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CSNK2B (casein kinase 2 beta)

Identity

Alias (NCBI)CK2B
CK2N
CSK2B
Ckb1
Ckb2
G5A
POBINDS
HGNC (Hugo) CSNK2B
HGNC Alias symbCkb1
Ckb2
HGNC Previous namecasein kinase 2, beta polypeptide
LocusID (NCBI) 1460
Atlas_Id 40172
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 31666080 and ends at 31670067 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CSNK2B (6p21.33)::MICA (6p21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CSNK2B   2460
Cards
Entrez_Gene (NCBI)CSNK2B    casein kinase 2 beta
AliasesCK2B; CK2N; CSK2B; Ckb1; 
Ckb2; G5A; POBINDS
GeneCards (Weizmann)CSNK2B
Ensembl hg19 (Hinxton)ENSG00000204435 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204435 [Gene_View]  ENSG00000204435 [Sequence]  chr6:31666080-31670067 [Contig_View]  CSNK2B [Vega]
ICGC DataPortalENSG00000204435
TCGA cBioPortalCSNK2B
AceView (NCBI)CSNK2B
Genatlas (Paris)CSNK2B
SOURCE (Princeton)CSNK2B
Genetics Home Reference (NIH)CSNK2B
Genomic and cartography
GoldenPath hg38 (UCSC)CSNK2B  -     chr6:31666080-31670067 +  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSNK2B  -     6p21.33   [Description]    (hg19-Feb_2009)
GoldenPathCSNK2B - 6p21.33 [CytoView hg19]  CSNK2B - 6p21.33 [CytoView hg38]
ImmunoBaseENSG00000204435
Genome Data Viewer NCBICSNK2B [Mapview hg19]  
OMIM115441   618732   
Gene and transcription
Genbank (Entrez)AK300671 AK308742 AK310551 AK310954 AK311860
RefSeq transcript (Entrez)NM_001282385 NM_001320
Consensus coding sequences : CCDS (NCBI)CSNK2B
Gene ExpressionCSNK2B [ NCBI-GEO ]   CSNK2B [ EBI - ARRAY_EXPRESS ]   CSNK2B [ SEEK ]   CSNK2B [ MEM ]
Gene Expression Viewer (FireBrowse)CSNK2B [ Firebrowse - Broad ]
GenevisibleExpression of CSNK2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1460
GTEX Portal (Tissue expression)CSNK2B
Human Protein AtlasENSG00000204435-CSNK2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP67870   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP67870  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP67870
PhosPhoSitePlusP67870
Domaine pattern : Prosite (Expaxy)CK2_BETA (PS01101)   
Domains : Interpro (EBI)Casein_kin_II_reg-sub_N    Casein_kinase_II_beta-like    Casein_kinase_II_reg-sub   
Domain families : Pfam (Sanger)CK_II_beta (PF01214)   
Domain families : Pfam (NCBI)pfam01214   
Domain families : Smart (EMBL)CK_II_beta (SM01085)  
Conserved Domain (NCBI)CSNK2B
PDB (RSDB)1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
PDB Europe1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
PDB (PDBSum)1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
PDB (IMB)1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
Structural Biology KnowledgeBase1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
SCOP (Structural Classification of Proteins)1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
CATH (Classification of proteins structures)1DS5    1JWH    1QF8    3EED    4DGL    4MD7    4MD8    4MD9    4NH1    6Q38   
SuperfamilyP67870
AlphaFold pdb e-kbP67870   
Human Protein Atlas [tissue]ENSG00000204435-CSNK2B [tissue]
HPRD00278
Protein Interaction databases
DIP (DOE-UCLA)P67870
IntAct (EBI)P67870
BioGRIDCSNK2B
STRING (EMBL)CSNK2B
ZODIACCSNK2B
Ontologies - Pathways
QuickGOP67870
Ontology : AmiGOchromatin  chromatin binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  signaling receptor binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  cytoplasm  cytoplasm  cytosol  plasma membrane  cilium  protein kinase CK2 complex  protein kinase CK2 complex  protein kinase CK2 complex  protein folding  phosphatidylcholine biosynthetic process  mitotic chromosome condensation  signal transduction  transcription factor binding  negative regulation of cell population proliferation  positive regulation of pathway-restricted SMAD protein phosphorylation  Wnt signaling pathway  macroautophagy  nuclear matrix  peptidyl-threonine phosphorylation  protein kinase regulator activity  protein kinase regulator activity  protein domain specific binding  positive regulation of activin receptor signaling pathway  adiponectin-activated signaling pathway  response to testosterone  cellular protein-containing complex assembly  secretory granule lumen  identical protein binding  ribonucleoprotein complex binding  neutrophil degranulation  negative regulation of blood vessel endothelial cell migration  regulation of protein kinase activity  metal ion binding  regulation of DNA binding  endothelial tube morphogenesis  extracellular exosome  regulation of protein serine/threonine phosphatase activity  liver regeneration  regulation of signal transduction by p53 class mediator  ficolin-1-rich granule lumen  
