CST7 (cystatin F)

2003-06-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
CMAP
FUSION GENES

Other Information

Locus ID:

NCBI: 8530
MIM: 603253
HGNC: 2479
Ensembl: ENSG00000077984

Variants:

dbSNP: 8530
ClinVar: 8530
TCGA: ENSG00000077984
COSMIC: CST7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077984ENST00000480798O76096

Expression (GTEx)

0
500
1000
1500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182567002008Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis.37
166011152006Structural basis of reduction-dependent activation of human cystatin F.20
157523682005Inhibitory properties of cystatin F and its localization in U937 promonocyte cells.18
213444762011Microglial cystatin F expression is a sensitive indicator for ongoing demyelination with concurrent remyelination.18
152129602004Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting.17
223651462012Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells.16
191922502009Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources.15
124233482002Regulated expression and intracellular localization of cystatin F in human U937 cells.13
300331482018The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages.3
310591052019Cystatin F as a key family 2 cystatin subunit and prognostic biomarker for early‑stage pancreatic ductal adenocarcinoma.1

Citation

Dessen P

CST7 (cystatin F)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40179/cst7