Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CST2 (cystatin SA)

Identity

Other alias-
HGNC (Hugo) CST2
LocusID (NCBI) 1470
Atlas_Id 62143
Location 20p11.21  [Link to chromosome band 20p11]
Location_base_pair Starts at 23823767 and ends at 23826675 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CST2   2474
Cards
Entrez_Gene (NCBI)CST2  1470  cystatin SA
Aliases
GeneCards (Weizmann)CST2
Ensembl hg19 (Hinxton)ENSG00000170369 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170369 [Gene_View]  chr20:23823767-23826675 [Contig_View]  CST2 [Vega]
ICGC DataPortalENSG00000170369
TCGA cBioPortalCST2
AceView (NCBI)CST2
Genatlas (Paris)CST2
WikiGenes1470
SOURCE (Princeton)CST2
Genetics Home Reference (NIH)CST2
Genomic and cartography
GoldenPath hg38 (UCSC)CST2  -     chr20:23823767-23826675 -  20p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CST2  -     20p11.21   [Description]    (hg19-Feb_2009)
EnsemblCST2 - 20p11.21 [CytoView hg19]  CST2 - 20p11.21 [CytoView hg38]
Mapping of homologs : NCBICST2 [Mapview hg19]  CST2 [Mapview hg38]
OMIM123856   
Gene and transcription
Genbank (Entrez)BC062679 HQ447594
RefSeq transcript (Entrez)NM_001322
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CST2
Cluster EST : UnigeneHs.669305 [ NCBI ]
CGAP (NCI)Hs.669305
Alternative Splicing GalleryENSG00000170369
Gene ExpressionCST2 [ NCBI-GEO ]   CST2 [ EBI - ARRAY_EXPRESS ]   CST2 [ SEEK ]   CST2 [ MEM ]
Gene Expression Viewer (FireBrowse)CST2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1470
GTEX Portal (Tissue expression)CST2
Human Protein AtlasENSG00000170369-CST2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09228   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09228  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09228
Splice isoforms : SwissVarP09228
PhosPhoSitePlusP09228
Domaine pattern : Prosite (Expaxy)CYSTATIN (PS00287)   
Domains : Interpro (EBI)Cystatin    Cystatin_dom    Prot_inh_cystat_CS   
Domain families : Pfam (Sanger)Cystatin (PF00031)   
Domain families : Pfam (NCBI)pfam00031   
Domain families : Smart (EMBL)CY (SM00043)  
Conserved Domain (NCBI)CST2
DMDM Disease mutations1470
Blocks (Seattle)CST2
SuperfamilyP09228
Human Protein Atlas [tissue]ENSG00000170369-CST2 [tissue]
Peptide AtlasP09228
HPRD00461
IPIIPI00013382   
Protein Interaction databases
DIP (DOE-UCLA)P09228
IntAct (EBI)P09228
FunCoupENSG00000170369
BioGRIDCST2
STRING (EMBL)CST2
ZODIACCST2
Ontologies - Pathways
QuickGOP09228
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular space  negative regulation of endopeptidase activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular space  negative regulation of endopeptidase activity  
Pathways : KEGGSalivary secretion   
NDEx NetworkCST2
Atlas of Cancer Signalling NetworkCST2
Wikipedia pathwaysCST2
Orthology - Evolution
OrthoDB1470
GeneTree (enSembl)ENSG00000170369
Phylogenetic Trees/Animal Genes : TreeFamCST2
HOVERGENP09228
HOGENOMP09228
Homologs : HomoloGeneCST2
Homology/Alignments : Family Browser (UCSC)CST2
Gene fusions - Rearrangements
Tumor Fusion PortalCST2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCST2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CST2
dbVarCST2
ClinVarCST2
1000_GenomesCST2 
Exome Variant ServerCST2
ExAC (Exome Aggregation Consortium)ENSG00000170369
GNOMAD BrowserENSG00000170369
Genetic variants : HAPMAP1470
Genomic Variants (DGV)CST2 [DGVbeta]
DECIPHERCST2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCST2 
Mutations
ICGC Data PortalCST2 
TCGA Data PortalCST2 
Broad Tumor PortalCST2
OASIS PortalCST2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCST2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCST2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CST2
DgiDB (Drug Gene Interaction Database)CST2
DoCM (Curated mutations)CST2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CST2 (select a term)
intoGenCST2
Cancer3DCST2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123856   
Orphanet
DisGeNETCST2
MedgenCST2
Genetic Testing Registry CST2
NextProtP09228 [Medical]
TSGene1470
GENETestsCST2
Target ValidationCST2
Huge Navigator CST2 [HugePedia]
snp3D : Map Gene to Disease1470
BioCentury BCIQCST2
ClinGenCST2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1470
Chemical/Pharm GKB GenePA26975
Clinical trialCST2
Miscellaneous
canSAR (ICR)CST2 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCST2
EVEXCST2
GoPubMedCST2
iHOPCST2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:41:20 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.