Ontology : EGO-EBIchromatin  chromatin binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  signaling receptor binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  cytoplasm  cytoplasm  cytosol  plasma membrane  cilium  protein kinase CK2 complex  protein kinase CK2 complex  protein kinase CK2 complex  protein folding  phosphatidylcholine biosynthetic process  mitotic chromosome condensation  signal transduction  transcription factor binding  negative regulation of cell population proliferation  positive regulation of pathway-restricted SMAD protein phosphorylation  Wnt signaling pathway  macroautophagy  nuclear matrix  peptidyl-threonine phosphorylation  protein kinase regulator activity  protein kinase regulator activity  protein domain specific binding  positive regulation of activin receptor signaling pathway  adiponectin-activated signaling pathway  response to testosterone  cellular protein-containing complex assembly  secretory granule lumen  identical protein binding  ribonucleoprotein complex binding  neutrophil degranulation  negative regulation of blood vessel endothelial cell migration  regulation of protein kinase activity  metal ion binding  regulation of DNA binding  endothelial tube morphogenesis  extracellular exosome  regulation of protein serine/threonine phosphatase activity  liver regeneration  regulation of signal transduction by p53 class mediator  ficolin-1-rich granule lumen  
Pathways : KEGGRibosome biogenesis in eukaryotes    NF-kappa B signaling pathway    Wnt signaling pathway    Adherens junction    Tight junction    Measles    Herpes simplex infection    Epstein-Barr virus infection   
NDEx NetworkCSNK2B
Atlas of Cancer Signalling NetworkCSNK2B
Wikipedia pathwaysCSNK2B
Orthology - Evolution
OrthoDB1460
GeneTree (enSembl)ENSG00000204435
Phylogenetic Trees/Animal Genes : TreeFamCSNK2B
Homologs : HomoloGeneCSNK2B
Homology/Alignments : Family Browser (UCSC)CSNK2B
Gene fusions - Rearrangements
Fusion : QuiverCSNK2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSNK2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSNK2B
dbVarCSNK2B
ClinVarCSNK2B
MonarchCSNK2B
1000_GenomesCSNK2B 
Exome Variant ServerCSNK2B
GNOMAD BrowserENSG00000204435
Varsome BrowserCSNK2B
ACMGCSNK2B variants
VarityP67870
Genomic Variants (DGV)CSNK2B [DGVbeta]
DECIPHERCSNK2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSNK2B 
Mutations
ICGC Data PortalCSNK2B 
TCGA Data PortalCSNK2B 
Broad Tumor PortalCSNK2B
OASIS PortalCSNK2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSNK2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCSNK2B
Mutations and Diseases : HGMDCSNK2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCSNK2B
DgiDB (Drug Gene Interaction Database)CSNK2B
DoCM (Curated mutations)CSNK2B
CIViC (Clinical Interpretations of Variants in Cancer)CSNK2B
Cancer3DCSNK2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM115441    618732   
Orphanet
DisGeNETCSNK2B
MedgenCSNK2B
Genetic Testing Registry CSNK2B
NextProtP67870 [Medical]
GENETestsCSNK2B
Target ValidationCSNK2B
Huge Navigator CSNK2B [HugePedia]
ClinGenCSNK2B
Clinical trials, drugs, therapy
MyCancerGenomeCSNK2B
Protein Interactions : CTDCSNK2B
Pharm GKB GenePA26960
PharosP67870
Clinical trialCSNK2B
Miscellaneous
canSAR (ICR)CSNK2B
HarmonizomeCSNK2B
ARCHS4CSNK2B
DataMed IndexCSNK2B
Probes
Litterature
PubMed317 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCSNK2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jan 17 15:20:31 CET 2022

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