Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CSNK2A2 (casein kinase 2 alpha 2)

Identity

Other namesCK2A2
CK2alpha'
CSNK2A1
HGNC (Hugo) CSNK2A2
LocusID (NCBI) 1459
Atlas_Id 40171
Location 16q21
Location_base_pair Starts at 58191812 and ends at 58231782 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MAP3K1 (5q11.2) / CSNK2A2 (16q21)RAB7A (3q21.3) / CSNK2A2 (16q21)RPL10 (Xq28) / CSNK2A2 (16q21)
USP10 (16q24.1) / CSNK2A2 (16q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CSNK2A2   2459
Cards
Entrez_Gene (NCBI)CSNK2A2  1459  casein kinase 2 alpha 2
GeneCards (Weizmann)CSNK2A2
Ensembl hg19 (Hinxton)ENSG00000070770 [Gene_View]  chr16:58191812-58231782 [Contig_View]  CSNK2A2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000070770 [Gene_View]  chr16:58191812-58231782 [Contig_View]  CSNK2A2 [Vega]
ICGC DataPortalENSG00000070770
TCGA cBioPortalCSNK2A2
AceView (NCBI)CSNK2A2
Genatlas (Paris)CSNK2A2
WikiGenes1459
SOURCE (Princeton)CSNK2A2
Genomic and cartography
GoldenPath hg19 (UCSC)CSNK2A2  -     chr16:58191812-58231782 -  16q21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CSNK2A2  -     16q21   [Description]    (hg38-Dec_2013)
EnsemblCSNK2A2 - 16q21 [CytoView hg19]  CSNK2A2 - 16q21 [CytoView hg38]
Mapping of homologs : NCBICSNK2A2 [Mapview hg19]  CSNK2A2 [Mapview hg38]
OMIM115442   
Gene and transcription
Genbank (Entrez)AI150700 AK090752 AK125922 BC008812 DQ893025
RefSeq transcript (Entrez)NM_001896
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CSNK2A2
Cluster EST : UnigeneHs.82201 [ NCBI ]
CGAP (NCI)Hs.82201
Alternative Splicing : Fast-db (Paris)GSHG0011878
Alternative Splicing GalleryENSG00000070770
Gene ExpressionCSNK2A2 [ NCBI-GEO ]   CSNK2A2 [ EBI - ARRAY_EXPRESS ]   CSNK2A2 [ SEEK ]   CSNK2A2 [ MEM ]
Gene Expression Viewer (FireBrowse)CSNK2A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1459
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19784 (Uniprot)
NextProtP19784  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19784
Splice isoforms : SwissVarP19784 (Swissvar)
PhosPhoSitePlusP19784
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations1459
Blocks (Seattle)CSNK2A2
PDB (SRS)3E3B    3OFM    3U87   
PDB (PDBSum)3E3B    3OFM    3U87   
PDB (IMB)3E3B    3OFM    3U87   
PDB (RSDB)3E3B    3OFM    3U87   
Structural Biology KnowledgeBase3E3B    3OFM    3U87   
SCOP (Structural Classification of Proteins)3E3B    3OFM    3U87   
CATH (Classification of proteins structures)3E3B    3OFM    3U87   
SuperfamilyP19784
Human Protein AtlasENSG00000070770
Peptide AtlasP19784
HPRD00279
IPIIPI00020602   
Protein Interaction databases
DIP (DOE-UCLA)P19784
IntAct (EBI)P19784
FunCoupENSG00000070770
BioGRIDCSNK2A2
STRING (EMBL)CSNK2A2
ZODIACCSNK2A2
Ontologies - Pathways
QuickGOP19784
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  protein folding  protein phosphorylation  apoptotic process  Wnt signaling pathway  PcG protein complex  protein N-terminus binding  mitotic spindle checkpoint  regulation of signal transduction by p53 class mediator  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  protein folding  protein phosphorylation  apoptotic process  Wnt signaling pathway  PcG protein complex  protein N-terminus binding  mitotic spindle checkpoint  regulation of signal transduction by p53 class mediator  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  
Pathways : KEGGRibosome biogenesis in eukaryotes    NF-kappa B signaling pathway    Wnt signaling pathway    Adherens junction    Tight junction    Measles    Herpes simplex infection    Epstein-Barr virus infection   
NDEx Network
Atlas of Cancer Signalling NetworkCSNK2A2
Wikipedia pathwaysCSNK2A2
Orthology - Evolution
OrthoDB1459
GeneTree (enSembl)ENSG00000070770
Phylogenetic Trees/Animal Genes : TreeFamCSNK2A2
Homologs : HomoloGeneCSNK2A2
Homology/Alignments : Family Browser (UCSC)CSNK2A2
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCSNK2A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSNK2A2
dbVarCSNK2A2
ClinVarCSNK2A2
1000_GenomesCSNK2A2 
Exome Variant ServerCSNK2A2
ExAC (Exome Aggregation Consortium)CSNK2A2 (select the gene name)
SNP (GeneSNP Utah)CSNK2A2
SNP : HGBaseCSNK2A2
Genetic variants : HAPMAPCSNK2A2
Genomic Variants (DGV)CSNK2A2 [DGVbeta]
Mutations
ICGC Data PortalCSNK2A2 
TCGA Data PortalCSNK2A2 
Broad Tumor PortalCSNK2A2
OASIS PortalCSNK2A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSNK2A2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CSNK2A2
DgiDB (Drug Gene Interaction Database)CSNK2A2
DoCM (Curated mutations)CSNK2A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSNK2A2 (select a term)
intoGenCSNK2A2
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:58191812-58231782
CONAN: Copy Number AnalysisCSNK2A2 
Mutations and Diseases : HGMDCSNK2A2
OMIM115442   
MedgenCSNK2A2
Genetic Testing Registry CSNK2A2
NextProtP19784 [Medical]
TSGene1459
GENETestsCSNK2A2
Huge Navigator CSNK2A2 [HugePedia]  CSNK2A2 [HugeCancerGEM]
snp3D : Map Gene to Disease1459
BioCentury BCIQCSNK2A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1459
Chemical/Pharm GKB GenePA26959
Clinical trialCSNK2A2
Miscellaneous
canSAR (ICR)CSNK2A2 (select the gene name)
Probes
Litterature
PubMed209 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSNK2A2
GoPubMedCSNK2A2
iHOPCSNK2A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Apr 16 17:41:20 CEST 2016

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