Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CSNK2A1 (casein kinase 2 alpha 1)

Identity

Alias_namescasein kinase 2
Other aliasCK2A1
CKII
CSNK2A3
OCNDS
HGNC (Hugo) CSNK2A1
LocusID (NCBI) 1457
Atlas_Id 43221
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 482694 and ends at 543838 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CNBP (3q21.3) / CSNK2A1 (20p13)CSNK2A1 (20p13) / CSNK2A1 (20p13)SH3GLB1 (1p22.3) / CSNK2A1 (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CSNK2A1   2457
Cards
Entrez_Gene (NCBI)CSNK2A1  1457  casein kinase 2 alpha 1
AliasesCK2A1; CKII; CSNK2A3; OCNDS
GeneCards (Weizmann)CSNK2A1
Ensembl hg19 (Hinxton)ENSG00000101266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101266 [Gene_View]  chr20:482694-543838 [Contig_View]  CSNK2A1 [Vega]
ICGC DataPortalENSG00000101266
TCGA cBioPortalCSNK2A1
AceView (NCBI)CSNK2A1
Genatlas (Paris)CSNK2A1
WikiGenes1457
SOURCE (Princeton)CSNK2A1
Genetics Home Reference (NIH)CSNK2A1
Genomic and cartography
GoldenPath hg38 (UCSC)CSNK2A1  -     chr20:482694-543838 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSNK2A1  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblCSNK2A1 - 20p13 [CytoView hg19]  CSNK2A1 - 20p13 [CytoView hg38]
Mapping of homologs : NCBICSNK2A1 [Mapview hg19]  CSNK2A1 [Mapview hg38]
OMIM115440   617062   
Gene and transcription
Genbank (Entrez)AB451279 AB451411 AK302583 AK312535 AU130091
RefSeq transcript (Entrez)NM_001895 NM_177559 NM_177560
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CSNK2A1
Cluster EST : UnigeneHs.644056 [ NCBI ]
CGAP (NCI)Hs.644056
Alternative Splicing GalleryENSG00000101266
Gene ExpressionCSNK2A1 [ NCBI-GEO ]   CSNK2A1 [ EBI - ARRAY_EXPRESS ]   CSNK2A1 [ SEEK ]   CSNK2A1 [ MEM ]
Gene Expression Viewer (FireBrowse)CSNK2A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1457
GTEX Portal (Tissue expression)CSNK2A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP68400   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP68400  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP68400
Splice isoforms : SwissVarP68400
PhosPhoSitePlusP68400
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)CSNK2A1
DMDM Disease mutations1457
Blocks (Seattle)CSNK2A1
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyP68400
Human Protein AtlasENSG00000101266
Peptide AtlasP68400
HPRD00277
IPIIPI00744507   IPI00741317   IPI00016613   IPI00472911   
Protein Interaction databases
DIP (DOE-UCLA)P68400
IntAct (EBI)P68400
FunCoupENSG00000101266
BioGRIDCSNK2A1
STRING (EMBL)CSNK2A1
ZODIACCSNK2A1
Ontologies - Pathways
QuickGOP68400
Ontology : AmiGOprotein serine/threonine kinase activity  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  protein kinase CK2 complex  transcription, DNA-templated  regulation of transcription, DNA-templated  protein folding  protein phosphorylation  phosphatidylcholine biosynthetic process  apoptotic process  signal transduction  positive regulation of cell proliferation  Wnt signaling pathway  kinase activity  Sin3 complex  NuRD complex  peptidyl-threonine phosphorylation  positive regulation of Wnt signaling pathway  positive regulation of cell growth  PcG protein complex  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of protein catabolic process  protein N-terminus binding  rhythmic process  Hsp90 protein binding  chaperone-mediated protein folding  mitotic spindle checkpoint  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  protein kinase CK2 complex  transcription, DNA-templated  regulation of transcription, DNA-templated  protein folding  protein phosphorylation  phosphatidylcholine biosynthetic process  apoptotic process  signal transduction  positive regulation of cell proliferation  Wnt signaling pathway  kinase activity  Sin3 complex  NuRD complex  peptidyl-threonine phosphorylation  positive regulation of Wnt signaling pathway  positive regulation of cell growth  PcG protein complex  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of protein catabolic process  protein N-terminus binding  rhythmic process  Hsp90 protein binding  chaperone-mediated protein folding  mitotic spindle checkpoint  regulation of signal transduction by p53 class mediator  
Pathways : BIOCARTA [Genes]   
Pathways : KEGGRibosome biogenesis in eukaryotes    NF-kappa B signaling pathway    Wnt signaling pathway    Adherens junction    Tight junction    Measles    Herpes simplex infection    Epstein-Barr virus infection   
NDEx NetworkCSNK2A1
Atlas of Cancer Signalling NetworkCSNK2A1
Wikipedia pathwaysCSNK2A1
Orthology - Evolution
OrthoDB1457
GeneTree (enSembl)ENSG00000101266
Phylogenetic Trees/Animal Genes : TreeFamCSNK2A1
HOVERGENP68400
HOGENOMP68400
Homologs : HomoloGeneCSNK2A1
Homology/Alignments : Family Browser (UCSC)CSNK2A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSNK2A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSNK2A1
dbVarCSNK2A1
ClinVarCSNK2A1
1000_GenomesCSNK2A1 
Exome Variant ServerCSNK2A1
ExAC (Exome Aggregation Consortium)CSNK2A1 (select the gene name)
Genetic variants : HAPMAP1457
Genomic Variants (DGV)CSNK2A1 [DGVbeta]
DECIPHERCSNK2A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSNK2A1 
Mutations
ICGC Data PortalCSNK2A1 
TCGA Data PortalCSNK2A1 
Broad Tumor PortalCSNK2A1
OASIS PortalCSNK2A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSNK2A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCSNK2A1
intOGen PortalCSNK2A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)The Globin Gene Server
BioMutasearch CSNK2A1
DgiDB (Drug Gene Interaction Database)CSNK2A1
DoCM (Curated mutations)CSNK2A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSNK2A1 (select a term)
intoGenCSNK2A1
Cancer3DCSNK2A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM115440    617062   
Orphanet
MedgenCSNK2A1
Genetic Testing Registry CSNK2A1
NextProtP68400 [Medical]
TSGene1457
GENETestsCSNK2A1
Target ValidationCSNK2A1
Huge Navigator CSNK2A1 [HugePedia]
snp3D : Map Gene to Disease1457
BioCentury BCIQCSNK2A1
ClinGenCSNK2A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1457
Chemical/Pharm GKB GenePA26957
Clinical trialCSNK2A1
Miscellaneous
canSAR (ICR)CSNK2A1 (select the gene name)
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSNK2A1
EVEXCSNK2A1
GoPubMedCSNK2A1
iHOPCSNK2A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:29:46 CEST 2017

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