Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CSPG4 (chondroitin sulfate proteoglycan 4)

Identity

Alias (NCBI)CSPG4A
HMW-MAA
MCSP
MCSPG
MEL-CSPG
MSK16
NG2
HGNC (Hugo) CSPG4
HGNC Alias symbMCSPG
MEL-CSPG
MSK16
NG2
MCSP
HMW-MAA
HGNC Alias namemelanoma-associated chondroitin sulfate proteoglycan
HGNC Previous namechondroitin sulfate proteoglycan 4 (melanoma-associated)
LocusID (NCBI) 1464
Atlas_Id 40174
Location 15q24.2  [Link to chromosome band 15q24]
Location_base_pair Starts at 75674322 and ends at 75712848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CSPG4 (15q24.2) / SON (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)CSPG4   2466
Cards
Entrez_Gene (NCBI)CSPG4  1464  chondroitin sulfate proteoglycan 4
AliasesCSPG4A; HMW-MAA; MCSP; MCSPG; 
MEL-CSPG; MSK16; NG2
GeneCards (Weizmann)CSPG4
Ensembl hg19 (Hinxton)ENSG00000173546 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173546 [Gene_View]  ENSG00000173546 [Sequence]  chr15:75674322-75712848 [Contig_View]  CSPG4 [Vega]
ICGC DataPortalENSG00000173546
TCGA cBioPortalCSPG4
AceView (NCBI)CSPG4
Genatlas (Paris)CSPG4
WikiGenes1464
SOURCE (Princeton)CSPG4
Genetics Home Reference (NIH)CSPG4
Genomic and cartography
GoldenPath hg38 (UCSC)CSPG4  -     chr15:75674322-75712848 -  15q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSPG4  -     15q24.2   [Description]    (hg19-Feb_2009)
GoldenPathCSPG4 - 15q24.2 [CytoView hg19]  CSPG4 - 15q24.2 [CytoView hg38]
ImmunoBaseENSG00000173546
genome Data Viewer NCBICSPG4 [Mapview hg19]  
OMIM601172   
Gene and transcription
Genbank (Entrez)AY359468 BC033194 BC128110 BP363063 BQ679485
RefSeq transcript (Entrez)NM_001897
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CSPG4
Alternative Splicing GalleryENSG00000173546
Gene ExpressionCSPG4 [ NCBI-GEO ]   CSPG4 [ EBI - ARRAY_EXPRESS ]   CSPG4 [ SEEK ]   CSPG4 [ MEM ]
Gene Expression Viewer (FireBrowse)CSPG4 [ Firebrowse - Broad ]
GenevisibleExpression of CSPG4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1464
GTEX Portal (Tissue expression)CSPG4
Human Protein AtlasENSG00000173546-CSPG4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UVK1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UVK1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UVK1
Splice isoforms : SwissVarQ6UVK1
PhosPhoSitePlusQ6UVK1
Domaine pattern : Prosite (Expaxy)CSPG (PS51854)    LAM_G_DOMAIN (PS50025)   
Domains : Interpro (EBI)ConA-like_dom_sf    CSPG_rpt    Laminin_G   
Domain families : Pfam (Sanger)Laminin_G_1 (PF00054)    Laminin_G_2 (PF02210)   
Domain families : Pfam (NCBI)pfam00054    pfam02210   
Domain families : Smart (EMBL)LamG (SM00282)  
Conserved Domain (NCBI)CSPG4
DMDM Disease mutations1464
Blocks (Seattle)CSPG4
SuperfamilyQ6UVK1
Human Protein Atlas [tissue]ENSG00000173546-CSPG4 [tissue]
Peptide AtlasQ6UVK1
HPRD03105
IPIIPI00019157   IPI00978131   
Protein Interaction databases
DIP (DOE-UCLA)Q6UVK1
IntAct (EBI)Q6UVK1
FunCoupENSG00000173546
BioGRIDCSPG4
STRING (EMBL)CSPG4
ZODIACCSPG4
Ontologies - Pathways
QuickGOQ6UVK1
Ontology : AmiGOactivation of MAPK activity  angiogenesis  ruffle  extracellular region  nucleoplasm  Golgi lumen  plasma membrane  integral component of plasma membrane  focal adhesion  substrate-dependent cell migration  cell proliferation  glial cell migration  cell surface  cell surface  coreceptor activity  apical plasma membrane  protein kinase binding  chondroitin sulfate biosynthetic process  chondroitin sulfate catabolic process  dermatan sulfate biosynthetic process  lamellipodium membrane  intracellular signal transduction  lysosomal lumen  platelet-derived growth factor receptor signaling pathway  tissue remodeling  positive regulation of peptidyl-tyrosine phosphorylation  collagen-containing extracellular matrix  extracellular exosome  ruffle assembly  
Ontology : EGO-EBIactivation of MAPK activity  angiogenesis  ruffle  extracellular region  nucleoplasm  Golgi lumen  plasma membrane  integral component of plasma membrane  focal adhesion  substrate-dependent cell migration  cell proliferation  glial cell migration  cell surface  cell surface  coreceptor activity  apical plasma membrane  protein kinase binding  chondroitin sulfate biosynthetic process  chondroitin sulfate catabolic process  dermatan sulfate biosynthetic process  lamellipodium membrane  intracellular signal transduction  lysosomal lumen  platelet-derived growth factor receptor signaling pathway  tissue remodeling  positive regulation of peptidyl-tyrosine phosphorylation  collagen-containing extracellular matrix  extracellular exosome  ruffle assembly  
NDEx NetworkCSPG4
Atlas of Cancer Signalling NetworkCSPG4
Wikipedia pathwaysCSPG4
Orthology - Evolution
OrthoDB1464
GeneTree (enSembl)ENSG00000173546
Phylogenetic Trees/Animal Genes : TreeFamCSPG4
HOGENOMQ6UVK1
Homologs : HomoloGeneCSPG4
Homology/Alignments : Family Browser (UCSC)CSPG4
Gene fusions - Rearrangements
Fusion : QuiverCSPG4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSPG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSPG4
dbVarCSPG4
ClinVarCSPG4
MonarchCSPG4
1000_GenomesCSPG4 
Exome Variant ServerCSPG4
GNOMAD BrowserENSG00000173546
Varsome BrowserCSPG4
Genetic variants : HAPMAP1464
Genomic Variants (DGV)CSPG4 [DGVbeta]
DECIPHERCSPG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSPG4 
Mutations
ICGC Data PortalCSPG4 
TCGA Data PortalCSPG4 
Broad Tumor PortalCSPG4
OASIS PortalCSPG4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSPG4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCSPG4
Mutations and Diseases : HGMDCSPG4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CSPG4
DgiDB (Drug Gene Interaction Database)CSPG4
DoCM (Curated mutations)CSPG4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSPG4 (select a term)
intoGenCSPG4
Cancer3DCSPG4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601172   
Orphanet
DisGeNETCSPG4
MedgenCSPG4
Genetic Testing Registry CSPG4
NextProtQ6UVK1 [Medical]
TSGene1464
GENETestsCSPG4
Target ValidationCSPG4
Huge Navigator CSPG4 [HugePedia]
snp3D : Map Gene to Disease1464
BioCentury BCIQCSPG4
ClinGenCSPG4
Clinical trials, drugs, therapy
Protein Interactions : CTD1464
Pharm GKB GenePA26963
Clinical trialCSPG4
Miscellaneous
canSAR (ICR)CSPG4 (select the gene name)
HarmonizomeCSPG4
DataMed IndexCSPG4
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSPG4
EVEXCSPG4
GoPubMedCSPG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 14 14:07:29 CEST 2020

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