmic reticulum  vesicle  metal ion binding  
Pathways : KEGGNeuroactive ligand-receptor interaction    PI3K-Akt signaling pathway    Jak-STAT signaling pathway   
NDEx NetworkCSH2
Atlas of Cancer Signalling NetworkCSH2
Wikipedia pathwaysCSH2
Orthology - Evolution
OrthoDB1443
GeneTree (enSembl)ENSG00000213218
Phylogenetic Trees/Animal Genes : TreeFamCSH2
HOVERGENP0DML3
HOGENOMP0DML3
Homologs : HomoloGeneCSH2
Homology/Alignments : Family Browser (UCSC)CSH2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSH2
dbVarCSH2
ClinVarCSH2
1000_GenomesCSH2 
Exome Variant ServerCSH2
ExAC (Exome Aggregation Consortium)CSH2 (select the gene name)
Genetic variants : HAPMAP1443
Genomic Variants (DGV)CSH2 [DGVbeta]
DECIPHERCSH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSH2 
Mutations
ICGC Data PortalCSH2 
TCGA Data PortalCSH2 
Broad Tumor PortalCSH2
OASIS PortalCSH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCSH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CSH2
DgiDB (Drug Gene Interaction Database)CSH2
DoCM (Curated mutations)CSH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSH2 (select a term)
intoGenCSH2
Cancer3DCSH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118820   
Orphanet
MedgenCSH2
Genetic Testing Registry CSH2
NextProtP0DML3 [Medical]
TSGene1443
GENETestsCSH2
Target ValidationCSH2
Huge Navigator CSH2 [HugePedia]
snp3D : Map Gene to Disease1443
BioCentury BCIQCSH2
ClinGenCSH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1443
Chemical/Pharm GKB GenePA26944
Clinical trialCSH2
Miscellaneous
canSAR (ICR)CSH2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSH2
EVEXCSH2
GoPubMedCSH2
iHOPCSH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:44:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.